Differential Neuroinflammatory Response in Male and Female Mice: A Role for BDNF

Antidepressant activity of vorinostat is associated with amelioration of oxidative stress and inflammation in a corticosterone-induced chronic stress model in mice

(2018) Athira KV et al.   BEHAVIOURAL BRAIN RESEARCH

Chronic Stress Exposure Reduces Parvalbumin Expression in the Rat Hippocampus through an Imbalance of Redox Mechanisms: Restorative Effect of the Antipsychotic Lurasidone

(2018) Andrea C Rossetti et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats

(2018) Ya-Lin Wang et al.   Journal of Neuroinflammation

Regulatory Effects of Neuroinflammatory Responses Through Brain-Derived Neurotrophic Factor Signaling in Microglial Cells

(2018) Sheng-Wei Lai et al.   MOLECULAR NEUROBIOLOGY

Sex differences and the neurobiology of affective disorders

(2018) David R. Rubinow et al.   NEUROPSYCHOPHARMACOLOGY

Sex differences in antidepressant efficacy

(2018) Tara A. LeGates et al.   NEUROPSYCHOPHARMACOLOGY

Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan

(2018) Tuan Leng Tay et al.   Frontiers in Molecular Neuroscience

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

(2018) Bruno Lima Giacobbo et al.   MOLECULAR NEUROBIOLOGY

Transcriptional and Translational Differences of Microglia from Male and Female Brains

(2018) Dilansu Guneykaya et al.   Cell Reports

Sertraline ameliorates inflammation in CUMS mice and inhibits TNF-α-induced inflammation in microglia cells

(2018) Ying Lu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity

(2017) Richa Hanamsagar et al.   GLIA

Pathophysiological mechanisms involved in the relationship between diabetes and major depressive disorder

(2017) Gislaine Z. Réus et al.   LIFE SCIENCES

Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

(2017) Eero Castrén et al.   NEUROBIOLOGY OF DISEASE

Genome-wide analysis of LPS-induced inflammatory response in the rat ventral hippocampus: Modulatory activity of the antidepressant agomelatine

(2017) Andrea Carlo Rossetti et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

To Group or Not to Group? Good Practice for Housing Male Laboratory Mice

(2017) Sarah Kappel et al.   Animals

Immunology of Major Depression

(2017) Norbert Müller   NEUROIMMUNOMODULATION

Age and sex differences in immune response following LPS treatment in mice

(2016) Kyle Chiman Cai et al.   BRAIN BEHAVIOR AND IMMUNITY

Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

(2016) Yvonne Couch et al.   Journal of Neuroinflammation

Sex differences in brain-derived neurotrophic factor signaling: Functions and implications

(2016) Yi-Chao Wei et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Sex differences in brain-derived neurotrophic factor signaling and functions

(2016) Chi Bun Chan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Stress-induced anhedonia is associated with the activation of the inflammatory system in the rat brain: Restorative effect of pharmacological intervention

(2016) Andrea C. Rossetti et al.   PHARMACOLOGICAL RESEARCH

Major depressive disorder

(2016) Christian Otte et al.   Nature Reviews Disease Primers

The transcription factor nuclear factor interleukin 6 mediates pro- and anti-inflammatory responses during LPS-induced systemic inflammation in mice

(2015) Jenny Schneiders et al.   BRAIN BEHAVIOR AND IMMUNITY

Immune dysregulation and cognitive vulnerability in the aging brain: Interactions of microglia, IL-1β, BDNF and synaptic plasticity

(2015) Susan L. Patterson   NEUROPHARMACOLOGY

Gender and brain regions specific differences in brain derived neurotrophic factor protein levels of depressed individuals who died through suicide

(2015) Shawn Hayley et al.   NEUROSCIENCE LETTERS

Comorbidity between Type 2 Diabetes and Depression in the Adult Population: Directions of the Association and Its Possible Pathophysiological Mechanisms

(2015) Line Iden Berge et al.   International Journal of Endocrinology

Sex Differences in Depression: Does Inflammation Play a Role?

(2015) Heather M. Derry et al.   Current Psychiatry Reports

Estrogen accelerates the resolution of inflammation in macrophagic cells

(2015) Alessandro Villa et al.   Scientific Reports

A Starring Role for Microglia in Brain Sex Differences

(2014) Kathryn M. Lenz et al.   NEUROSCIENTIST

Inhibition of IL-6 family cytokines by SOCS3

(2014) Jeffrey J. Babon et al.   SEMINARS IN IMMUNOLOGY

Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity

(2014) Francesca Calabrese et al.   Frontiers in Cellular Neuroscience

Fractalkine regulation of microglial physiology and consequences on the brain and behavior

(2014) Rosa Chiara Paolicelli et al.   Frontiers in Cellular Neuroscience

Microglial activation, increased TNF and SERT expression in the prefrontal cortex define stress-altered behaviour in mice susceptible to anhedonia

(2013) Yvonne Couch et al.   BRAIN BEHAVIOR AND IMMUNITY

Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine

(2013) Raffaella Molteni et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Altered inflammatory responsiveness in serotonin transporter mutant rats

(2013) Flavia Macchi et al.   Journal of Neuroinflammation

Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484)

(2013) M L Molendijk et al.   MOLECULAR PSYCHIATRY

Brain-Derived Neurotrophic Factor Serum Levels and Genotype: Association with Depression during Interferon-α Treatment

(2013) Francis E Lotrich et al.   NEUROPSYCHOPHARMACOLOGY

Microglia, seen from the CX3CR1 angle

(2013) Yochai Wolf et al.   Frontiers in Cellular Neuroscience

Microglia Control Neuronal Network Excitability via BDNF Signalling

(2013) Francesco Ferrini et al.   NEURAL PLASTICITY

Interferon-Induced Depression in Chronic Hepatitis C

(2012) Marc Udina et al.   JOURNAL OF CLINICAL PSYCHIATRY

The impact of environmental enrichment on sex-specific neurochemical circuitries – Effects on brain-derived neurotrophic factor and the serotonergic system

(2012) S. Chourbaji et al.   NEUROSCIENCE

Cross-national epidemiology of DSM-IV major depressive episode

(2011) Evelyn Bromet et al.   BMC Medicine

Sex-dependent and region-specific changes in TrkB signaling in BDNF heterozygous mice

(2011) Rachel A. Hill et al.   BRAIN RESEARCH

Effect of Population Heterogenization on the Reproducibility of Mouse Behavior: A Multi-Laboratory Study

(2011) S. Helene Richter et al.   PLoS One

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Depressive symptoms following interferon-α therapy: mediated by immune-induced reductions in brain-derived neurotrophic factor?

(2010) Gunter Kenis et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Altering BDNF expression by genetics and/or environment: Impact for emotional and depression-like behaviour in laboratory mice

(2010) Sabine Chourbaji et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Sex-differential modulation of visceral pain by brain derived neurotrophic factor (BDNF) in rats

(2010) Fang Li et al.   NEUROSCIENCE LETTERS

A Meta-Analysis of Cytokines in Major Depression

(2009) Yekta Dowlati et al.   BIOLOGICAL PSYCHIATRY

Estrogen Masculinizes Neural Pathways and Sex-Specific Behaviors

(2009) Melody V. Wu et al.   CELL

Tumor necrosis factor-α augments lipopolysaccharide-induced suppressor of cytokine signalling 3 (SOCS-3) protein expression by preventing the degradation

(2009) Jargalsaikhan Dagvadorj et al.   IMMUNOLOGY

Brain-Derived Neurotrophic Factor Induces Sustained Elevation of Intracellular Ca2+ in Rodent Microglia

(2009) Y. Mizoguchi et al.   JOURNAL OF IMMUNOLOGY

Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis

(2009) M Bryant Howren et al.   PSYCHOSOMATIC MEDICINE

Activation of Central Nervous System Inflammatory Pathways by Interferon-Alpha: Relationship to Monoamines and Depression

(2008) Charles L. Raison et al.   BIOLOGICAL PSYCHIATRY

Estrogen anti-inflammatory activity in brain: A therapeutic opportunity for menopause and neurodegenerative diseases

(2008) Elisabetta Vegeto et al.   FRONTIERS IN NEUROENDOCRINOLOGY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE