Short-term dietary reduction of branched-chain amino acids reduces meal-induced insulin secretion and modifies microbiome composition in type 2 diabetes: a randomized controlled crossover trial

Measurement of postprandial glucose fluxes in response to acute and chronic endurance exercise in healthy humans

(2018) Dale J. Morrison et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Meal-derived glucagon responses are related to lower hepatic phosphate concentrations in obesity and type 2 diabetes

(2018) K.S. Weber et al.   DIABETES & METABOLISM

Prediction of clamp-derived insulin sensitivity from the oral glucose insulin sensitivity index

(2018) Andrea Tura et al.   DIABETOLOGIA

FGF21 gene therapy as treatment for obesity and insulin resistance

(2018) Veronica Jimenez et al.   EMBO Molecular Medicine

Interorgan Metabolic Crosstalk in Human Insulin Resistance

(2018) Sofiya Gancheva et al.   PHYSIOLOGICAL REVIEWS

Altered Dairy Protein Intake Does Not Alter Circulatory Branched Chain Amino Acids in Healthy Adults: A Randomized Controlled Trial

(2018) Utpal Prodhan et al.   Nutrients

Isocaloric Diets High in Animal or Plant Protein Reduce Liver Fat and Inflammation in Individuals With Type 2 Diabetes

(2017) Mariya Markova et al.   GASTROENTEROLOGY

The role of whey protein in postprandial glycaemic control

(2017) Emma J. Stevenson et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Repletion of branched chain amino acids reverses mTORC1 signaling but not improved metabolism during dietary protein dilution

(2017) Adriano Maida et al.   Molecular Metabolism

Cohort profile: the German Diabetes Study (GDS)

(2016) Julia Szendroedi et al.   Cardiovascular Diabetology

Differential Patterns of Impaired Cardiorespiratory Fitness and Cardiac Autonomic Dysfunction in Recently Diagnosed Type 1 and Type 2 Diabetes

(2016) Martin Röhling et al.   DIABETES CARE

Effect of breakfast omission on subjective appetite, metabolism, acylated ghrelin and GLP-17-36 during rest and exercise

(2016) David J. Clayton et al.   NUTRITION

Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health

(2016) Luigi Fontana et al.   Cell Reports

Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism

(2016) Carles Lerin et al.   Molecular Metabolism

Metabolic responses to dietary leucine restriction involve remodeling of adipose tissue and enhanced hepatic insulin signaling

(2015) Desiree Wanders et al.   BIOFACTORS

Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis

(2015) Chrysi Koliaki et al.   Cell Metabolism

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

(2015) Medha Priyadarshini et al.   MOLECULAR ENDOCRINOLOGY

Plasma Free Amino Acid Profiles Predict Four-Year Risk of Developing Diabetes, Metabolic Syndrome, Dyslipidemia and Hypertension in Japanese Population

(2015) Minoru Yamakado et al.   Scientific Reports

Adipose Tissue Dysfunction and Altered Systemic Amino Acid Metabolism Are Associated with Non-Alcoholic Fatty Liver Disease

(2015) Sulin Cheng et al.   PLoS One

Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease

(2014) April D. Lake et al.   AMINO ACIDS

Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation

(2014) Gordon I. Smith et al.   DIABETES

High Insulin Combined With Essential Amino Acids Stimulates Skeletal Muscle Mitochondrial Protein Synthesis While Decreasing Insulin Sensitivity in Healthy Humans

(2014) Matthew M. Robinson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

FGF21 is an endocrine signal of protein restriction

(2014) Thomas Laeger et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice

(2014) Fei Xiao et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Branched-chain amino acids in metabolic signalling and insulin resistance

(2014) Christopher J. Lynch et al.   Nature Reviews Endocrinology

Validation and Comparison of Two Methods to Assess Human Energy Expenditure during Free-Living Activities

(2014) Panagiota Anastasopoulou et al.   PLoS One

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

(2014) Julia Szendroedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms Underlying the Onset of Oral Lipid-Induced Skeletal Muscle Insulin Resistance in Humans

(2013) B. Nowotny et al.   DIABETES

Assessing the Human Gut Microbiota in Metabolic Diseases

(2013) F. Karlsson et al.   DIABETES

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Leucine and Protein Metabolism in Obese Zucker Rats

(2013) Pengxiang She et al.   PLoS One

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance

(2012) Christopher B. Newgard   Cell Metabolism

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

(2011) Julia Szendroedi et al.   Nature Reviews Endocrinology

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Adipose Tissue Branched Chain Amino Acid (BCAA) Metabolism Modulates Circulating BCAA Levels

(2010) Mark A. Herman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leucine metabolism in regulation of insulin secretion from pancreatic beta cells

(2010) Jichun Yang et al.   NUTRITION REVIEWS

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism