- Home
- Publications
- Publication Search
- Publication Details
Title
Hippo Signaling in Cancer: Lessons From Drosophila Models
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-05-24
DOI
10.3389/fcell.2019.00085
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Recruitment of Jub by α-catenin promotes Yki activity and Drosophila wing growth
- (2019) Herve Alégot et al. JOURNAL OF CELL SCIENCE
- Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation
- (2019) Mutsuko Minata et al. Cell Reports
- Wingless modulates activator protein-1-mediated tumor invasion
- (2019) Shiping Zhang et al. ONCOGENE
- K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways
- (2019) Matthias Scheffler et al. Journal of Thoracic Oncology
- Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module
- (2018) Agnidipta Ghosh et al. BIOCHEMISTRY
- The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation
- (2018) Simon Weissmann et al. CANCER RESEARCH
- Oncogenic Signaling Pathways in The Cancer Genome Atlas
- (2018) Francisco Sanchez-Vega et al. CELL
- Dynamic Fluctuations in Subcellular Localization of the Hippo Pathway Effector Yorkie In Vivo
- (2018) Samuel A. Manning et al. CURRENT BIOLOGY
- Validating upstream regulators of Yorkie activity in Hippo signaling through scalloped -based genetic epistasis
- (2018) Jianzhong Yu et al. DEVELOPMENT
- Mechanical strain regulates the Hippo pathway in Drosophila
- (2018) Georgina C. Fletcher et al. DEVELOPMENT
- Oncogenic cooperation between Yorkie and the conserved microRNAmiR-8in the wing disc ofDrosophila
- (2018) Moritz Sander et al. DEVELOPMENT
- Yorkie Functions at the Cell Cortex to Promote Myosin Activation in a Non-transcriptional Manner
- (2018) Jiajie Xu et al. DEVELOPMENTAL CELL
- ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP
- (2018) Xu Shen et al. FEBS LETTERS
- The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell
- (2018) Steven W. Plouffe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K
- (2018) Yong suk Cho et al. Nature Communications
- The Hippo Signaling Network and its Biological Functions
- (2018) Jyoti R. Misra et al. Annual Review of Genetics
- The Hippo Pathway: Biology and Pathophysiology
- (2018) Shenghong Ma et al. Annual Review of Biochemistry
- Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis
- (2018) Takahiro Kodama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-285–Yki/Mask double-negative feedback loop mediates blood–brain barrier integrity inDrosophila
- (2017) Dong Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Genetic Screen Reveals an Unexpected Role for Yorkie Signaling in JAK/STAT-Dependent Hematopoietic Malignancies in Drosophila melanogaster
- (2017) Abigail M. Anderson et al. G3-Genes Genomes Genetics
- Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration
- (2017) Emilie Simon et al. Biology Open
- Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila
- (2016) Saskia J.E. Suijkerbuijk et al. CURRENT BIOLOGY
- An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model
- (2016) Mardelle Atkins et al. CURRENT BIOLOGY
- Drosophila Schip1 Links Expanded and Tao-1 to Regulate Hippo Signaling
- (2016) Hyung-Lok Chung et al. DEVELOPMENTAL CELL
- Mechanisms of Hippo pathway regulation
- (2016) Zhipeng Meng et al. GENES & DEVELOPMENT
- AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol
- (2016) Radhika Jagannathan et al. MOLECULAR AND CELLULAR BIOLOGY
- Domain-specific functions of Stardust inDrosophilaembryonic development
- (2016) Leonie Koch et al. Royal Society Open Science
- Loss of Cell Adhesion Increases Tumorigenic Potential of Polarity Deficient Scribble Mutant Cells
- (2016) Indrayani Waghmare et al. PLoS One
- Non-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesis
- (2015) Masato Enomoto et al. CANCER SCIENCE
- Zyxin Antagonizes the FERM Protein Expanded to Couple F-Actin and Yorkie-Dependent Organ Growth
- (2015) Pedro Gaspar et al. CURRENT BIOLOGY
- Ajuba proteins
- (2015) Gregory V. Schimizzi et al. CURRENT BIOLOGY
- JNK signaling is converted from anti- to pro-tumor pathway by Ras-mediated switch of Warts activity
- (2015) Masato Enomoto et al. DEVELOPMENTAL BIOLOGY
- Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade
- (2015) Yonggang Zheng et al. DEVELOPMENTAL CELL
- Interplay amongDrosophilatranscription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy
- (2015) Eva Külshammer et al. Disease Models & Mechanisms
