Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses
Authors
Keywords
Alzheimer’s disease, Differently expressed genes, Systematic biological analyses, Key candidate genes, lncRNAs
Journal
HEREDITAS
Volume 156, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-16
DOI
10.1186/s41065-019-0101-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Relationship Between Alzheimer’s Disease and the Immune System: A Meta-Analysis of Differentially Expressed Genes
- (2019) Nan Wang et al. Frontiers in Neuroscience
- Global Positioning System: Understanding Long Noncoding RNAs through Subcellular Localization
- (2019) Joana Carlevaro-Fita et al. MOLECULAR CELL
- ATP-sensitive potassium-channel inhibitor glibenclamide attenuates HPA axis hyperactivity, depression- and anxiety-related symptoms in a rat model of Alzheimer's disease
- (2018) Mohammad Hossein Esmaeili et al. BRAIN RESEARCH BULLETIN
- Functional Classification and Experimental Dissection of Long Noncoding RNAs
- (2018) Florian Kopp et al. CELL
- Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain
- (2018) Melissa Barber et al. CEREBRAL CORTEX
- Evaluation of Animal Models by Comparison with Human Late-Onset Alzheimer’s Disease
- (2018) Bu-Yeo Kim et al. MOLECULAR NEUROBIOLOGY
- Faster progression from MCI to probable AD for carriers of a single-nucleotide polymorphism associated with type 2 diabetes
- (2018) Hugo Girard et al. NEUROBIOLOGY OF AGING
- Subregional volumes of the hippocampus in relation to cognitive function and risk of dementia
- (2018) Tavia E. Evans et al. NEUROIMAGE
- Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection
- (2018) William A. Eimer et al. NEURON
- Citalopram restores short-term memory deficit and non-cognitive behaviors in APP/PS1 mice while halting the advance of Alzheimer's disease-like pathology
- (2018) Qin Zhang et al. NEUROPHARMACOLOGY
- Understanding Alzheimer Disease at the Interface between Genetics and Transcriptomics
- (2018) Jan Verheijen et al. TRENDS IN GENETICS
- Alzheimer’s disease master regulators analysis: search for potential molecular targets and drug repositioning candidates
- (2018) D. M. Vargas et al. Alzheimers Research & Therapy
- Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer’s Disease
- (2018) Vinay Lanke et al. Frontiers in Aging Neuroscience
- SALL4 - KHDRBS3 network enhances stemness by modulating CD44 splicing in basal-like breast cancer
- (2018) Yoshiaki Matsumoto et al. Cancer Medicine
- Calcium Channel Blockers and Alzheimer's Disease: Potential Relevance in Treatment Strategies of Metabolic Syndrome
- (2018) William V. Goodison et al. JOURNAL OF ALZHEIMERS DISEASE
- Blood Genome-Wide Transcriptional Profiles Reflect Broad Molecular Impairments and Strong Blood-Brain Links in Alzheimer's Disease
- (2018) Bartholomew J. Naughton et al. JOURNAL OF ALZHEIMERS DISEASE
- Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies
- (2018) Mulin Xu et al. Aging-US
- Condition-specific gene co-expression network mining identifies key pathways and regulators in the brain tissue of Alzheimer’s disease patients
- (2018) Shunian Xiang et al. BMC Medical Genomics
- Network-based approach to identify molecular signatures and therapeutic agents in Alzheimer’s disease
- (2018) Md. Rezanur Rahman et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
- The Gene Ontology Resource: 20 years and still GOing strong
- (2018) NUCLEIC ACIDS RESEARCH
- Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins
- (2017) Meng Zhang et al. GENES & DEVELOPMENT
- CD44 Splice Variants as Potential Players in Alzheimer’s Disease Pathology
- (2017) Elhanan Pinner et al. JOURNAL OF ALZHEIMERS DISEASE
- Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells
- (2017) Yuanzheng Peng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetics of Alzheimer’s disease: From pathogenesis to clinical usage
- (2017) Wen Shao et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Not Just Noise: Genomics and Genetics Bring Long Noncoding RNAs into Focus
- (2017) L. Stirling Churchman MOLECULAR CELL
- The expression and activity of K V 3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice
- (2017) Francesca Boscia et al. NEUROBIOLOGY OF AGING
- Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease
- (2017) Hongjun Fu et al. NEURON
- WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research
- (2017) Denise N Slenter et al. NUCLEIC ACIDS RESEARCH
- Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony
- (2017) Stefania Forner et al. TRENDS IN NEUROSCIENCES
- Rebalancing the Addicted Brain: Oxytocin Interference with the Neural Substrates of Addiction
- (2017) Michael T. Bowen et al. TRENDS IN NEUROSCIENCES
- Oxytocin and Anxiety Disorders: Translational and Therapeutic Aspects
- (2017) Wadih Jean Naja et al. Current Psychiatry Reports
- The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer’s Disease
- (2017) Xiaocong Pang et al. Biomed Research International
- YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
- (2017) Ian A Roundtree et al. eLife
- Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection
- (2017) Cristy Phillips NEURAL PLASTICITY
- Mapping Cofilin-Actin Rods in Stressed Hippocampal Slices and the Role of cdc42 in Amyloid-β-Induced Rods
- (2017) Richard C. Davis et al. JOURNAL OF ALZHEIMERS DISEASE
- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease
- (2016) Lidia Bakota et al. DRUGS
- Stroke, Vascular Dementia, and Alzheimer’s Disease: Molecular Links
- (2016) Murali Vijayan et al. JOURNAL OF ALZHEIMERS DISEASE
- Integrated Analysis of Alzheimer’s Disease and Schizophrenia Dataset Revealed Different Expression Pattern in Learning and Memory
- (2016) Wen-Xing Li et al. JOURNAL OF ALZHEIMERS DISEASE
- Pharmacological and Nonpharmacological Treatment for Apathy in Alzheimer Disease
- (2016) Christos Theleritis et al. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
- Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis
- (2016) N Yoshimi et al. MOLECULAR PSYCHIATRY
- Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss
- (2016) Tara E. Tracy et al. NEURON
- The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
- (2016) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- KEGG: new perspectives on genomes, pathways, diseases and drugs
- (2016) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer’s disease
- (2016) Abdel G. Elkahloun et al. Alzheimers Research & Therapy
- Increased Persistent Sodium Current Causes Neuronal Hyperexcitability in the Entorhinal Cortex of Fmr1 Knockout Mice
- (2016) Pan-Yue Deng et al. Cell Reports
- Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer’s disease
- (2016) S-S Jiao et al. Translational Psychiatry
- Metabolomics and Its Application to Acute Lung Diseases
- (2016) Kathleen A. Stringer et al. Frontiers in Immunology
- Vulnerability of calbindin, calretinin and parvalbumin in a transgenic/knock-in APPswe/PS1dE9 mouse model of Alzheimer disease together with disruption of hippocampal neurogenesis
- (2015) Ester Verdaguer et al. EXPERIMENTAL GERONTOLOGY
- Genetic diagnosis and prognosis of Alzheimer’s disease: challenges and opportunities
- (2015) Christiane Reitz EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- KEGG as a reference resource for gene and protein annotation
- (2015) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- A functional polymorphism in the prodynorphin gene affects cognitive flexibility and brain activation during reversal learning
- (2015) Mikhail Votinov et al. Frontiers in Behavioral Neuroscience
- Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease
- (2015) Paola Briata et al. Wiley Interdisciplinary Reviews-RNA
- Activity-Dependent p25 Generation Regulates Synaptic Plasticity and Aβ-Induced Cognitive Impairment
- (2014) Jinsoo Seo et al. CELL
- Neuroprotection requires the functions of the RNA-binding protein HuR
- (2014) A Skliris et al. CELL DEATH AND DIFFERENTIATION
- TheRBMXgene as a candidate for the Shashi X-linked intellectual disability syndrome
- (2014) V. Shashi et al. CLINICAL GENETICS
- Alzheimer’s Disease and Type 2 Diabetes: Multiple Mechanisms Contribute to Interactions
- (2014) Anusha Jayaraman et al. Current Diabetes Reports
- VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain
- (2014) M. Tillo et al. DEVELOPMENT
- Neuronal BC RNAs cooperate with eIF4B to mediate activity-dependent translational control
- (2014) Taesun Eom et al. JOURNAL OF CELL BIOLOGY
