Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics
Authors
Keywords
-
Journal
Toxins
Volume 11, Issue 6, Pages 355
Publisher
MDPI AG
Online
2019-06-19
DOI
10.3390/toxins11060355
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in Drosophila
- (2018) Mitsuko Katsukawa et al. CURRENT BIOLOGY
- Recombinant Protein Containing B-Cell Epitopes of Different Loxosceles Spider Toxins Generates Neutralizing Antibodies in Immunized Rabbits
- (2018) Sabrina de Almeida Lima et al. Frontiers in Immunology
- A New Anti-loxoscelic Serum Produced Against Recombinant Sphingomyelinase D: Results of Preclinical Trials
- (2018) Daniel Manzoni de Almeida et al. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
- The Opportunity of Precision Medicine for Breast Cancer With Context-Sensitive Tumor Suppressor Maspin
- (2017) Margarida M. Bernardo et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Serpins in arthropod biology
- (2017) David A. Meekins et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Phoneutria nigriventer spider toxin Tx2-6 induces priapism in mice even after cavernosal denervation
- (2017) Katherine Garcia Ravelli et al. TOXICON
- A multi-protease, multi-dissociation, bottom-up-to-top-down proteomic view of the Loxosceles intermedia venom
- (2017) Dilza Trevisan-Silva et al. Scientific Data
- Active site mapping of Loxosceles phospholipases D: Biochemical and biological features
- (2016) L. Vuitika et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Insecticidal activity of a recombinant knottin peptide fromLoxosceles intermediavenom and recognition of these peptides as a conserved family in the genus
- (2016) F. H. Matsubara et al. INSECT MOLECULAR BIOLOGY
- Potential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase-D
- (2016) Daniele Chaves-Moreira et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Venomous extract protein profile of Brazilian tarantula Grammostola iheringi : searching for potential biotechnological applications
- (2016) Marcia H. Borges et al. Journal of Proteomics
- Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach
- (2015) Julie K Klint et al. BRITISH JOURNAL OF PHARMACOLOGY
- Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D
- (2015) M.A. Coronado et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions
- (2015) Tae Kwon Kim et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- PnPP-19, a Synthetic and Nontoxic Peptide Designed from a Phoneutria nigriventer Toxin, Potentiates Erectile Function via NO/cGMP
- (2015) Carolina Nunes Silva et al. JOURNAL OF UROLOGY
- Translationally controlled tumor protein supplemented chitosan modified glass ionomer cement promotes osteoblast proliferation and function
- (2015) Jiraporn Sangsuwan et al. Materials Science & Engineering C-Materials for Biological Applications
- Anti-loxoscelic horse serum produced against a recombinant dermonecrotic protein of Brazilian Loxosceles intermedia spider neutralize lethal effects of Loxosceles laeta venom from Peru
- (2015) C.G. Duarte et al. TOXICON
- Brown spider (Loxosceles genus) venom toxins: Evaluation of biological conservation by immune cross-reactivity
- (2015) Daniela Regina Buch et al. TOXICON
- The Cystine Knot Is Responsible for the Exceptional Stability of the Insecticidal Spider Toxin ω-Hexatoxin-Hv1a
- (2015) Volker Herzig et al. Toxins
- Harnessing the anti-inflammatory potential of palmitoylethanolamide
- (2014) Mireille Alhouayek et al. DRUG DISCOVERY TODAY
- Immunization of mice withPlasmodiumTCTP delays establishment ofPlasmodiuminfection
- (2014) K. J. Taylor et al. PARASITE IMMUNOLOGY
- Correction: Discovery of a Distinct Superfamily of Kunitz-Type Toxin (KTT) from Tarantulas
- (2014) Chun-Hua Yuan et al. PLoS One
- Innovative immunization protocols using chimeric recombinant protein for the production of polyspecific loxoscelic antivenom in horses
- (2014) Luís F.M. Figueiredo et al. TOXICON
- Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins
- (2014) Luiza Helena Gremski et al. TOXICON
- Cloning, expression and characterization of a phospholipase D from Loxosceles gaucho venom gland
