Metabolism of Stem and Progenitor Cells: Proper Methods to Answer Specific Questions

Environmental enrichment, new neurons and the neurobiology of individuality

(2019) Gerd Kempermann   NATURE REVIEWS NEUROSCIENCE

Metabolomics and Isotope Tracing

(2018) Cholsoon Jang et al.   CELL

Energy Producing Metabolic Pathways in Functional Regulation of the Hematopoietic Stem Cells

(2018) Irene M. Roy et al.   IUBMB LIFE

Metabolic profiling of isolated mitochondria and cytoplasm reveals compartment-specific metabolic responses

(2018) Daqiang Pan et al.   Metabolomics

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system

(2018) Moe Watanabe et al.   Molecular Pain

Metabolism as master of hematopoietic stem cell fate

(2018) Kyoko Ito et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Non-Canonical Control of Neuronal Energy Status by the Na+ Pump

(2018) Felipe Baeza-Lehnert et al.   Cell Metabolism

Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0

(2018) Ian Law et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Amino acid supplements and metabolic health: a potential interplay between intestinal microbiota and systems control

(2017) Francesco Bifari et al.   Genes and Nutrition

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

(2017) Rachel L. Wolfson et al.   NATURE

Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation

(2017) Brittney A Beyer et al.   Nature Chemical Biology

Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis

(2017) Ruth Beckervordersandforth et al.   NEURON

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

(2017) Monther Abu-Remaileh et al.   SCIENCE

Monitoring ATP dynamics in electrically active white matter tracts

(2017) Andrea Trevisiol et al.   eLife

High Yield of Adult Oligodendrocyte Lineage Cells Obtained from Meningeal Biopsy

(2017) Sissi Dolci et al.   Frontiers in Pharmacology

Amino acid supplements and metabolic health: a potential interplay between intestinal microbiota and systems control

(2017) Francesco Bifari et al.   Genes and Nutrition

Cytosolic NADH-NAD+ Redox Visualized in Brain Slices by Two-Photon Fluorescence Lifetime Biosensor Imaging

(2016) Rebecca Mongeon et al.   ANTIOXIDANTS & REDOX SIGNALING

The great importance of normalization of LC-MS data for highly-accurate non-targeted metabolomics

(2016) Hajime Mizuno et al.   BIOMEDICAL CHROMATOGRAPHY

Branched-chain amino acids differently modulate catabolic and anabolic states in mammals: a pharmacological point of view

(2016) Francesco Bifari et al.   BRITISH JOURNAL OF PHARMACOLOGY

In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

(2016) Philipp Mächler et al.   Cell Metabolism

Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism

(2016) Annelies Quaegebeur et al.   Cell Metabolism

Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State

(2016) Wen Gu et al.   Cell Stem Cell

Hematopoietic stem cell lineage specification

(2016) Marie Pouzolles et al.   CURRENT OPINION IN HEMATOLOGY

Metabolic regulation of hematopoietic stem cell commitment and erythroid differentiation

(2016) Leal Oburoglu et al.   CURRENT OPINION IN HEMATOLOGY

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

(2016) Christian Lange et al.   EMBO JOURNAL

Mechanistic roles of autophagy in hematopoietic differentiation

(2016) Thomas Riffelmacher et al.   FEBS Journal

Separation and quantification of lactate and lipid at 1.3 ppm by diffusion-weighted magnetic resonance spectroscopy

(2016) Anna M. Wang et al.   MAGNETIC RESONANCE IN MEDICINE

Biosynthesis of glycerol phosphate is associated with long-term potentiation in hippocampal neurons

(2016) Giuseppe Martano et al.   Metabolomics

Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential

(2016) Larry L. Luchsinger et al.   NATURE

Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing

(2016) Navdeep S. Chandel et al.   NATURE CELL BIOLOGY

Atmospheric pressure MALDI mass spectrometry imaging of tissues and cells at 1.4-μm lateral resolution

(2016) Mario Kompauer et al.   NATURE METHODS

Funnel-freezing versus heat-stabilization for the visualization of metabolites by mass spectrometry imaging in a mouse stroke mode l

(2016) Inge A. Mulder et al.   PROTEOMICS

Energy metabolism in the acquisition and maintenance of stemness

(2016) Clifford D.L. Folmes et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

(2016) Nicola Vannini et al.   Nature Communications

Positron Emission Tomography Imaging of Tumor Cell Metabolism and Application to Therapy Response Monitoring

(2016) Amarnath Challapalli et al.   Frontiers in Oncology

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency

(2015) Yasuyuki S. Kida et al.   Cell Stem Cell

Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

(2015) Allison M. Bond et al.   Cell Stem Cell

Metabolic restructuring and cell fate conversion

(2015) Alessandro Prigione et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Radiopharmaceuticals as probes to characterize tumour tissue

(2015) Israt S. Alam et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

(2015) Henrik Sperber et al.   NATURE CELL BIOLOGY

Highest Resolution In Vivo Human Brain MRI Using Prospective Motion Correction

(2015) Daniel Stucht et al.   PLoS One

NH4+ triggers the release of astrocytic lactate via mitochondrial pyruvate shunting

(2015) Rodrigo Lerchundi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

(2015) R. A. Saxton et al.   SCIENCE

Meninges harbor cells expressing neural precursor markers during development and adulthood

(2015) Francesco Bifari et al.   Frontiers in Cellular Neuroscience

Validation and application of sub-2 μm core–shell UHPLC–UV–ESI–Orbitrap MS for identification and quantification of β-carotene and selected cleavage products with preceding solid-phase extraction

(2014) G. Martano et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Patch Clamp Electrophysiology and Capillary Electrophoresis–Mass Spectrometry Metabolomics for Single Cell Characterization

(2014) Jordan T. Aerts et al.   ANALYTICAL CHEMISTRY

A Novel Radiotracer to Image Glycogen Metabolism in Tumors by Positron Emission Tomography

(2014) T. H. Witney et al.   CANCER RESEARCH

Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells

(2014) Nobuaki Shiraki et al.   Cell Metabolism

Imaging biomarkers in primary brain tumours

(2014) Egesta Lopci et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Fast sampling method for mammalian cell metabolic analyses using liquid chromatography–mass spectrometry

(2014) Giuseppe Martano et al.   Nature Protocols

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

(2014) Joshua K Salabei et al.   Nature Protocols

Metabolic requirements for the maintenance of self-renewing stem cells

(2014) Keisuke Ito et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Imaging Mitochondrial Flux in Single Cells with a FRET Sensor for Pyruvate

(2014) Alejandro San Martín et al.   PLoS One

Noninvasive positron emission tomography and fluorescence imaging of CD133+tumor stem cells

(2014) Simone Gaedicke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Stem cell metabolism in tissue development and aging

(2013) N. Shyh-Chang et al.   DEVELOPMENT

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

Nutrient-sensing pathways and metabolic regulation in stem cells

(2013) Joshua D. Ochocki et al.   JOURNAL OF CELL BIOLOGY

Nutrient Sensing, Metabolism, and Cell Growth Control

(2013) Hai-Xin Yuan et al.   MOLECULAR CELL

Understanding Metabolic Regulation and Its Influence on Cell Physiology

(2013) Christian M. Metallo et al.   MOLECULAR CELL

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry

(2013) Peter Nemes et al.   Nature Protocols

Single-Cell Metabolomics: Analytical and Biological Perspectives

(2013) R. Zenobi   SCIENCE

Mitochondrial DNA Haplotypes Define Gene Expression Patterns in Pluripotent and Differentiating Embryonic Stem Cells

(2013) Richard D.W. Kelly et al.   STEM CELLS

Imaging energy status in live cells with a fluorescent biosensor of the intracellular ATP-to-ADP ratio

