Sex differences in brain-derived neurotrophic factor signaling: Functions and implications

Higher brainBDNFgene expression is associated with slower cognitive decline in older adults

(2016) Aron S. Buchman et al.   NEUROLOGY

Sex-dependent and independent effects of long-term voluntary wheel running on Bdnf mRNA and protein expression

(2016) Andrew C. Venezia et al.   PHYSIOLOGY & BEHAVIOR

Epigenetics and sex differences in the brain: A genome-wide comparison of histone-3 lysine-4 trimethylation (H3K4me3) in male and female mice

(2015) Erica Y. Shen et al.   EXPERIMENTAL NEUROLOGY

Sex and age differences in brain-derived neurotrophic factor and vimentin in the zebra finch song system: Relationships to newly generated cells

(2015) Yu Ping Tang et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Brain feminization requires active repression of masculinization via DNA methylation

(2015) Bridget M Nugent et al.   NATURE NEUROSCIENCE

Sex Influences on the Brain: An Issue Whose Time Has Come

(2015) Larry Cahill et al.   NEURON

Sex differences in depression-like behavior after nerve injury are associated with differential changes in brain-derived neurotrophic factor levels in mice subjected to early life stress

(2015) Takashi Nishinaka et al.   NEUROSCIENCE LETTERS

Voluntary exercise decreases ethanol preference and consumption in C57BL/6 adolescent mice: Sex differences and hippocampal BDNF expression

(2015) X. Gallego et al.   PHYSIOLOGY & BEHAVIOR

At the frontier of epigenetics of brain sex differences

(2015) Margaret M. McCarthy et al.   Frontiers in Behavioral Neuroscience

Mice lacking TrkB in parvalbumin-positive cells exhibit sexually dimorphic behavioral phenotypes

(2014) Elizabeth K. Lucas et al.   BEHAVIOURAL BRAIN RESEARCH

Sex differences in Alzheimer's disease risk: are we looking at the wrong hormones?

(2014) Cynthia A. Munro   INTERNATIONAL PSYCHOGERIATRICS

Brain-Derived Neurotrophic Factor in Alzheimer’s Disease: Risk, Mechanisms, and Therapy

(2014) Jing-Hui Song et al.   MOLECULAR NEUROBIOLOGY

Early Paternal Deprivation Alters Levels of Hippocampal Brain-Derived Neurotrophic Factor and Glucocorticoid Receptor and Serum Corticosterone and Adrenocorticotropin in a Sex-Specific Way in Socially Monogamous Mandarin Voles

(2014) Ruiyong Wu et al.   NEUROENDOCRINOLOGY

Representing Sex in the Brain, One Module at a Time

(2014) Cindy F. Yang et al.   NEURON

Association of rs6265 and rs2030324 Polymorphisms in Brain-Derived Neurotrophic Factor Gene with Alzheimer’s Disease: A Meta-Analysis

(2014) Yan Lin et al.   PLoS One

Estrogenic mediation of serotonergic and neurotrophic systems: Implications for female mood disorders

(2014) Amanda P. Borrow et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Mice with altered BDNF signaling as models for mood disorders and antidepressant effects

(2014) Jesse S. O. Lindholm et al.   Frontiers in Behavioral Neuroscience

Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences

(2014) Michelle Mielke et al.   Clinical Epidemiology

Gender-related association of brain-derived neurotrophic factor gene 196A/G polymorphism with Alzheimer's disease—a meta-analysis including 6854 cases and 6868 controls

(2013) Jia Chen et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Sex-dependent alterations in BDNF-TrkB signaling in the hippocampus of reelin heterozygous mice: a role for sex steroid hormones

(2013) Rachel A. Hill et al.   JOURNAL OF NEUROCHEMISTRY

Testosterone Depletion in Adult Male Rats Increases Mossy Fiber Transmission, LTP, and Sprouting in Area CA3 of Hippocampus

(2013) V. A. Skucas et al.   JOURNAL OF NEUROSCIENCE

Activation of BDNF signaling prevents the return of fear in female mice

(2013) D. Baker-Andresen et al.   LEARNING & MEMORY

Developmental changes in BDNF protein in the song control nuclei of zebra finches

(2013) Y.P. Tang et al.   NEUROSCIENCE

Serum Brain-Derived Neurotrophic Factor and the Risk for Dementia

(2013) Galit Weinstein et al.   JAMA Neurology

Variant Brain-Derived Neurotrophic Factor (Valine66Methionine) Polymorphism Contributes to Developmental and Estrous Stage-Specific Expression of Anxiety-Like Behavior in Female Mice