- Loss of Calbindin immunoreactivity in the dentate gyrus distinguishes Alzheimer's disease from other neurodegenerative dementias
- (2014) Harald Stefanits et al. NEUROSCIENCE LETTERS
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R
- (2014) M. L. Kraushar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ContigScape: a Cytoscape plugin facilitating microbial genome gap closing
- (2013) Biao Tang et al. BMC GENOMICS
- Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study
- (2013) Masaaki Hokama et al. CEREBRAL CORTEX
- The Changing Landscape of Voltage-Gated Calcium Channels in Neurovascular Disorders and in Neurodegenerative Diseases
- (2013) Mauro Cataldi Current Neuropharmacology
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Glia Maturation Factor Expression in Entorhinal Cortex of Alzheimer’s Disease Brain
- (2013) Ramasamy Thangavel et al. NEUROCHEMICAL RESEARCH
- Dynorphins regulate the strength of social memory
- (2013) A. Bilkei-Gorzo et al. NEUROPHARMACOLOGY
- Novel ncRNAs transcribed by Pol III and elucidation of their functional relevance by biophysical approaches
- (2013) Paola Gavazzo et al. Frontiers in Cellular Neuroscience
- The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain
- (2013) Ingrid Ehrmann et al. PLoS Genetics
- Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation
- (2013) Christoph Jüschke et al. GENOME BIOLOGY
- Alzheimer’s Disease And Type 2 Diabetes: Exploring The Association To Obesity And Tyrosine Hydroxylase
- (2012) Medha Priyadarshini et al. CNS & Neurological Disorders-Drug Targets
- An intronic ncRNA-dependent regulation of SORL1 expression affecting A formation is upregulated in post-mortem Alzheimer's disease brain samples
- (2012) E. Ciarlo et al. Disease Models & Mechanisms
- Locus-specific mutation databases for neurodegenerative brain diseases
- (2012) Marc Cruts et al. HUMAN MUTATION
- Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
- (2012) Nicole C. Berchtold et al. NEUROBIOLOGY OF AGING
- Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative
- (2012) Shashwath A. Meda et al. NEUROBIOLOGY OF AGING
- Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling
- (2012) Neil M. Fournier et al. NEUROPHARMACOLOGY
- RNA-interacting proteins act as site-specific repressors of ADAR2-mediated RNA editing and fluctuate upon neuronal stimulation
- (2012) Aamira Tariq et al. NUCLEIC ACIDS RESEARCH
- The effect of tachykinin neuropeptides on amyloid β aggregation
- (2011) Efrat Flashner et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The dynorphin/κ-opioid receptor system and its role in psychiatric disorders
- (2011) H. A. Tejeda et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Hippocampal synaptic plasticity in Alzheimer’s disease: what have we learned so far from transgenic models?
- (2011) Cristina Marchetti et al. REVIEWS IN THE NEUROSCIENCES
- Regulatory RNAs in brain function and disorders
- (2010) Anna Iacoangeli et al. BRAIN RESEARCH
- Rac and Rho GTPases in cancer cell motility control
- (2010) Matteo Parri et al. Cell Communication and Signaling
- Role of SFRS13A in low-density lipoprotein receptor splicing
- (2010) I-Fang Ling et al. HUMAN MUTATION
- MicroRNAs-10a and -10b Contribute to Retinoic Acid-induced Differentiation of Neuroblastoma Cells and Target the Alternative Splicing Regulatory Factor SFRS1 (SF2/ASF)
- (2010) Salvador Meseguer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE
- (2010) Rita J. Guerreiro et al. NEUROBIOLOGY OF AGING
- Increased CD44 Gene Expression in Lymphocytes Derived from Alzheimer Disease Patients
- (2010) D. Uberti et al. Neurodegenerative Diseases
- Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons
- (2008) R. N. Kanadia et al. DEVELOPMENT
- Translational Control by a Small RNA: Dendritic BC1 RNA Targets the Eukaryotic Initiation Factor 4A Helicase Mechanism
- (2008) D. Lin et al. MOLECULAR AND CELLULAR BIOLOGY
- Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase
- (2008) Mohammad Ali Faghihi et al. NATURE MEDICINE
- Gene expression changes in the course of normal brain aging are sexually dimorphic
- (2008) N. C. Berchtold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started