(2013) Mathew Tantama et al.   Nature Communications

MicroPET/SPECT/CT Imaging of Small Animal Models of Disease

(2012) Wade Koba et al.   AMERICAN JOURNAL OF PATHOLOGY

Metabolic Regulation of Epigenetics

(2012) Chao Lu et al.   Cell Metabolism

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Neural Stem Cell Niches in Health and Diseases

(2012) Ilaria Decimo et al.   CURRENT PHARMACEUTICAL DESIGN

Advances in multimodal neuroimaging: Hybrid MR–PET and MR–PET–EEG at 3T and 9.4T

(2012) N. Jon Shah et al.   JOURNAL OF MAGNETIC RESONANCE

2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas

(2012) Changho Choi et al.   NATURE MEDICINE

Human Embryonic Stem Cells and Embryonal Carcinoma Cells Have Overlapping and Distinct Metabolic Signatures

(2012) Raed Abu Dawud et al.   PLoS One

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor

(2011) Yin Pun Hung et al.   Cell Metabolism

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

(2011) Clifford D.L. Folmes et al.   Cell Metabolism

Fast liquid chromatography: The domination of core?shell and very fine particles

(2011) Szabolcs Fekete et al.   JOURNAL OF CHROMATOGRAPHY A

Noninvasive stem cell tracking

(2011) Frank M. Bengel   JOURNAL OF NUCLEAR CARDIOLOGY

Nestin- and Doublecortin-Positive Cells Reside in Adult Spinal Cord Meninges and Participate in Injury-Induced Parenchymal Reaction

(2011) Ilaria Decimo et al.   STEM CELLS

Patterns of Amino Acid Metabolism by Proliferating Human Mesenchymal Stem Cells

(2011) Gustavo A. Higuera et al.   TISSUE ENGINEERING PART A

Guidelines for the labelling of leucocytes with 99mTc-HMPAO

(2010) Erik F. J. de Vries et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The Kennedy pathway-De novo synthesis of phosphatidylethanolamine and phosphatidylcholine

(2010) Federica Gibellini et al.   IUBMB LIFE

Nicotine increases the expression of neurotrophin receptor tyrosine kinase receptor A in basal forebrain cholinergic neurons

(2010) E. Formaggio et al.   NEUROSCIENCE

In Vivo MRI Cell Tracking: Clinical Studies

(2009) Jeff W. M. Bulte   AMERICAN JOURNAL OF ROENTGENOLOGY

Molecular imaging in neuroendocrine tumors: Molecular uptake mechanisms and clinical results

(2009) Klaas P. Koopmans et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Visualizing cancer and immune cell function with metabolic positron emission tomography

(2009) Rachel E Laing et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Novel stem/progenitor cells with neuronal differentiation potential reside in the leptomeningeal niche

(2009) Francesco Bifari et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A genetically encoded fluorescent reporter of ATP:ADP ratio

(2009) Jim Berg et al.   NATURE METHODS

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effective Quenching Processes for Physiologically Valid Metabolite Profiling of Suspension Cultured Mammalian Cells

(2008) Christopher A. Sellick et al.   ANALYTICAL CHEMISTRY

Carbonic anhydrase IX and renal cell carcinoma: prognosis, response to systemic therapy, and future vaccine strategies

(2008) Brian Shuch et al.   BJU INTERNATIONAL

Erythrocyte Glut1 Triggers Dehydroascorbic Acid Uptake in Mammals Unable to Synthesize Vitamin C

(2008) Amélie Montel-Hagen et al.   CELL

Tissue characterization of glioma by proton magnetic resonance spectroscopy and perfusion-weighted magnetic resonance imaging: glioma grading and histological correlation

(2008) Mariko Toyooka et al.   CLINICAL IMAGING

TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

(2008) Chong Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Live single-cell video-mass spectrometry for cellular and subcellular molecular detection and cell classification

(2008) Hajime Mizuno et al.   JOURNAL OF MASS SPECTROMETRY

Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach

(2008) Bryson D Bennett et al.   Nature Protocols

Kinetic flux profiling for quantitation of cellular metabolic fluxes

(2008) Jie Yuan et al.   Nature Protocols