(2012) Kevin G. Bath et al.   BIOLOGICAL PSYCHIATRY

Modular Genetic Control of Sexually Dimorphic Behaviors

(2012) Xiaohong Xu et al.   CELL

A Half-Truth Is a Whole Lie: On the Necessity of Investigating Sex Influences on the Brain

(2012) Larry Cahill   ENDOCRINOLOGY

Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice

(2012) Ingrid Reverte et al.   EXPERIMENTAL NEUROLOGY

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons

(2012) Sandra Dieni et al.   JOURNAL OF CELL BIOLOGY

Interaction of Sex Steroid Hormones and Brain-Derived Neurotrophic Factor-Tyrosine Kinase B Signalling: Relevance to Schizophrenia and Depression

(2012) R. A. Hill   JOURNAL OF NEUROENDOCRINOLOGY

Epigenetic inheritance of a cocaine-resistance phenotype

(2012) Fair M Vassoler et al.   NATURE NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

With a little help from my friends: Androgens tap BDNF signaling pathways to alter neural circuits

(2012) E.N. Ottem et al.   NEUROSCIENCE

Sex differences and the role of estrogen in animal models of schizophrenia: Interaction with BDNF

(2012) Y.C. Wu et al.   NEUROSCIENCE

Mechanisms underlying the interactions between rapid estrogenic and BDNF control of synaptic connectivity

(2012) D.P. Srivastava et al.   NEUROSCIENCE

Testosterone and brain-derived neurotrophic factor interactions in the avian song control system

(2012) E.A. Brenowitz   NEUROSCIENCE

Brain-derived neurotrophic factor and androgen interactions in spinal neuromuscular systems

(2012) T. Verhovshek et al.   NEUROSCIENCE

Brain-derived neurotrophic factor and glucocorticoids: Reciprocal influence on the central nervous system

(2012) T. Numakawa et al.   NEUROSCIENCE

Brain-derived neurotrophic factor–estrogen interactions in the hippocampal mossy fiber pathway: Implications for normal brain function and disease

(2012) L.C. Harte-Hargrove et al.   NEUROSCIENCE

17β-Estradiol Regulates the Sexually Dimorphic Expression of BDNF and TrkB Proteins in the Song System of Juvenile Zebra Finches

(2012) Yu Ping Tang et al.   PLoS One

Sexually Dimorphic BDNF Signaling Directs Sensory Innervation of the Mammary Gland

(2012) Y. Liu et al.   SCIENCE

17β-Estradiol replacement in young, adult and middle-aged female ovariectomized rats promotes improvement of spatial reference memory and an antidepressant effect and alters monoamines and BDNF levels in memory- and depression-related brain areas

(2011) Ágata Kiss et al.   BEHAVIOURAL BRAIN RESEARCH

Trophic Effects of Brain-Derived Neurotrophic Factor Blockade in an Androgen-Sensitive Neuromuscular System

(2010) Tom Verhovshek et al.   ENDOCRINOLOGY

Differential expression and regulation of brain-derived neurotrophic factor (BDNF) mRNA isoforms in androgen-sensitive motoneurons of the rat lumbar spinal cord

(2010) Erich N. Ottem et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)

(2010) A. G. Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gender-Specific Impact of Brain-Derived Neurotrophic Factor Signaling on Stress-Induced Depression-Like Behavior

(2009) Anita E. Autry et al.   BIOLOGICAL PSYCHIATRY

Estrogen Masculinizes Neural Pathways and Sex-Specific Behaviors

(2009) Melody V. Wu et al.   CELL

Androgen Regulates Brain-Derived Neurotrophic Factor in Spinal Motoneurons and Their Target Musculature

(2009) Tom Verhovshek et al.   ENDOCRINOLOGY

Gender differences in the enhanced vulnerability of BDNF+/− mice to mild stress

(2009) Tushar Advani et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Pro-BDNF–induced synaptic depression and retraction at developing neuromuscular synapses

(2009) Feng Yang et al.   JOURNAL OF CELL BIOLOGY

The Role of Neurotrophins in the Seasonal-Like Growth of the Avian Song Control System

(2009) A. M. Wissman et al.   JOURNAL OF NEUROSCIENCE

The Epigenetics of Sex Differences in the Brain

(2009) M. M. McCarthy et al.   JOURNAL OF NEUROSCIENCE

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

Control of extracellular cleavage of ProBDNF by high frequency neuronal activity

(2009) G. Nagappan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation

(2009) C. Chiaruttini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

Distinct subcellular localization of BDNF transcripts in cultured hypothalamic neurons and modification by neuronal activation

(2008) Esteban Enrique Aliaga et al.   JOURNAL OF NEURAL TRANSMISSION

Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory

(2008) F. D. Lubin et al.   JOURNAL OF NEUROSCIENCE

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

(2008) Tomoya Matsumoto et al.   NATURE NEUROSCIENCE