- Localization and Function of Pals1-associated Tight Junction Protein inDrosophilaIs Regulated by Two Distinct Apical Complexes
- (2015) Arnab Sen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biochemical Large-Scale Interaction Analysis of Murine Olfactory Receptors and Associated Signaling Proteins with Post-Synaptic Density 95, Drosophila Discs Large, Zona-Occludens 1 (PDZ) Domains
- (2015) Fabian Jansen et al. MOLECULAR & CELLULAR PROTEOMICS
- Niche appropriation by Drosophila intestinal stem cell tumours
- (2015) Parthive H. Patel et al. NATURE CELL BIOLOGY
- MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
- (2015) Zhipeng Meng et al. Nature Communications
- Scaling the Drosophila Wing: TOR-Dependent Target Gene Access by the Hippo Pathway Transducer Yorkie
- (2015) Joseph Parker et al. PLOS BIOLOGY
- Salt-inducible kinases mediate nutrient-sensing to link dietary sugar and tumorigenesis in Drosophila
- (2015) Susumu Hirabayashi et al. eLife
- Kicking it up a Notch for the best in show: Scalloped leads Yorkie into the haematopoietic arena
- (2015) Gabriel B Ferguson et al. FLY
- Cross-talk between Wnt/β-catenin and Hippo signaling pathways: a brief review
- (2014) Minseong Kim et al. BMB Reports
- The Conserved Misshapen-Warts-Yorkie Pathway Acts in Enteroblasts to Regulate Intestinal Stem Cells in Drosophila
- (2014) Qi Li et al. DEVELOPMENTAL CELL
- Dissecting tumour heterogeneity in flies: genetic basis of interclonal oncogenic cooperation
- (2014) Shizue Ohsawa et al. JOURNAL OF BIOCHEMISTRY
- Intercellular Cooperation and Competition in Brain Cancers: Lessons FromDrosophilaand Human Studies
- (2014) Indrayani Waghmare et al. Stem Cells Translational Medicine
- Transformed Drosophila Cells Evade Diet-Mediated Insulin Resistance through Wingless Signaling
- (2013) Susumu Hirabayashi et al. CELL
- A novel partner of Scalloped regulates Hippo signaling via antagonizing Scalloped-Yorkie activity
- (2013) Tong Guo et al. CELL RESEARCH
- Wingless/Wnt signaling in Drosophila: The pattern and the pathway
- (2013) Amy Bejsovec MOLECULAR REPRODUCTION AND DEVELOPMENT
- Ajuba Family Proteins Link JNK to Hippo Signaling
- (2013) G. Sun et al. Science Signaling
- The Hippo pathway acts via p53 and microRNAs to control proliferation and proapoptotic gene expression during tissue growth
- (2013) W. Zhang et al. Biology Open
- Regulators of mammalian Hippo pathway in cancer
- (2012) Angela M. Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Hippo signalling controls Dronc activity to regulate organ size in Drosophila
- (2012) S Verghese et al. CELL DEATH AND DIFFERENTIATION
- Separating planar cell polarity and Hippo pathway activities of the protocadherins Fat and Dachsous
- (2012) H. Matakatsu et al. DEVELOPMENT
- Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP
- (2012) Katrin Straßburger et al. DEVELOPMENTAL BIOLOGY
- Understanding resistance to targeted cancer drugs through loss of function genetic screens
- (2012) Katrien Berns et al. DRUG RESISTANCE UPDATES
- Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila
- (2012) Masato Enomoto et al. EMBO REPORTS
- Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
- (2012) B. Zhao et al. GENES & DEVELOPMENT
- Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila
- (2012) Shizue Ohsawa et al. NATURE
- YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29
- (2012) Karen Tumaneng et al. NATURE CELL BIOLOGY
- Notch Signaling Activates Yorkie Non-Cell Autonomously in Drosophila
- (2012) Hillary K. Graves et al. PLoS One
- Scribble Acts in the Drosophila Fat-Hippo Pathway to Regulate Warts Activity
- (2012) Shilpi Verghese et al. PLoS One
- Protein kinases of the Hippo pathway: Regulation and substrates
- (2012) Joseph Avruch et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway
- (2012) Wanjin Hong et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Hippo pathway in intestinal homeostasis and tumorigenesis
- (2012) Lanfen Chen et al. Protein & Cell
- Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling
- (2011) Karen Doggett et al. BMC DEVELOPMENTAL BIOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Drosophila endocytic neoplastic tumor suppressor genes regulate Sav/Wts/Hpo signaling and the c-Jun N-terminal kinase pathway
- (2011) Brian S. Robinson et al. CELL CYCLE
- A dp53/JNK-dependant feedback amplification loop is essential for the apoptotic response to stress in Drosophila
- (2011) E Shlevkov et al. CELL DEATH AND DIFFERENTIATION
- Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador–Warts–Hippo pathway
- (2011) X Zhang et al. CELL DEATH AND DIFFERENTIATION
- MOB control: Reviewing a conserved family of kinase regulators
- (2011) Alexander Hergovich CELLULAR SIGNALLING
- Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila
- (2011) G. Kolahgar et al. DEVELOPMENT
- A Screen for Conditional Growth Suppressor Genes Identifies the Drosophila Homolog of HD-PTP as a Regulator of the Oncoprotein Yorkie
- (2011) M. Melissa Gilbert et al. DEVELOPMENTAL CELL
- Cooperative Regulation of Growth by Yorkie and Mad through bantam
- (2011) Hyangyee Oh et al. DEVELOPMENTAL CELL
- The Sterile 20-like Kinase Tao-1 Controls Tissue Growth by Regulating the Salvador-Warts-Hippo Pathway
- (2011) Carole L.C. Poon et al. DEVELOPMENTAL CELL
- Tao-1 Phosphorylates Hippo/MST Kinases to Regulate the Hippo-Salvador-Warts Tumor Suppressor Pathway
- (2011) Julian C. Boggiano et al. DEVELOPMENTAL CELL
- The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
- (2011) K. P. L. Bhat et al. GENES & DEVELOPMENT
- Salvador Protein Is a Tumor Suppressor Effector of RASSF1A with Hippo Pathway-independent Functions
- (2011) Howard Donninger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
- (2011) Bin Zhao et al. NATURE CELL BIOLOGY
- Tumor suppression by cell competition through regulation of the Hippo pathway
- (2011) C.-L. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- WW domain interactions regulate the Hippo tumor suppressor pathway
- (2011) Z Salah et al. Cell Death & Disease
- Zyxin Links Fat Signaling to the Hippo Pathway
- (2011) Cordelia Rauskolb et al. PLOS BIOLOGY
- Hippo Pathway Effector Yap Is an Ovarian Cancer Oncogene
- (2010) C. A. Hall et al. CANCER RESEARCH
- Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell Proliferation
- (2010) Binnaz Kucuk Staley et al. CURRENT BIOLOGY
- Ajuba LIM Proteins Are Negative Regulators of the Hippo Signaling Pathway
- (2010) Meghna Das Thakur et al. CURRENT BIOLOGY
- Lgl, aPKC, and Crumbs Regulate the Salvador/Warts/Hippo Pathway through Two Distinct Mechanisms
- (2010) Nicola A. Grzeschik et al. CURRENT BIOLOGY
- Crumbs Regulates Salvador/Warts/Hippo Signaling in Drosophila via the FERM-Domain Protein Expanded
- (2010) Brian S. Robinson et al. CURRENT BIOLOGY
- Influence of Fat-Hippo and Notch signaling on the proliferation and differentiation of Drosophila optic neuroepithelia
- (2010) B. V. V. G. Reddy et al. DEVELOPMENT
- The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration
- (2010) P. Karpowicz et al. DEVELOPMENT
- Hippo signaling: growth control and beyond
- (2010) G. Halder et al. DEVELOPMENT
- Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors
- (2010) Gongping Sun et al. DEVELOPMENTAL BIOLOGY
- The WW Domain Protein Kibra Acts Upstream of Hippo in Drosophila
- (2010) Roland Baumgartner et al. DEVELOPMENTAL CELL
- Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded
- (2010) Jianzhong Yu et al. DEVELOPMENTAL CELL
- The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway
- (2010) Xaralabos Varelas et al. DEVELOPMENTAL CELL
- Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network
- (2010) Alice Genevet et al. DEVELOPMENTAL CELL
- An autoinhibitory effect of the homothorax domain of Meis2
- (2010) Cathy Hyman-Walsh et al. FEBS Journal
- Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway
- (2010) Linda M Parsons et al. FLY
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- Interaction between Ras V12 and scribbled clones induces tumour growth and invasion
- (2010) Ming Wu et al. NATURE
- WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ
- (2010) S W Chan et al. ONCOGENE
- The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
- (2010) C. Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila
- (2010) C.-L. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modularity in the Hippo signaling pathway
- (2010) Marius Sudol et al. TRENDS IN BIOCHEMICAL SCIENCES
- A Feed-Forward Circuit Linking Wingless, Fat-Dachsous Signaling, and the Warts-Hippo Pathway to Drosophila Wing Growth
- (2010) Myriam Zecca et al. PLOS BIOLOGY
- Mechanisms of Growth and Homeostasis in the Drosophila Wing
- (2009) Ricardo M. Neto-Silva et al. Annual Review of Cell and Developmental Biology
- YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human diseaseThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.
