Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells

TGF-β in Epithelial to Mesenchymal Transition and Metastasis of Liver Carcinoma

(2012) Patrick Reichl et al.   CURRENT PHARMACEUTICAL DESIGN

Induction of epithelial–mesenchymal transition by transforming growth factor β

(2012) Aristidis Moustakas et al.   SEMINARS IN CANCER BIOLOGY

The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms

(2011) Laia Caja et al.   BIOCHEMICAL PHARMACOLOGY

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

CXCL12 (SDF1 )-CXCR4/CXCR7 Pathway Inhibition: An Emerging Sensitizer for Anticancer Therapies?

(2011) D. G. Duda et al.   CLINICAL CANCER RESEARCH

Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss

(2011) Shelli M. Morris et al.   HEPATOLOGY

Roles of Chemokine Receptor 4 (CXCR4) and Chemokine Ligand 12 (CXCL12) in Metastasis of Hepatocellular Carcinoma Cells

(2010) Hui Liu et al.   Cellular & Molecular Immunology

Snail1 suppresses TGF- -induced apoptosis and is sufficient to trigger EMT in hepatocytes

(2010) D. L. Franco et al.   JOURNAL OF CELL SCIENCE

Expression of the chemokine receptor CXCR4 in human hepatocellular carcinoma and its role in portal vein tumor thrombus

(2010) Nan Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Latent Bone Metastasis in Breast Cancer Tied to Src-Dependent Survival Signals

(2009) Xiang H.-F. Zhang et al.   CANCER CELL

Overactivation of the MEK/ERK Pathway in Liver Tumor Cells Confers Resistance to TGF- -Induced Cell Death through Impairing Up-regulation of the NADPH Oxidase NOX4

(2009) L. Caja et al.   CANCER RESEARCH

Role of CXCR4/SDF-1α in the migratory phenotype of hepatoma cells that have undergone epithelial–mesenchymal transition in response to the transforming growth factor-β

(2009) Esther Bertran et al.   CELLULAR SIGNALLING

Hypotheses on the Role of Transforming Growth Factor-β in the Onset and Progression of Hepatocellular Carcinoma

(2009) Steven Dooley et al.   DIGESTIVE DISEASES

Targeting transforming growth factor (TGF)-βRI inhibits activation of β1 integrin and blocks vascular invasion in hepatocellular carcinoma

(2009) Emilia Fransvea et al.   HEPATOLOGY

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-β signaling from tumor suppression to oncogenesis in early chronic hepatitis B

(2009) Miki Murata et al.   HEPATOLOGY

TGFβ in Cancer

(2008) Joan Massagué   CELL

The TGFß pathway as a therapeutic target in cancer

(2008) Joan Seoane   Clinical & Translational Oncology

Cytokine regulation networks in the cancer microenvironment

(2008) Bor-Ching Sheu   Frontiers in Bioscience-Landmark

Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis

(2008) Hye Jung Baek et al.   HEPATOLOGY

Transforming growth factor-β gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

(2008) Cédric Coulouarn et al.   HEPATOLOGY

Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

(2008) Emilia Fransvea et al.   HEPATOLOGY

New insights on the role of CXCR4 in cancer metastasis

(2008) A Zlotnik   JOURNAL OF PATHOLOGY