- (2013) Geraldo S. Magalhães et al. BIOCHIMIE
- Serpins, Immunity and Autoimmunity: Old Molecules, New Functions
- (2013) Mariele Gatto et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Amblyomma americanumtick saliva serine protease inhibitor 6 is a cross-class inhibitor of serine proteases and papain-like cysteine proteases that delays plasma clotting and inhibits platelet aggregation
- (2013) A. Mulenga et al. INSECT MOLECULAR BIOLOGY
- Brown spider phospholipase-D containing a conservative mutation (D233E) in the catalytic site: Identification and functional characterization
- (2013) Larissa Vuitika et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- On employing a translationally controlled tumor protein-derived protein transduction domain analog for transmucosal delivery of drugs
- (2013) Hae-duck Bae et al. JOURNAL OF CONTROLLED RELEASE
- Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features
- (2013) L. Zimmermann et al. JOURNAL OF NEUROSCIENCE
- Spit and Venom from Scytodes Spiders: A Diverse and Distinct Cocktail
- (2013) Pamela A. Zobel-Thropp et al. JOURNAL OF PROTEOME RESEARCH
- Phospholipase D Toxins of Brown Spider Venom Convert Lysophosphatidylcholine and Sphingomyelin to Cyclic Phosphates
- (2013) Daniel M. Lajoie et al. PLoS One
- Modulation of membrane phospholipids, the cytosolic calcium influx and cell proliferation following treatment of B16-F10 cells with recombinant phospholipase-D from Loxosceles intermedia (brown spider) venom
- (2013) Ana Carolina Martins Wille et al. TOXICON
- A novel ICK peptide from the Loxosceles intermedia (brown spider) venom gland: Cloning, heterologous expression and immunological cross-reactivity approaches
- (2013) Fernando Hitomi Matsubara et al. TOXICON
- Differential metalloprotease content and activity of three Loxosceles spider venoms revealed using two-dimensional electrophoresis approaches
- (2013) Dilza Trevisan-Silva et al. TOXICON
- New insights on arthropod toxins that potentiate erectile function
- (2013) Kenia P. Nunes et al. TOXICON
- Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels
- (2013) Anne Baron et al. TOXICON
- Generation and characterization of a recombinant chimeric protein (rCpLi) consisting of B-cell epitopes of a dermonecrotic protein from Loxosceles intermedia spider venom
- (2013) T.M. Mendes et al. VACCINE
- A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization
- (2013) Valéria Pereira Ferrer et al. PLoS Neglected Tropical Diseases
- Transduction of translationally controlled tumor protein employing TCTP-derived protein transduction domain
- (2012) Jeehye Maeng et al. ANALYTICAL BIOCHEMISTRY
- Sphingomyelinase D Activity in Model Membranes: Structural Effects of in situ Generation of Ceramide-1-Phosphate
- (2012) Roberto P. Stock et al. PLoS One
- Novel Scabies Mite Serpins Inhibit the Three Pathways of the Human Complement System
- (2012) Angela Mika et al. PLoS One
- Effects of C1 Inhibitor on Tissue Damage in a Porcine Model of Controlled Hemorrhage
- (2012) Jurandir J. Dalle Lucca et al. SHOCK
- A brief review of the scientific history of several lesser-known snake venom proteins: l-amino acid oxidases, hyaluronidases and phosphodiesterases
- (2012) Jay W. Fox TOXICON
- TPT1/ TCTP-regulated pathways in phenotypic reprogramming
- (2012) Robert Amson et al. TRENDS IN CELL BIOLOGY
- Spider-Venom Peptides as Bioinsecticides
- (2012) Monique J. Windley et al. Toxins
- Structure of a novel class II phospholipase D: Catalytic cleft is modified by a disulphide bridge
- (2011) Priscila Oliveira de Giuseppe et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phospholipase D: Enzymology, Functionality, and Chemical Modulation
- (2011) Paige E. Selvy et al. CHEMICAL REVIEWS
- Loxosceles gaucho spider venom and its sphingomyelinase fraction trigger the main functions of human and rabbit platelets
- (2011) Flávio L Tavares et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Molecular cloning, heterologous expression and functional characterization of a novel translationally-controlled tumor protein (TCTP) family member from Loxosceles intermedia (brown spider) venom
- (2011) Youssef B. Sade et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The relationship between calcium and the metabolism of plasma membrane phospholipids in hemolysis induced by brown spider venom phospholipase-D toxin
- (2011) Daniele Chaves-Moreira et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Histamine-releasing factor has a proinflammatory role in mouse models of asthma and allergy
- (2011) Jun-ichi Kashiwakura et al. JOURNAL OF CLINICAL INVESTIGATION
- Translationally controlled tumor protein against apoptosis from 2-hydroxy-ethyl methacrylate in human dental pulp cells
- (2011) Nattaporn Wanachottrakul et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- Serpin structure, function and dysfunction
- (2011) J. A. HUNTINGTON JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Evaluating antioxidative activities of amino acid substitutions on mastoparan-B
- (2011) Mars J. Yang et al. PEPTIDES
- Protection against the toxic effects of Loxosceles intermedia spider venom elicited by mimotope peptides
- (2011) J. de Moura et al. VACCINE
- Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes
- (2011) Olga Meiri Chaim et al. Toxins
- Phospholipase-D activity and inflammatory response induced by brown spider dermonecrotic toxin: Endothelial cell membrane phospholipids as targets for toxicity
- (2010) Olga M. Chaim et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation
- (2010) J. Chmelar et al. BLOOD
- A novel expression profile of the Loxosceles intermedia spider venomous gland revealed by transcriptome analysis
- (2010) Luiza Helena Gremski et al. Molecular BioSystems
- Inflammatory mediators generated at the site of inoculation of Loxosceles gaucho spider venom
- (2010) Katia C. Barbaro et al. TOXICON
- Spider-Venom Peptides as Therapeutics
- (2010) Natalie J. Saez et al. Toxins
- Astacin-like metalloproteases are a gene family of toxins present in the venom of different species of the brown spider (genus Loxosceles)
- (2009) Dilza Trevisan-Silva et al. BIOCHIMIE
- Ixodes scapularis tick serine proteinase inhibitor (serpin) gene family; annotation and transcriptional analysis
- (2009) Albert Mulenga et al. BMC GENOMICS
- Hyaluronidase Inhibitors: A Biological and Therapeutic Perspective
- (2009) K. Girish et al. CURRENT MEDICINAL CHEMISTRY
- Resveratrol attenuates C5a-induced inflammatory responses in vitro and in vivo by inhibiting phospholipase D and sphingosine kinase activities
- (2009) Priya D. A. Issuree et al. FASEB JOURNAL
- Identification of a direct hemolytic effect dependent on the catalytic activity induced by phospholipase-D (dermonecrotic toxin) from brown spider venom
- (2009) Daniele Chaves-Moreira et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Analysis of therapeutic benefits of antivenin at different time intervals after experimental envenomation in rabbits by venom of the brown spider (Loxosceles intermedia)
- (2009) Isolete Pauli et al. TOXICON
- A protective immune response against lethal, dermonecrotic and hemorrhagic effects of Loxosceles intermedia venom elicited by a 27-residue peptide
- (2009) C. Dias-Lopes et al. TOXICON
- Nephrotoxicity caused by brown spider venom phospholipase-D (dermonecrotic toxin) depends on catalytic activity
- (2008) J. Kusma et al. BIOCHIMIE
- Transcriptome analysis of Loxosceles laeta (Araneae, Sicariidae) spider venomous gland using expressed sequence tags
- (2008) Matheus de F Fernandes-Pedrosa et al. BMC GENOMICS
- The molecular aetiology of the serpinopathies
- (2008) M DAVIES et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Identification, cloning and functional characterization of a novel dermonecrotic toxin (phospholipase D) from brown spider (Loxosceles intermedia) venom
- (2007) Marcia Helena Appel et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Biotechnological applications of brown spider (Loxosceles genus) venom toxins
- (2007) Andrea Senff-Ribeiro et al. BIOTECHNOLOGY ADVANCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now