- (2009) Kainan Wang et al. Biochemistry and Cell Biology
- The RASSF proteins in cancer; from epigenetic silencing to functional characterization
- (2009) Antje M. Richter et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs
- (2009) Gregory R Leong et al. BMC BIOLOGY
- Transcriptional Output of the Salvador/Warts/Hippo Pathway Is Controlled in Distinct Fashions in Drosophila melanogaster and Mammalian Cell Lines
- (2009) X. Zhang et al. CANCER RESEARCH
- Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways
- (2009) Claudio Alarcón et al. CELL
- Phosphorylation of the Tumor Suppressor Fat Is Regulated by Its Ligand Dachsous and the Kinase Discs Overgrown
- (2009) Richelle Sopko et al. CURRENT BIOLOGY
- Drosophila lowfat, a novel modulator of Fat signaling
- (2009) Y. Mao et al. DEVELOPMENT
- Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling
- (2009) Hyangyee Oh et al. DEVELOPMENTAL BIOLOGY
- Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms
- (2009) Fangfang Ren et al. DEVELOPMENTAL BIOLOGY
- The FERM-Domain Protein Expanded Regulates Hippo Pathway Activity via Direct Interactions with the Transcriptional Activator Yorkie
- (2009) Caroline Badouel et al. DEVELOPMENTAL CELL
- Regulation of organ size: Insights from theDrosophilaHippo signaling pathway
- (2009) Madhuri Kango-Singh et al. DEVELOPMENTAL DYNAMICS
- Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc
- (2009) H. W. Peng et al. GENES & DEVELOPMENT
- The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth
- (2009) F. Hamaratoglu et al. JOURNAL OF CELL SCIENCE
- In vivo analysis of Yorkie phosphorylation sites
- (2009) H Oh et al. ONCOGENE
- Processing and phosphorylation of the Fat receptor
- (2009) Y. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development
- (2009) K. Skouloudaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Apical junctions and growth control in Drosophila
- (2008) Caroline Badouel et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Negative Regulation of YAP by LATS1 Underscores Evolutionary Conservation of the Drosophila Hippo Pathway
- (2008) J. Zhang et al. CANCER RESEARCH
- Warts Is Required for PI3K-Regulated Growth Arrest, Autophagy, and Autophagic Cell Death in Drosophila
- (2008) Sudeshna Dutta et al. CURRENT BIOLOGY
- SCALLOPED Interacts with YORKIE, the Nuclear Effector of the Hippo Tumor-Suppressor Pathway in Drosophila
- (2008) Youlian Goulev et al. CURRENT BIOLOGY
- MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation
- (2008) Maria Praskova et al. CURRENT BIOLOGY
- The Hippo–YAP pathway: new connections between regulation of organ size and cancer
- (2008) Bin Zhao et al. CURRENT OPINION IN CELL BIOLOGY
- In vivo regulation of Yorkie phosphorylation and localization
- (2008) H. Oh et al. DEVELOPMENT
- The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway
- (2008) Shian Wu et al. DEVELOPMENTAL CELL
- The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control
- (2008) Lei Zhang et al. DEVELOPMENTAL CELL
- An innate immune response of blood cells to tumors and tissue damage in Drosophila
- (2008) J. C. Pastor-Pareja et al. Disease Models & Mechanisms
- TEAD mediates YAP-dependent gene induction and growth control
- (2008) B. Zhao et al. GENES & DEVELOPMENT
- A Regulatory Circuit Controlling Itch-mediated p73 Degradation by Runx
- (2008) Dan Levy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mst2 and Lats Kinases Regulate Apoptotic Function of Yes Kinase-associated Protein (YAP)
- (2008) Tsutomu Oka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
- (2008) Xaralabos Varelas et al. NATURE CELL BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started