Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells

Therapeutic implications of cancer epithelial-mesenchymal transition (EMT)

(2019) Eunae Sandra Cho et al.   ARCHIVES OF PHARMACAL RESEARCH

EMT and Treatment Resistance in Pancreatic Cancer

(2017) Nicola Gaianigo et al.   Cancers

Pancreatic cancer: Current research and future directions

(2016) Marco Falasca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

TUFT1 regulates metastasis of pancreatic cancer through HIF1-Snail pathway induced epithelial–mesenchymal transition

(2016) Bin Zhou et al.   CANCER LETTERS

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation

(2016) Miguel C. Lucena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion

(2016) Brian Cunniff et al.   MOLECULAR BIOLOGY OF THE CELL

Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program

(2016) Esther Aguilar et al.   STEM CELLS

Epithelial–mesenchymal transition induces similar metabolic alterations in two independent breast cancer cell lines

(2015) Yuvabharath Kondaveeti et al.   CANCER LETTERS

Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein

(2015) J. J. Kamphorst et al.   CANCER RESEARCH

Pancreatic cancer: The microenvironment needs attention too!

(2015) M.V. Apte et al.   PANCREATOLOGY

RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma

(2015) Runze Shang et al.   TUMOR BIOLOGY

Loss of polarity protein AF6 promotes pancreatic cancer metastasis by inducing Snail expression

(2015) Yi Xu et al.   Nature Communications

Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up

(2015) R. M. Perera et al.   Cancer Discovery

Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells

(2015) Takumi Shiraishi et al.   Oncotarget

Acid-Mediated Tumor Proteolysis: Contribution of Cysteine Cathepsins

(2015) Jennifer M Rothberg et al.   NEOPLASIA

Movers and shakers: cell cytoskeleton in cancer metastasis

(2014) C M Fife et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dihydropyrimidine Accumulation Is Required for the Epithelial-Mesenchymal Transition

(2014) Yoav D. Shaul et al.   CELL

Gemcitabine Resistance is Associated with Epithelial-Mesenchymal Transition and Induction of HIF-1α in Pancreatic Cancer Cells

(2014) Rui Wang et al.   CURRENT CANCER DRUG TARGETS

Fatty Acid Synthase Mediates the Epithelial-Mesenchymal Transition of Breast Cancer Cells

(2014) Junqin Li et al.   International Journal of Biological Sciences

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

(2014) Valerie S. LeBleu et al.   NATURE CELL BIOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

(2014) L Jiang et al.   ONCOGENE

Snail Contributes to the Maintenance of Stem Cell-Like Phenotype Cells in Human Pancreatic Cancer

(2014) Wei Zhou et al.   PLoS One

Tumor Macroenvironment and Metabolism

(2014) Wael Al-Zhoughbi et al.   SEMINARS IN ONCOLOGY

Loss of SNAIL inhibits cellular growth and metabolism through the miR-128-mediated RPS6KB1/HIF-1α/PKM2 signaling pathway in prostate cancer cells

(2014) Tao Tao et al.   TUMOR BIOLOGY

Metabolism addiction in pancreatic cancer

(2014) R Blum et al.   Cell Death & Disease

Snail modulates cell metabolism in MDCK cells

(2013) Misako Haraguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer

(2013) Chenfang Dong et al.   CANCER CELL

Decreased TIP30 expression predicts poor prognosis in pancreatic cancer patients

(2013) Shiwei Guo et al.   INTERNATIONAL JOURNAL OF CANCER

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Epithelial-Mesenchymal Transition Stimulates Human Cancer Cells to Extend Microtubule-based Invasive Protrusions and Suppresses Cell Growth in Collagen Gel

(2013) Jun Oyanagi et al.   PLoS One

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

(2013) J. J. Kamphorst et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How does cancer cell metabolism affect tumor migration and invasion?

(2013) Tianyu Han et al.   Cell Adhesion & Migration

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Wnt/Snail Signaling Regulates Cytochrome c Oxidase and Glucose Metabolism

(2012) S. Y. Lee et al.   CANCER RESEARCH

Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay

(2012) T. Fiaschi et al.   CANCER RESEARCH

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy

(2012) Chin-Chih Lin et al.   Scientific Reports

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release

(2011) Kristina Goetze   INTERNATIONAL JOURNAL OF ONCOLOGY

Pancreatic Cancer Cells Respond to Type I Collagen by Inducing Snail Expression to Promote Membrane Type 1 Matrix Metalloproteinase-dependent Collagen Invasion

(2011) Mario A. Shields et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo

(2010) Ryohei Nishioka et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Increased 18F-FDG uptake and expression of Glut1 in the EMT transformed breast cancer cells induced by TGF-β

(2010) W. Li et al.   NEOPLASMA

Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent: Potent Tissue-Specific Effects of Medium-Chain Fatty Acids

(2009) N. Turner et al.   DIABETES

E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex

(2009) Johannes von Burstin et al.   GASTROENTEROLOGY

OpenFLUX: efficient modelling software for 13C-based metabolic flux analysis

(2009) Lake-Ee Quek et al.   Microbial Cell Factories

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

(2009) Athanasia Spandidos et al.   NUCLEIC ACIDS RESEARCH