HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
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Title
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112, Issue 45, Pages E6215-E6223
Publisher
Proceedings of the National Academy of Sciences
Online
2015-10-29
DOI
10.1073/pnas.1520032112
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Note: Only part of the references are listed.- The hypoxic tumor microenvironment: A driving force for breast cancer progression
- (2016) Gregg L. Semenza BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- (2015) Haiquan Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) Stephen M. Hatfield et al. Science Translational Medicine
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- (2015) Lisha Xiang et al. Oncotarget
- Co-expression of MET and CD47 is a novel prognosticator for survival of luminal-type breast cancer patients
- (2015) Irène Baccelli et al. Oncotarget
- Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
- (2015) Lisha Xiang et al. Oncotarget
- Blockade of CD47-mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma
- (2014) Terence Kin-Wah Lee et al. HEPATOLOGY
- Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
- (2014) T. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
- (2014) P. Chaturvedi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells
- (2014) Debangshu Samanta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Collagen Prolyl Hydroxylases Are Essential for Breast Cancer Metastasis
- (2013) D. M. Gilkes et al. CANCER RESEARCH
- Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer
- (2013) Lisha Xiang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis
- (2013) Daniele M. Gilkes et al. MOLECULAR CANCER RESEARCH
- Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
- (2013) Irène Baccelli et al. NATURE BIOTECHNOLOGY
- Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells
- (2013) D. M. Gilkes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Making Macrophages Eat Cancer
- (2013) M. H. Kershaw et al. SCIENCE
- Abstract 4640: Quantification of gamma-H2AX expression in whole blood culture as a risk predictor for renal cell carcinoma
- (2012) Yilei Gong et al. CANCER RESEARCH
- A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
- (2012) S. K. Chia et al. CLINICAL CANCER RESEARCH
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
- (2012) Balaji Krishnamachary et al. PLoS One
- Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
- (2012) L. Schito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
- (2012) S. J. Conley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
- (2012) S. B. Willingham et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
- (2011) H Zhang et al. ONCOGENE
- GOBO: Gene Expression-Based Outcome for Breast Cancer Online
- (2011) Markus Ringnér et al. PLoS One
- Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
- (2011) C. C.-L. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene expression and hypoxia in breast cancer
- (2011) Elena Favaro et al. Genome Medicine
- Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
- (2010) M. P. Chao et al. Science Translational Medicine
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- (2009) Ravindra Majeti et al. CELL
- Histological and molecular types of breast cancer: is there a unifying taxonomy?
- (2009) Britta Weigelt et al. Nature Reviews Clinical Oncology
- Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
- (2009) Lauren K. Dunn et al. PLoS One
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- (2009) K. S. Chan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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