Death Receptor Interactions With the Mitochondrial Cell Death Pathway During Immune Cell-, Drug- and Toxin-Induced Liver Damage

Bax retrotranslocation potentiates Bcl-xL’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance

(2018) Annika Hantusch et al.   Cell Death & Disease

An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity

(2018) Chun-Bing Chen et al.   Journal of Immunology Research

TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation

(2018) Laura Faletti et al.   Cell Death & Disease

Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis

(2017) Prafull Kumar Singh et al.   GENES & DEVELOPMENT

Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis

(2015) Lily Dara et al.   HEPATOLOGY

Differential retrotranslocation of mitochondrial Bax and Bak

(2014) F. Todt et al.   EMBO JOURNAL

Regulation of TRAIL-Receptor Expression by the Ubiquitin-Proteasome System

(2014) Dhifaf Sarhan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TRIF and IRF-3 Binding to the TNF Promoter Results in Macrophage TNF Dysregulation and Steatosis Induced by Chronic Ethanol

(2014) X.-J. Zhao et al.   JOURNAL OF IMMUNOLOGY

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice

(2013) Anup Ramachandran et al.   HEPATOLOGY

The Role of Kupffer Cells in Carbon Tetrachloride Intoxication in Mice

(2012) Kaori Kiso et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

(2012) Charalambos Gustav Antoniades et al.   HEPATOLOGY

TRAIL Signaling and Synergy Mechanisms Used in TRAIL-Based Combination Therapies

(2012) C. T. Hellwig et al.   MOLECULAR CANCER THERAPEUTICS

TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner

(2012) A Badmann et al.   Cell Death & Disease

Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage

(2011) A Badmann et al.   Cell Death & Disease

Distinct but complementary roles of Fas ligand and Bim in homeostatic T cell apoptosis

(2010) Daniela Kassahn et al.   CELL CYCLE

Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner

(2010) Kathrin Schmich et al.   HEPATOLOGY

Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid

(2010) S Schneider-Jakob et al.   Cell Death & Disease

Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim

(2009) Thomas Kaufmann et al.   IMMUNITY

Pathogenic role of natural killer T and natural killer cells in acetaminophen-induced liver injury in mice is dependent on the presence of dimethyl sulfoxide

(2008) Mary Jane Masson et al.   HEPATOLOGY