Monte Carlo Simulations for the Analysis of Non-linear Parameter Confidence Intervals in Optimal Experimental Design

Microbioreactor Systems for Accelerated Bioprocess Development

(2018) Johannes Hemmerich et al.   Biotechnology Journal

Substrate Spectra of Nucleoside Phosphorylases and their Potential in the Production of Pharmaceutically Active Compounds

(2018) Heba Yehia et al.   CURRENT PHARMACEUTICAL DESIGN

Microbioreactor Systems for Accelerated Bioprocess Development

(2018) Johannes Hemmerich et al.   Biotechnology Journal

The Impact of Global Sensitivities and Design Measures in Model-Based Optimal Experimental Design

(2018) René Schenkendorf et al.   Processes

Chemo-enzymatic synthesis of α-d-pentofuranose-1-phosphates using thermostable pyrimidine nucleoside phosphorylases

(2018) Sarah Kamel et al.   Molecular Catalysis

Sequential Model-Based A-Optimal Design of Experiments When the Fisher Information Matrix Is Noninvertible

(2018) Ali Shahmohammadi et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Online optimal experimental re-design in robotic parallel fed-batch cultivation facilities

(2016) M.N. Cruz Bournazou et al.   BIOTECHNOLOGY AND BIOENGINEERING

Online bioprocess data generation, analysis, and optimization for parallel fed-batch fermentations in milliliter scale

(2016) David Benjamin Nickel et al.   ENGINEERING IN LIFE SCIENCES

Design of experiments-based high-throughput strategy for development and optimization of efficient cell disruption protocols

(2016) Florian Glauche et al.   ENGINEERING IN LIFE SCIENCES

Nonlinear ill-posed problem analysis in model-based parameter estimation and experimental design

(2015) Diana C. López C. et al.   COMPUTERS & CHEMICAL ENGINEERING

SECOND-ORDER SENSITIVITY ANALYSIS OF PARAMETER ESTIMATION PROBLEMS

(2015) Ekaterina Kostina et al.   International Journal for Uncertainty Quantification

Model-based identifiable parameter determination applied to a simultaneous saccharification and fermentation process model for bio-ethanol production

(2013) Diana C. López C. et al.   BIOTECHNOLOGY PROGRESS

Consistent development of bioprocesses from microliter cultures to the industrial scale

(2013) Peter Neubauer et al.   ENGINEERING IN LIFE SCIENCES

Likelihood based observability analysis and confidence intervals for predictions of dynamic models

(2012) Clemens Kreutz et al.   BMC Systems Biology

Advances and selected recent developments in state and parameter estimation

(2012) Costas Kravaris et al.   COMPUTERS & CHEMICAL ENGINEERING

Comparative investigations on thermostable pyrimidine nucleoside phosphorylases from Geobacillus thermoglucosidasius and Thermus thermophilus

(2012) Kathleen Szeker et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Process systems engineering: From Solvay to modern bio- and nanotechnology.

(2011) George Stephanopoulos et al.   CHEMICAL ENGINEERING SCIENCE

Identification of a rice drying model with an improved sequential optimal design of experiments

(2011) Daniel Goujot et al.   JOURNAL OF PROCESS CONTROL

An optimal experimental design approach to model discrimination in dynamic biochemical systems

(2010) Dominik Skanda et al.   BIOINFORMATICS

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

(2009) A. Raue et al.   BIOINFORMATICS

Optimal experimental design with the sigma point method

(2009) R. Schenkendorf et al.   IET Systems Biology

Uncertainty analysis in WWTP model applications: A critical discussion using an example from design

(2009) Gürkan Sin et al.   WATER RESEARCH

Model-based design of experiments for parameter precision: State of the art

(2007) Gaia Franceschini et al.   CHEMICAL ENGINEERING SCIENCE