Integrated identification of key genes and pathways in Alzheimer’s disease via comprehensive bioinformatical analyses

Relationship Between Alzheimer’s Disease and the Immune System: A Meta-Analysis of Differentially Expressed Genes

(2019) Nan Wang et al.   Frontiers in Neuroscience

Global Positioning System: Understanding Long Noncoding RNAs through Subcellular Localization

(2019) Joana Carlevaro-Fita et al.   MOLECULAR CELL

ATP-sensitive potassium-channel inhibitor glibenclamide attenuates HPA axis hyperactivity, depression- and anxiety-related symptoms in a rat model of Alzheimer's disease

(2018) Mohammad Hossein Esmaeili et al.   BRAIN RESEARCH BULLETIN

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain

(2018) Melissa Barber et al.   CEREBRAL CORTEX

Evaluation of Animal Models by Comparison with Human Late-Onset Alzheimer’s Disease

(2018) Bu-Yeo Kim et al.   MOLECULAR NEUROBIOLOGY

Faster progression from MCI to probable AD for carriers of a single-nucleotide polymorphism associated with type 2 diabetes

(2018) Hugo Girard et al.   NEUROBIOLOGY OF AGING

Subregional volumes of the hippocampus in relation to cognitive function and risk of dementia

(2018) Tavia E. Evans et al.   NEUROIMAGE

Alzheimer’s Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

(2018) William A. Eimer et al.   NEURON

Citalopram restores short-term memory deficit and non-cognitive behaviors in APP/PS1 mice while halting the advance of Alzheimer's disease-like pathology

(2018) Qin Zhang et al.   NEUROPHARMACOLOGY

Understanding Alzheimer Disease at the Interface between Genetics and Transcriptomics

(2018) Jan Verheijen et al.   TRENDS IN GENETICS

Alzheimer’s disease master regulators analysis: search for potential molecular targets and drug repositioning candidates

(2018) D. M. Vargas et al.   Alzheimers Research & Therapy

Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer’s Disease

(2018) Vinay Lanke et al.   Frontiers in Aging Neuroscience

SALL4 - KHDRBS3 network enhances stemness by modulating CD44 splicing in basal-like breast cancer

(2018) Yoshiaki Matsumoto et al.   Cancer Medicine

Calcium Channel Blockers and Alzheimer's Disease: Potential Relevance in Treatment Strategies of Metabolic Syndrome

(2018) William V. Goodison et al.   JOURNAL OF ALZHEIMERS DISEASE

Blood Genome-Wide Transcriptional Profiles Reflect Broad Molecular Impairments and Strong Blood-Brain Links in Alzheimer's Disease

(2018) Bartholomew J. Naughton et al.   JOURNAL OF ALZHEIMERS DISEASE

Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies

(2018) Mulin Xu et al.   Aging-US

Condition-specific gene co-expression network mining identifies key pathways and regulators in the brain tissue of Alzheimer’s disease patients

(2018) Shunian Xiang et al.   BMC Medical Genomics

Network-based approach to identify molecular signatures and therapeutic agents in Alzheimer’s disease

(2018) Md. Rezanur Rahman et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins

(2017) Meng Zhang et al.   GENES & DEVELOPMENT

CD44 Splice Variants as Potential Players in Alzheimer’s Disease Pathology

(2017) Elhanan Pinner et al.   JOURNAL OF ALZHEIMERS DISEASE

Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells

(2017) Yuanzheng Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetics of Alzheimer’s disease: From pathogenesis to clinical usage

(2017) Wen Shao et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Not Just Noise: Genomics and Genetics Bring Long Noncoding RNAs into Focus

(2017) L. Stirling Churchman   MOLECULAR CELL

The expression and activity of K V 3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice

(2017) Francesca Boscia et al.   NEUROBIOLOGY OF AGING

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease

(2017) Hongjun Fu et al.   NEURON

WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research

(2017) Denise N Slenter et al.   NUCLEIC ACIDS RESEARCH

Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony

(2017) Stefania Forner et al.   TRENDS IN NEUROSCIENCES

Rebalancing the Addicted Brain: Oxytocin Interference with the Neural Substrates of Addiction

(2017) Michael T. Bowen et al.   TRENDS IN NEUROSCIENCES

Oxytocin and Anxiety Disorders: Translational and Therapeutic Aspects

(2017) Wadih Jean Naja et al.   Current Psychiatry Reports

The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer’s Disease

(2017) Xiaocong Pang et al.   Biomed Research International

YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs

(2017) Ian A Roundtree et al.   eLife

Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection

(2017) Cristy Phillips   NEURAL PLASTICITY

Mapping Cofilin-Actin Rods in Stressed Hippocampal Slices and the Role of cdc42 in Amyloid-β-Induced Rods

(2017) Richard C. Davis et al.   JOURNAL OF ALZHEIMERS DISEASE

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

(2016) Lidia Bakota et al.   DRUGS

Stroke, Vascular Dementia, and Alzheimer’s Disease: Molecular Links

(2016) Murali Vijayan et al.   JOURNAL OF ALZHEIMERS DISEASE

Integrated Analysis of Alzheimer’s Disease and Schizophrenia Dataset Revealed Different Expression Pattern in Learning and Memory

(2016) Wen-Xing Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Pharmacological and Nonpharmacological Treatment for Apathy in Alzheimer Disease

(2016) Christos Theleritis et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis

(2016) N Yoshimi et al.   MOLECULAR PSYCHIATRY

Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss

(2016) Tara E. Tracy et al.   NEURON

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer’s disease

(2016) Abdel G. Elkahloun et al.   Alzheimers Research & Therapy

Increased Persistent Sodium Current Causes Neuronal Hyperexcitability in the Entorhinal Cortex of Fmr1 Knockout Mice

(2016) Pan-Yue Deng et al.   Cell Reports

Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer’s disease

(2016) S-S Jiao et al.   Translational Psychiatry

Metabolomics and Its Application to Acute Lung Diseases

(2016) Kathleen A. Stringer et al.   Frontiers in Immunology

Vulnerability of calbindin, calretinin and parvalbumin in a transgenic/knock-in APPswe/PS1dE9 mouse model of Alzheimer disease together with disruption of hippocampal neurogenesis

(2015) Ester Verdaguer et al.   EXPERIMENTAL GERONTOLOGY

Genetic diagnosis and prognosis of Alzheimer’s disease: challenges and opportunities

(2015) Christiane Reitz   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

A functional polymorphism in the prodynorphin gene affects cognitive flexibility and brain activation during reversal learning

(2015) Mikhail Votinov et al.   Frontiers in Behavioral Neuroscience

Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease

(2015) Paola Briata et al.   Wiley Interdisciplinary Reviews-RNA

Activity-Dependent p25 Generation Regulates Synaptic Plasticity and Aβ-Induced Cognitive Impairment

(2014) Jinsoo Seo et al.   CELL

Neuroprotection requires the functions of the RNA-binding protein HuR

(2014) A Skliris et al.   CELL DEATH AND DIFFERENTIATION

TheRBMXgene as a candidate for the Shashi X-linked intellectual disability syndrome

(2014) V. Shashi et al.   CLINICAL GENETICS

Alzheimer’s Disease and Type 2 Diabetes: Multiple Mechanisms Contribute to Interactions

(2014) Anusha Jayaraman et al.   Current Diabetes Reports

VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain

(2014) M. Tillo et al.   DEVELOPMENT

Neuronal BC RNAs cooperate with eIF4B to mediate activity-dependent translational control

(2014) Taesun Eom et al.   JOURNAL OF CELL BIOLOGY

Loss of Calbindin immunoreactivity in the dentate gyrus distinguishes Alzheimer's disease from other neurodegenerative dementias

