Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether
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Title
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether
Authors
Keywords
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Journal
eLife
Volume 8, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2019-05-31
DOI
10.7554/elife.46595
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- (2008) D. M. Schewe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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