Homomeric and Heteromeric Aβ Species Exist in Human Brain and CSF Regardless of Alzheimer’s Disease Status and Risk Genotype

Disconnection of Frontal and Parietal Areas Contributes to Impaired Attention in Very Early Alzheimer's Disease

(2018) Susanne Neufang et al.   JOURNAL OF ALZHEIMERS DISEASE

Pharmacodynamics of Cholinesterase Inhibitors Suggests Add-on Therapy with a Low-Dose Carbamylating Inhibitor in Patients on Long-Term Treatment with Rapidly Reversible Inhibitors

(2018) Taher Darreh-Shori et al.   JOURNAL OF ALZHEIMERS DISEASE

Soluble Aβ42 Acts as Allosteric Activator of the Core Cholinergic Enzyme Choline Acetyltransferase

(2018) Amit Kumar et al.   Frontiers in Molecular Neuroscience

CSF ApoE predicts clinical progression in nondemented APOEε4 carriers

(2017) Argonde C. van Harten et al.   NEUROBIOLOGY OF AGING

Amino-Terminal β-Amyloid Antibody Blocks β-Amyloid-Mediated Inhibition of the High-Affinity Choline Transporter CHT

(2017) Leah K. Cuddy et al.   Frontiers in Molecular Neuroscience

82-kDa choline acetyltransferase and SATB1 localize to β-amyloid induced matrix attachment regions

(2016) Warren Winick-Ng et al.   Scientific Reports

Soluble Amyloid-beta Aggregates from Human Alzheimer’s Disease Brains

(2016) Thomas J. Esparza et al.   Scientific Reports

Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs

(2015) Rajnish Kumar et al.   BRAIN

Rapidly progressive Alzheimer’s disease features distinct structures of amyloid-β

(2015) Mark L. Cohen et al.   BRAIN

Efficacy of Donepezil for Cognitive Impairments in Familial Hypercholesterolemia: Preclinical Proof of Concept

(2015) Jadna Bogado Lopes et al.   CNS Neuroscience & Therapeutics

η-Secretase processing of APP inhibits neuronal activity in the hippocampus

(2015) Michael Willem et al.   NATURE

Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation

(2014) Linn Malmsten et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice

(2014) Shawn Albers et al.   NEUROBIOLOGY OF DISEASE

APP Homodimers Transduce an Amyloid-β-Mediated Increase in Release Probability at Excitatory Synapses

(2014) Hilla Fogel et al.   Cell Reports

New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF

(2013) Ting Yang et al.   Alzheimers & Dementia

High apolipoprotein E in cerebrospinal fluid of patients with Lewy body disorders is associated with dementia

(2013) Swetha Vijayaraghavan et al.   Alzheimers & Dementia

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Hypercholesterolemia induces short-term spatial memory impairments in mice: up-regulation of acetylcholinesterase activity as an early and causal event?

(2013) Eduardo Luiz Gasnhar Moreira et al.   JOURNAL OF NEURAL TRANSMISSION

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

(2013) V K Ramanan et al.   MOLECULAR PSYCHIATRY

Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease

(2013) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

(2013) Swetha Vijayaraghavan et al.   PLoS One

Amyloid-beta oligomerization in Alzheimer dementia versus high-pathology controls

(2012) Thomas J. Esparza et al.   ANNALS OF NEUROLOGY

Inhibition of Choline Acetyltransferase as a Mechanism for Cholinergic Dysfunction Induced by Amyloid-β Peptide Oligomers

(2012) Nilson Nunes-Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Cholesterol Level and Statin Use in Alzheimer Disease

(2011) Nina E. Shepardson   ARCHIVES OF NEUROLOGY

Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo

(2010) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

The apolipoprotein E ε4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase

(2009) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE

Amyloid-cholinesterase interactions

(2008) Nibaldo C. Inestrosa et al.   FEBS Journal

Human Recombinant Butyrylcholinesterase Purified from the Milk of Transgenic Goats Interacts with Beta-Amyloid Fibrils and Suppresses Their Formation in vitro

(2008) E. Podoly et al.   Neurodegenerative Diseases

Vaccination with soluble Aβ oligomers generates toxicity-neutralizing antibodies

(2003) Mary P. Lambert et al.   JOURNAL OF NEUROCHEMISTRY