Polyphenol Microbial Metabolites Exhibit Gut and Blood–Brain Barrier Permeability and Protect Murine Microglia against LPS-Induced Inflammation

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

Beneficial Effects of Flavonoids Against Parkinson's Disease

(2018) Un Ju Jung et al.   JOURNAL OF MEDICINAL FOOD

Mediterranean diet adherence is related to reduced probability of prodromal Parkinson's disease

(2018) Maria I. Maraki et al.   MOVEMENT DISORDERS

Phenolic Compounds Characteristic of the Mediterranean Diet in Mitigating Microglia-Mediated Neuroinflammation

(2018) Ruth Hornedo-Ortega et al.   Frontiers in Cellular Neuroscience

Relationship between Mediterranean Dietary Polyphenol Intake and Obesity

(2018) Sara Castro-Barquero et al.   Nutrients

Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro

(2017) Lalita Subedi et al.   Nutrients

Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

(2017) Prachi B. Shekhawat et al.   Acta Pharmaceutica Sinica B

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Polyphenols journey through blood-brain barrier towards neuronal protection

(2017) I. Figueira et al.   Scientific Reports

In vitro evaluation of antioxidant and cytotoxic activities of lignin fractions extracted from Acacia nilotica

(2016) Anand Barapatre et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A new PAMPA model using an in-house brain lipid extract for screening the blood–brain barrier permeability of drug candidates

(2016) Joana Bicker et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effects of a Standardized Phenolic-Enriched Maple Syrup Extract on β-Amyloid Aggregation, Neuroinflammation in Microglial and Neuronal Cells, and β-Amyloid Induced Neurotoxicity in Caenorhabditis elegans

(2016) Hang Ma et al.   NEUROCHEMICAL RESEARCH

Role of Natural Stilbenes in the Prevention of Cancer

(2016) J. Antoni Sirerol et al.   Oxidative Medicine and Cellular Longevity

Pomegranate’s Neuroprotective Effects against Alzheimer’s Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites

(2015) Tao Yuan et al.   ACS Chemical Neuroscience

The Mediterranean Diet, its Components, and Cardiovascular Disease

(2015) R. Jay Widmer et al.   AMERICAN JOURNAL OF MEDICINE

Phenolic sulfates as new and highly abundant metabolites in human plasma after ingestion of a mixed berry fruit purée

(2015) Rui C. Pimpão et al.   BRITISH JOURNAL OF NUTRITION

Tuning the predictive capacity of the PAMPA-BBB model

(2015) Judit Müller et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The role of the nitric oxide pathway in brain injury and its treatment — From bench to bedside

(2015) P.S. Garry et al.   EXPERIMENTAL NEUROLOGY

The hydrolyzable gallotannin, penta-O-galloyl-β-d-glucopyranoside, inhibits the formation of advanced glycation endproducts by protecting protein structure

(2015) Hang Ma et al.   Molecular BioSystems

Poor permeability and absorption affect the activity of four alkaloids from Coptis

(2015) HAN-MING CUI et al.   Molecular Medicine Reports

Implications of glial nitric oxide in neurodegenerative diseases

(2015) Jose Enrique Yuste et al.   Frontiers in Cellular Neuroscience

Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties

(2015) Laura Marín et al.   Biomed Research International

A Method to Predict Blood-Brain Barrier Permeability of Drug-Like Compounds Using Molecular Dynamics Simulations

(2014) Timothy S. Carpenter et al.   BIOPHYSICAL JOURNAL

Permeability and Conjugative Metabolism of Flaxseed Lignans by Caco-2 Human Intestinal Cells

(2014) Jatinder Kaur Mukker et al.   JOURNAL OF NATURAL PRODUCTS

Mediterranean diet and health

(2013) Francesco Sofi et al.   BIOFACTORS

Overview of Metabolism and Bioavailability Enhancement of Polyphenols

(2013) Urszula Lewandowska et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Applicability of a Blood–Brain Barrier Specific Artificial Membrane Permeability Assay at the Early Stage of Natural Product-Based CNS Drug Discovery

(2013) Árpád Könczöl et al.   JOURNAL OF NATURAL PRODUCTS

The key involvement of estrogen receptor β and G-protein-coupled receptor 30 in the neuroprotective action of daidzein

(2013) M. Kajta et al.   NEUROSCIENCE

Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondria-dependent apoptosis pathways and reactive oxygen induced-NF-κB activation in a cerebral ischemia mouse model

(2012) Yisong Qian et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroinflammation and neurodegeneration in overnutrition-induced diseases

(2012) Dongsheng Cai   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dietary genistein and equol (4′, 7 isoflavandiol) reduce oxidative stress and protect rats against focal cerebral ischemia

(2010) Yulin Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Bioavailability of the Polyphenols: Status and Controversies

(2010) Massimo D’Archivio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Profiles of Phytoestrogens in Human Urine from Several Asian Countries

(2010) Tatsuya Kunisue et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Equol: History, Chemistry, and Formation

(2010) Kenneth D. R. Setchell et al.   JOURNAL OF NUTRITION

The Standard American Diet and Its Relationship to the Health Status of Americans

(2010) David Grotto et al.   NUTRITION IN CLINICAL PRACTICE

Dietary lignans: physiology and potential for cardiovascular disease risk reduction

(2010) Julia Peterson et al.   NUTRITION REVIEWS

Direct medical cost of overweight and obesity in the USA: a quantitative systematic review

(2010) A. G. Tsai et al.   Obesity Reviews

Plant Polyphenols as Dietary Antioxidants in Human Health and Disease

(2010) Kanti Bhooshan Pandey et al.   Oxidative Medicine and Cellular Longevity

The Medical Risks of Obesity

(2009) Xavier Pi-Sunyer   POSTGRADUATE MEDICINE