Artificial Natural Killer Cells for Specific Tumor Inhibition and Renegade Macrophage Re‐Education

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

(2019) Mingen Liu et al.   NATURE IMMUNOLOGY

Glucose Oxidase‐Instructed Multimodal Synergistic Cancer Therapy

(2019) Lian‐Hua Fu et al.   ADVANCED MATERIALS

Nanoengineered Immune Niches for Reprogramming the Immunosuppressive Tumor Microenvironment and Enhancing Cancer Immunotherapy

(2019) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Aptamer‐Engineered Natural Killer Cells for Cell‐Specific Adaptive Immunotherapy

(2019) Shuanghui Yang et al.   Small

Nanoparticles from Cuttlefish Ink Inhibit Tumor Growth by Synergizing Immunotherapy and Photothermal Therapy

(2019) Rong-Hui Deng et al.   ACS Nano

Aggressive Man-Made Red Blood Cells for Hypoxia-Resistant Photodynamic Therapy

(2018) Wen-Long Liu et al.   ADVANCED MATERIALS

Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment

(2018) Lian-Hua Fu et al.   CHEMICAL SOCIETY REVIEWS

Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity

(2018) Lucas Ferrari de Andrade et al.   SCIENCE

A Multifunctional Biomimetic Nanoplatform for Relieving Hypoxia to Enhance Chemotherapy and Inhibit the PD-1/PD-L1 Axis

(2018) Mei-Zhen Zou et al.   Small

Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression

(2018) Wei Xiang et al.   Nature Communications

A designer self-assembled supramolecule amplifies macrophage immune responses against aggressive cancer

(2018) Ashish Kulkarni et al.   Nature Biomedical Engineering

Local Blockade of Interleukin 10 and C-X-C Motif Chemokine Ligand 12 with Nano-Delivery Promotes Antitumor Response in Murine Cancers

(2018) Limei Shen et al.   ACS Nano

Self-Supplied Tumor Oxygenation through Separated Liposomal Delivery of H2O2 and Catalase for Enhanced Radio-Immunotherapy of Cancer

(2018) Xuejiao Song et al.   NANO LETTERS

Cell-Membrane Immunotherapy Based on Natural Killer Cell Membrane Coated Nanoparticles for the Effective Inhibition of Primary and Abscopal Tumor Growth

(2018) Guanjun Deng et al.   ACS Nano

Defect-Induced Pt-Co-Se Coordinated Sites with Highly Asymmetrical Electronic Distribution for Boosting Oxygen-Involving Electrocatalysis

(2018) Linzhou Zhuang et al.   ADVANCED MATERIALS

Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells

(2018) Pascale André et al.   CELL

NKG2A, a New Kid on the Immune Checkpoint Block

(2018) John B. Haanen et al.   CELL

Reprogramming Tumor-Associated Macrophages by Nanoparticle-Based Reactive Oxygen Species Photogeneration

(2018) Changrong Shi et al.   NANO LETTERS

A biomimetic nanoreactor for synergistic chemiexcited photodynamic therapy and starvation therapy against tumor metastasis

(2018) Zhengze Yu et al.   Nature Communications

Hydrogen Peroxide: A Potential Wound Therapeutic Target

(2017) Guanya Zhu et al.   MEDICAL PRINCIPLES AND PRACTICE

Irgm1 promotes M1 but not M2 macrophage polarization in atherosclerosis pathogenesis and development

(2016) Shaohong Fang et al.   ATHEROSCLEROSIS

Galectin-12 enhances inflammation by promoting M1 polarization of macrophages and reduces insulin sensitivity in adipocytes

(2016) Lei Wan et al.   GLYCOBIOLOGY

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

Macrophage defense mechanisms against intracellular bacteria

(2015) Günter Weiss et al.   IMMUNOLOGICAL REVIEWS

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

CD47 blockade as another immune checkpoint therapy for cancer

(2015) Robert H Vonderheide   NATURE MEDICINE

CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

(2015) Xiaojuan Liu et al.   NATURE MEDICINE

HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells

(2015) Huimin Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies

(2014) G. K. Philips et al.   INTERNATIONAL IMMUNOLOGY

Checkpoint blocking antibodies in cancer immunotherapy

(2013) Chrisann Kyi et al.   FEBS LETTERS

Hydrogen Peroxide as a Damage Signal in Tissue Injury and Inflammation: Murderer, Mediator, or Messenger?

(2013) Albert van der Vliet et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma

(2013) J Chu et al.   LEUKEMIA

Innate and adaptive immune responses in asthma

(2012) Stephen T Holgate   NATURE MEDICINE

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2012) S. B. Willingham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen Peroxide as a Signaling Molecule

(2011) Elizabeth Veal et al.   ANTIOXIDANTS & REDOX SIGNALING

NK Cell Recognition and Killing of Melanoma Cells Is Controlled by Multiple Activating Receptor-Ligand Interactions

(2011) Sara Morgado et al.   Journal of Innate Immunity

The Suppressive Tumor Microenvironment: A Challenge in Cancer Immunotherapy

(2011) Elizabeth A. Vasievich et al.   MOLECULAR PHARMACEUTICS

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

(2011) D R Gough et al.   Cell Death & Disease

Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane

(2010) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Innate IFN-γ Production by Subsets of Natural Killer Cells, Natural Killer T Cells and γδ T Cells in Response to Dying Bacterial-Infected Macrophages

(2009) K. Kubota   SCANDINAVIAN JOURNAL OF IMMUNOLOGY