Surface Engineered Polymersomes for Enhanced Modulation of Dendritic Cells During Cardiovascular Immunotherapy

Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association

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Polymersomes scalably fabricated via flash nanoprecipitation are non-toxic in non-human primates and associate with leukocytes in the spleen and kidney following intravenous administration

(2018) Sean D. Allen et al.   Nano Research

Sustained micellar delivery via inducible transitions in nanostructure morphology

(2018) Nicholas B. Karabin et al.   Nature Communications

Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents

(2018) Huimin Zou et al.   Frontiers in Immunology

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

(2017) David J. Dowling et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Facile assembly and loading of theranostic polymersomes via multi-impingement flash nanoprecipitation

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Vitamin D and Cardiovascular Disease

(2017) Ibhar Al Mheid et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inflammatory Markers for Arterial Stiffness in Cardiovascular Diseases

(2017) Ioana Mozos et al.   Frontiers in Immunology

Flash nanoprecipitation permits versatile assembly and loading of polymeric bicontinuous cubic nanospheres

(2017) Sharan Bobbala et al.   Nanoscale

Tailoring Nanostructure Morphology for Enhanced Targeting of Dendritic Cells in Atherosclerosis

(2016) Sijia Yi et al.   ACS Nano

Loss of Macrophage Low-Density Lipoprotein Receptor–Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-α InhibitionHighlights

(2016) Lin Zhu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Statin-Associated Side Effects

(2016) Paul D. Thompson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vitamin D and cardiovascular disease prevention

(2016) Stefan Pilz et al.   Nature Reviews Cardiology

Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation

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Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management

(2015) Erik S. Stroes et al.   EUROPEAN HEART JOURNAL

CD8+CD205+ Splenic Dendritic Cells Are Specialized to Induce Foxp3+ Regulatory T Cells

(2014) S. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

Vitamin D Receptor Inhibits Nuclear Factor κB Activation by Interacting with IκB Kinase β Protein

(2013) Yunzi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intensification of Statin Therapy Results in a Rapid Reduction in Atherosclerotic Inflammation

(2013) Ahmed Tawakol et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis

(2013) Stefan Freigang et al.   NATURE IMMUNOLOGY

Microparticle surface modifications targeting dendritic cells for non-activating applications

(2012) Jamal S. Lewis et al.   BIOMATERIALS

Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes

(2012) Evan A. Scott et al.   BIOMATERIALS

Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor

(2012) Carsten Carlberg et al.   STEROIDS

Cardiovascular Protection by ApoE and ApoE-HDL Linked to Suppression of ECM Gene Expression and Arterial Stiffening

(2012) Devashish Kothapalli et al.   Cell Reports

Immunotherapy With Tolerogenic Apolipoprotein B-100–Loaded Dendritic Cells Attenuates Atherosclerosis in Hypercholesterolemic Mice

(2011) Andreas Hermansson et al.   CIRCULATION

Vitamin D3: a helpful immuno-modulator

(2011) Michelino Di Rosa et al.   IMMUNOLOGY

Progress and challenges in translating the biology of atherosclerosis

(2011) Peter Libby et al.   NATURE

Anti-inflammatory therapeutics for the treatment of atherosclerosis

(2011) Israel F. Charo et al.   NATURE REVIEWS DRUG DISCOVERY

Relation of Vitamin D Deficiency to Cardiovascular Risk Factors, Disease Status, and Incident Events in a General Healthcare Population

(2010) Jeffrey L. Anderson et al.   AMERICAN JOURNAL OF CARDIOLOGY

Oral Administration of an Active Form of Vitamin D 3 (Calcitriol) Decreases Atherosclerosis in Mice by Inducing Regulatory T Cells and Immature Dendritic Cells With Tolerogenic Functions

(2010) Masafumi Takeda et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Critical Role for TNF in the Induction of Human Antigen-Specific Regulatory T Cells by Tolerogenic Dendritic Cells

(2010) F. S. Kleijwegt et al.   JOURNAL OF IMMUNOLOGY

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Vitamin D and the Cardiovascular System

(2009) J. N. Artaza et al.   Clinical Journal of the American Society of Nephrology

Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists

(2009) Luciano Adorini et al.   HUMAN IMMUNOLOGY

Inflammation in Atherosclerosis

(2009) Peter Libby et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls

(2009) Dries Vercauteren et al.   MOLECULAR THERAPY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

High plasma concentrations of autoantibodies against native peptide 210 of apoB-100 are related to less coronary atherosclerosis and lower risk of myocardial infarction

(2008) P. Sjogren et al.   EUROPEAN HEART JOURNAL

Treatment with apo B peptide vaccines inhibits atherosclerosis in human apo B-100 transgenic mice without inducing an increase in peptide-specific antibodies

(2008) G. N. Fredrikson et al.   JOURNAL OF INTERNAL MEDICINE

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

(2008) Véronique Baud et al.   NATURE REVIEWS DRUG DISCOVERY