Tumor suppression by cell competition through regulation of the Hippo pathway

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

(2011) Karen Doggett et al.   BMC DEVELOPMENTAL BIOLOGY

Elimination of Oncogenic Neighbors by JNK-Mediated Engulfment in Drosophila

(2011) Shizue Ohsawa et al.   DEVELOPMENTAL CELL

The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy

(2010) Francesca Froldi et al.   BMC BIOLOGY

The dark side of fly TNF

(2010) Marcos Vidal   CELL CYCLE

Lgl, aPKC, and Crumbs Regulate the Salvador/Warts/Hippo Pathway through Two Distinct Mechanisms

(2010) Nicola A. Grzeschik et al.   CURRENT BIOLOGY

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster

(2010) Felix A. Grusche et al.   DEVELOPMENTAL BIOLOGY

Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors

(2010) Gongping Sun et al.   DEVELOPMENTAL BIOLOGY

Oncogenic Ras Diverts a Host TNF Tumor Suppressor Activity into Tumor Promoter

(2010) Julia B. Cordero et al.   DEVELOPMENTAL CELL

Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of Yap

(2010) Ricardo M. Neto-Silva et al.   DEVELOPMENTAL CELL

A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway

(2010) J. Menendez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis

(2010) V Tomlinson et al.   Cell Death & Disease

Mechanisms of Growth and Homeostasis in the Drosophila Wing

(2009) Ricardo M. Neto-Silva et al.   Annual Review of Cell and Developmental Biology

scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

(2009) Gregory R Leong et al.   BMC BIOLOGY

Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila

(2009) Tatsushi Igaki et al.   DEVELOPMENTAL CELL

Competitive Interactions Between Cells: Death, Growth, and Geography

(2009) L. A. Johnston   SCIENCE

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control

(2008) Lei Zhang et al.   DEVELOPMENTAL CELL

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

(2008) P O Humbert et al.   ONCOGENE