SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player

β-Nicotinamide Adenine Dinucleotide (β-NAD) Inhibits ATP-Dependent IL-1β Release from Human Monocytic Cells

(2018) Sebastian Hiller et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation

(2018) Carlo Marchetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond the Channel: Metabotropic Signaling by Nicotinic Receptors

(2018) Nadine Kabbani et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The cardioprotective effects of secretory leukocyte protease inhibitor against myocardial ischemia/reperfusion injury

(2018) Eakkapote Prompunt et al.   Experimental and Therapeutic Medicine

The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

(2018) Luiz E. B. Savio et al.   Frontiers in Pharmacology

Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors

(2018) Kathrin Siebers et al.   Frontiers in Immunology

C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation

(2018) Katrin Richter et al.   Frontiers in Immunology

The P2X7 Receptor in Infection and Inflammation

(2017) Francesco Di Virgilio et al.   IMMUNITY

Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors

(2017) Sören Backhaus et al.   JOURNAL OF LIPID RESEARCH

Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1β by Monocytic Cells

(2017) Anca-Laura Amati et al.   MEDIATORS OF INFLAMMATION

Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

(2017) Haylie K. Romero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10

(2017) Anna Zakrzewicz et al.   Frontiers in Cellular Neuroscience

A G protein-coupled α7 nicotinic receptor regulates signaling and TNF-α release in microglia

(2017) Justin R. King et al.   FEBS Open Bio

iPLA2β deficiency attenuates obesity and hepatic steatosis in ob / ob mice through hepatic fatty-acyl phospholipid remodeling

(2016) Xiuling Deng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphocholine – an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors

(2016) K. Richter et al.   Scientific Reports

Identification and Characterization of a G Protein-binding Cluster in α7 Nicotinic Acetylcholine Receptors

(2015) Justin R. King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release

(2015) Andreas Hecker et al.   JOURNAL OF IMMUNOLOGY

Calcium-independent phospholipases A2and their roles in biological processes and diseases

(2015) Sasanka Ramanadham et al.   JOURNAL OF LIPID RESEARCH

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Natural Compounds Interacting with Nicotinic Acetylcholine Receptors: From Low-Molecular Weight Ones to Peptides and Proteins

(2015) Denis Kudryavtsev et al.   Toxins

Are nicotinic acetylcholine receptors coupled to G proteins?

(2013) Nadine Kabbani et al.   BIOESSAYS

Inflammasomes and host defenses against bacterial infections

(2013) Gregory I Vladimer et al.   CURRENT OPINION IN MICROBIOLOGY

Annexin A2 Heterotetramer: Structure and Function

(2013) Alamelu Bharadwaj et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SLPI and elafin: multifunctional antiproteases of the WFDC family

(2012) Aaron Scott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

The Nicotinic Acetylcholine Receptor as a Target for Antidepressant Drug Development

(2012) Noah S. Philip et al.   TheScientificWorldJOURNAL

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Secretory Leukocyte Protease Inhibitor Plays an Important Role in the Regulation of Allergic Asthma in Mice

(2011) Rafael Marino et al.   JOURNAL OF IMMUNOLOGY

Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet

(2011) Venkata J Adapala et al.   Journal of Inflammation-London

C terminus of the P2X7 receptor: treasure hunting

(2011) Helio Miranda Costa-Junior et al.   Purinergic Signalling

Alpha9 nicotinic acetylcholine receptors and the treatment of pain

(2009) J. Michael McIntosh et al.   BIOCHEMICAL PHARMACOLOGY

Secretory leukocyte peptidase inhibitor and lung cancer

(2008) Toshihiro Nukiwa et al.   CANCER SCIENCE

Phospholipase A2 Biochemistry

(2008) John E. Burke et al.   CARDIOVASCULAR DRUGS AND THERAPY

 Conotoxin Arenatus IB[V11L,V16D] Is a Potent and Selective Antagonist at Rat and Human Native  7 Nicotinic Acetylcholine Receptors

(2008) N. Innocent et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Multifaceted roles of human elafin and secretory leukocyte proteinase inhibitor (SLPI), two serine protease inhibitors of the chelonianin family

(2007) Thierry Moreau et al.   BIOCHIMIE