Unusual Placement of an EBV Epitope into the Groove of the Ankylosing Spondylitis-Associated HLA-B27 Allele Allows CD8+ T Cell Activation

Peptide trimming by endoplasmic reticulum aminopeptidases: Role of MHC class I binding and ERAP dimerization

(2019) Irini Evnouchidou et al.   HUMAN IMMUNOLOGY

The Peptide Repertoire of HLA-B27 may include Ligands with Lysine at P2 Anchor Position

(2018) Shira Yair-Sabag et al.   PROTEOMICS

An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes

(2018) Fabiana Paladini et al.   Scientific Reports

How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins

(2018) José A. López de Castro   Frontiers in Immunology

Pathogenesis of ankylosing spondylitis — recent advances and future directions

(2017) Vidya Ranganathan et al.   Nature Reviews Rheumatology

An Update on the Genetic Polymorphism of HLA-B*27 With 213 Alleles Encompassing 160 Subtypes (and Still Counting)

(2017) Muhammad A. Khan   Current Rheumatology Reports

Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens

(2017) Ziwei Xiao et al.   Scientific Reports

The Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients

(2016) Valentina Tedeschi et al.   MOLECULAR MEDICINE

The Peptidome of Behçet's Disease-Associated HLA-B*51:01 Includes Two Subpeptidomes Differentially Shaped by Endoplasmic Reticulum Aminopeptidase 1

(2016) Pablo Guasp et al.   Arthritis & Rheumatology

ERAP2is associated with ankylosing spondylitis inHLA-B27-positive andHLA-B27-negative patients

(2015) Philip C Robinson et al.   ANNALS OF THE RHEUMATIC DISEASES

Zooming into the binding groove of HLA molecules: which positions and which substitutions change peptide binding most?

(2015) Hanneke W. M. van Deutekom et al.   IMMUNOGENETICS

Genetics of ankylosing spondylitis—insights into pathogenesis

(2015) Matthew A. Brown et al.   Nature Reviews Rheumatology

Endoplasmic reticulum aminopeptidase 1 function and its pathogenic role in regulating innate and adaptive immunity in cancer and major histocompatibility complex class I-associated autoimmune diseases

(2014) D. Fruci et al.   TISSUE ANTIGENS

HLA-B27-mediated protection in HIV and hepatitis C virus infection and pathogenesis in spondyloarthritis

(2013) Christoph Neumann-Haefelin   CURRENT OPINION IN RHEUMATOLOGY

Structural and dynamic features of HLA-B27 subtypes

(2013) Barbara Uchanska-Ziegler et al.   CURRENT OPINION IN RHEUMATOLOGY

Natural HLA-B*2705 Protein Ligands with Glutamine as Anchor Motif

(2013) Susana Infantes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HLA-B27 misfolding and ankylosing spondylitis

(2013) Robert A. Colbert et al.   MOLECULAR IMMUNOLOGY

HLA-B27 and antigen presentation: At the crossroads between immune defense and autoimmunity

(2013) Rosa Sorrentino et al.   MOLECULAR IMMUNOLOGY

Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA-B27

(2013) Liye Chen et al.   Arthritis & Rheumatology

A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned

(2012) Stephanie Gras et al.   IMMUNOLOGICAL REVIEWS

GalaxyWEB server for protein structure prediction and refinement

(2012) J. Ko et al.   NUCLEIC ACIDS RESEARCH

Influence of inflammation-related changes on conformational characteristics of HLA-B27 subtypes as detected by IR spectroscopy

(2011) Heinz Fabian et al.   FEBS Journal

Dynamical Characterization of Two Differentially Disease Associated MHC Class I Proteins in Complex with Viral and Self-Peptides

(2011) Daniele Narzi et al.   JOURNAL OF MOLECULAR BIOLOGY

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Running the gauntlet: from peptide generation to antigen presentation by MHC class I

(2011) P. M. Saunders et al.   TISSUE ANTIGENS

HLA-B27 heavy chains distinguished by a micropolymorphism exhibit differential flexibility

(2010) Heinz Fabian et al.   ARTHRITIS AND RHEUMATISM

Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

(2010) Andrej Košmrlj et al.   NATURE

Peptides: the cornerstone of HLA-B27 biology and pathogenetic role in spondyloarthritis

(2008) M. Marcilla et al.   TISSUE ANTIGENS

HLA-B27 Subtypes Differentially Associated with Disease Exhibit Conformational Differences in Solution

(2007) Heinz Fabian et al.   JOURNAL OF MOLECULAR BIOLOGY