(2014) Harald Stefanits et al.   NEUROSCIENCE LETTERS

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R

(2014) M. L. Kraushar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ContigScape: a Cytoscape plugin facilitating microbial genome gap closing

(2013) Biao Tang et al.   BMC GENOMICS

Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study

(2013) Masaaki Hokama et al.   CEREBRAL CORTEX

The Changing Landscape of Voltage-Gated Calcium Channels in Neurovascular Disorders and in Neurodegenerative Diseases

(2013) Mauro Cataldi   Current Neuropharmacology

Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

(2013) Tao Ma et al.   NATURE NEUROSCIENCE

Glia Maturation Factor Expression in Entorhinal Cortex of Alzheimer’s Disease Brain

(2013) Ramasamy Thangavel et al.   NEUROCHEMICAL RESEARCH

Dynorphins regulate the strength of social memory

(2013) A. Bilkei-Gorzo et al.   NEUROPHARMACOLOGY

Novel ncRNAs transcribed by Pol III and elucidation of their functional relevance by biophysical approaches

(2013) Paola Gavazzo et al.   Frontiers in Cellular Neuroscience

The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain

(2013) Ingrid Ehrmann et al.   PLoS Genetics

Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation

(2013) Christoph Jüschke et al.   GENOME BIOLOGY

Alzheimer’s Disease And Type 2 Diabetes: Exploring The Association To Obesity And Tyrosine Hydroxylase

(2012) Medha Priyadarshini et al.   CNS & Neurological Disorders-Drug Targets

An intronic ncRNA-dependent regulation of SORL1 expression affecting A  formation is upregulated in post-mortem Alzheimer's disease brain samples

(2012) E. Ciarlo et al.   Disease Models & Mechanisms

Locus-specific mutation databases for neurodegenerative brain diseases

(2012) Marc Cruts et al.   HUMAN MUTATION

Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease

(2012) Nicole C. Berchtold et al.   NEUROBIOLOGY OF AGING

Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative

(2012) Shashwath A. Meda et al.   NEUROBIOLOGY OF AGING

Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling

(2012) Neil M. Fournier et al.   NEUROPHARMACOLOGY

RNA-interacting proteins act as site-specific repressors of ADAR2-mediated RNA editing and fluctuate upon neuronal stimulation

(2012) Aamira Tariq et al.   NUCLEIC ACIDS RESEARCH

The effect of tachykinin neuropeptides on amyloid β aggregation

(2011) Efrat Flashner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The dynorphin/κ-opioid receptor system and its role in psychiatric disorders

(2011) H. A. Tejeda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hippocampal synaptic plasticity in Alzheimer’s disease: what have we learned so far from transgenic models?

(2011) Cristina Marchetti et al.   REVIEWS IN THE NEUROSCIENCES

Regulatory RNAs in brain function and disorders

(2010) Anna Iacoangeli et al.   BRAIN RESEARCH

Rac and Rho GTPases in cancer cell motility control

(2010) Matteo Parri et al.   Cell Communication and Signaling

Role of SFRS13A in low-density lipoprotein receptor splicing

(2010) I-Fang Ling et al.   HUMAN MUTATION

MicroRNAs-10a and -10b Contribute to Retinoic Acid-induced Differentiation of Neuroblastoma Cells and Target the Alternative Splicing Regulatory Factor SFRS1 (SF2/ASF)

(2010) Salvador Meseguer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE

(2010) Rita J. Guerreiro et al.   NEUROBIOLOGY OF AGING

Increased CD44 Gene Expression in Lymphocytes Derived from Alzheimer Disease Patients

(2010) D. Uberti et al.   Neurodegenerative Diseases

Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons

(2008) R. N. Kanadia et al.   DEVELOPMENT

Translational Control by a Small RNA: Dendritic BC1 RNA Targets the Eukaryotic Initiation Factor 4A Helicase Mechanism

(2008) D. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE

Gene expression changes in the course of normal brain aging are sexually dimorphic

(2008) N. C. Berchtold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA