Sex differences in brain-derived neurotrophic factor signaling and functions

Cellular and molecular mechanisms of sexual differentiation in the mammalian nervous system

(2016) Nancy G. Forger et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Activation of Muscular TrkB by its Small Molecular Agonist 7,8-Dihydroxyflavone Sex-Dependently Regulates Energy Metabolism in Diet-Induced Obese Mice

(2015) Chi Bun Chan et al.   CHEMISTRY & BIOLOGY

Sex-related difference in food-anticipatory activity of mice

(2015) Zhigang Li et al.   HORMONES AND BEHAVIOR

Gender and brain regions specific differences in brain derived neurotrophic factor protein levels of depressed individuals who died through suicide

(2015) Shawn Hayley et al.   NEUROSCIENCE LETTERS

Analyzing the influence of BDNF heterozygosity on spatial memory response to 17β-estradiol

(2015) Y W C Wu et al.   Translational Psychiatry

The influence of infant–caregiver experiences on amygdala Bdnf, OXTr, and NPY expression in developing and adult male and female rats

(2014) Kathryn T. Hill et al.   BEHAVIOURAL BRAIN RESEARCH

Testosterone enhances functional recovery after stroke through promotion of antioxidant defenses, BDNF levels and neurogenesis in male rats

(2014) Hamed Fanaei et al.   BRAIN RESEARCH

Long-term ovariectomy increases BDNF gene methylation status in mouse hippocampus

(2014) Guillermo S. Moreno-Piovano et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

A meta-analysis of sex differences in human brain structure

(2014) Amber N.V. Ruigrok et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effects of energy status and diet on Bdnf expression in the ventromedial hypothalamus of male and female rats

(2014) Xian Liu et al.   PHYSIOLOGY & BEHAVIOR

The effects of enriched environment on BDNF expression in the mouse cerebellum depending on the length of exposure

(2013) D. Vazquez-Sanroman et al.   BEHAVIOURAL BRAIN RESEARCH

TrkB Receptor Agonist 7, 8 Dihydroxyflavone Triggers Profound Gender- Dependent Neuroprotection in Mice After Perinatal Hypoxia and Ischemia

(2013) Kutluay Uluc et al.   CNS & Neurological Disorders-Drug Targets

Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease

(2013) Frank M. Longo et al.   NATURE REVIEWS DRUG DISCOVERY

Brain-Derived Neurotrophic Factor Signaling and Subgenual Anterior Cingulate Cortex Dysfunction in Major Depressive Disorder

(2012) Adam Tripp et al.   AMERICAN JOURNAL OF PSYCHIATRY

Testosterone has sublayer-specific effects on dendritic spine maturation mediated by BDNF and PSD-95 in pyramidal neurons in the hippocampus CA1 area

(2012) Meihua Li et al.   BRAIN RESEARCH

Progesterone Increases the Release of Brain-Derived Neurotrophic Factor from Glia via Progesterone Receptor Membrane Component 1 (Pgrmc1)-Dependent ERK5 Signaling

(2012) Chang Su et al.   ENDOCRINOLOGY

Central Depletion of Brain-Derived Neurotrophic Factor in Mice Results in High Bone Mass and Metabolic Phenotype

(2012) C. Camerino et al.   ENDOCRINOLOGY

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Increase in Serum Brain-Derived Neurotrophic Factor in Met Allele Carriers of the BDNF Val66Met Polymorphism Is Specific to Males

(2012) Boudewijn A.A. Bus et al.   NEUROPSYCHOBIOLOGY

Acute N-methyl-d-aspartate receptor hypofunction induced by MK801 evokes sex-specific changes in behaviors observed in open-field testing in adult male and proestrus female rats

(2012) I. Feinstein et al.   NEUROSCIENCE

Estrogen receptor-  expression in neuronal cells affects bone mass

(2012) C. Ohlsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sexually Dimorphic BDNF Signaling Directs Sensory Innervation of the Mammary Gland

(2012) Y. Liu et al.   SCIENCE

Sex-dependent and region-specific changes in TrkB signaling in BDNF heterozygous mice

(2011) Rachel A. Hill et al.   BRAIN RESEARCH

Distribution of Phosphorylated TrkB Receptor in the Mouse Hippocampal Formation Depends on Sex and Estrous Cycle Stage

(2011) J. L. Spencer-Segal et al.   JOURNAL OF NEUROSCIENCE

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

(2011) Alan H. Nagahara et al.   NATURE REVIEWS DRUG DISCOVERY

Maternal deprivation and adolescent cannabinoid exposure impact hippocampal astrocytes, CB1 receptors and brain-derived neurotrophic factor in a sexually dimorphic fashion

(2011) M. López-Gallardo et al.   NEUROSCIENCE

Estradiol acts via estrogen receptors alpha and beta on pathways important for synaptic plasticity in the mouse hippocampal formation

(2011) J.L. Spencer-Segal et al.   NEUROSCIENCE

Enduring and sex-specific effects of adolescent social isolation in rats on adult stress reactivity

(2010) Ari Weintraub et al.   BRAIN RESEARCH

Developmental Time Course of Estradiol, Testosterone, and Dihydrotestosterone Levels in Discrete Regions of Male and Female Rat Brain

(2010) Anne T. M. Konkle et al.   ENDOCRINOLOGY

Hippocampal epigenetic modification at the brain-derived neurotrophic factor gene induced by an enriched environment

(2010) Naoko Kuzumaki et al.   HIPPOCAMPUS

Maternal deprivation induces a rapid decline in circulating leptin levels and sexually dimorphic modifications in hypothalamic trophic factors and cell turnover

(2010) María-Paz Viveros et al.   HORMONES AND BEHAVIOR

Phencyclidine (PCP)-Induced Disruption in Cognitive Performance is Gender-Specific and Associated with a Reduction in Brain-Derived Neurotrophic Factor (BDNF) in Specific Regions of the Female Rat Brain

(2010) Shikha Snigdha et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Full length TrkB potentiates estrogen receptor alpha mediated transcription suggesting convergence of susceptibility pathways in schizophrenia

(2010) Jenny Wong et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Sex-differential modulation of visceral pain by brain derived neurotrophic factor (BDNF) in rats

(2010) Fang Li et al.   NEUROSCIENCE LETTERS

Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence

(2010) A. Raznahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

(2010) S.-W. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase

(2009) V. B. Matthews et al.   DIABETOLOGIA

Progesterone reverses 17β-estradiol-mediated neuroprotection and BDNF induction in cultured hippocampal slices

(2009) Claudia C. Aguirre et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Evidence for a release of brain-derived neurotrophic factor from the brain during exercise

(2009) Peter Rasmussen et al.   EXPERIMENTAL PHYSIOLOGY

The Met allele of the BDNF Val66Met polymorphism is associated with increased BDNF serum concentrations

(2009) U E Lang et al.   MOLECULAR PSYCHIATRY

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Enriched environment influences hormonal status and hippocampal brain derived neurotrophic factor in a sex dependent manner

(2009) J. Bakos et al.   NEUROSCIENCE

Maternal deprivation by early weaning increases corticosterone and decreases hippocampal BDNF and neurogenesis in mice

(2009) Takefumi Kikusui et al.   PSYCHONEUROENDOCRINOLOGY

Estrous cycle regulates activation of hippocampal Akt, LIM kinase, and neurotrophin receptors in C57BL/6 mice

(2008) J.L. Spencer et al.   NEUROSCIENCE