Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host

(2019) Guangxu Ma et al.   Parasites & Vectors

RNAi-mediated knockdown of daf-12 in the model parasitic nematode Strongyloides ratti

(2019) Alex Dulovic et al.   PLoS Pathogens

Somatic proteome of Haemonchus contortus

(2019) Tao Wang et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Dauer signalling pathway model for Haemonchus contortus

(2019) Guangxu Ma et al.   Parasites & Vectors

Molecular alterations during larval development of Haemonchus contortus in vitro are under tight post-transcriptional control

(2018) Guangxu Ma et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The developmental lipidome of Haemonchus contortus

(2018) Tao Wang et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response

(2018) Nicholas O. Burton et al.   Nature Communications

A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry

(2017) Stephen R Doyle et al.   Genome Biology and Evolution

Nuclear receptors: emerging drug targets for parasitic diseases

(2017) Zhu Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Small-molecule pheromones and hormones controlling nematode development

(2017) Rebecca A Butcher   Nature Chemical Biology

Nuclear option prevents hyperinfection in theStrongyloidesworm war

(2017) Richard John Martin   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methylprednisolone acetate induces, and Δ7-dafachronic acid suppresses,Strongyloides stercoralishyperinfection in NSG mice

(2017) John B. Patton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making sense of genomes of parasitic worms: Tackling bioinformatic challenges

(2016) Pasi K. Korhonen et al.   BIOTECHNOLOGY ADVANCES

Expanding the view on the evolution of the nematode dauer signalling pathways: refinement through gene gain and pathway co-option

(2016) Aude Gilabert et al.   BMC GENOMICS

BlastKOALA and GhostKOALA: KEGG Tools for Functional Characterization of Genome and Metagenome Sequences

(2016) Minoru Kanehisa et al.   JOURNAL OF MOLECULAR BIOLOGY

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

Diapause is associated with a change in the polarity of secretion of insulin-like peptides

(2016) Yohei Matsunaga et al.   Nature Communications

Regulation of Life Cycle Checkpoints and Developmental Activation of Infective Larvae in Strongyloides stercoralis by Dafachronic Acid

(2016) Mennatallah M. Y. Albarqi et al.   PLoS Pathogens

Low cost whole-organism screening of compounds for anthelmintic activity

(2015) Sarah Preston et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes

(2015) Zhu Wang et al.   PLoS Genetics

FuncTree: Functional Analysis and Visualization for Large-Scale Omics Data

(2015) Takeru Uchiyama et al.   PLoS One

Comparative Metabolomics Reveals Endogenous Ligands of DAF-12, a Nuclear Hormone Receptor, Regulating C. elegans Development and Lifespan

(2014) Parag Mahanti et al.   Cell Metabolism

The evolution of parasitism in Nematoda

(2014) MARK BLAXTER et al.   PARASITOLOGY

The dauer hypothesis and the evolution of parasitism: 20years on and still going strong

(2013) Matt Crook   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Impact of gastrointestinal parasitic nematodes of sheep, and the role of advanced molecular tools for exploring epidemiology and drug resistance - an Australian perspective

(2013) Florian Roeber et al.   Parasites & Vectors

The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery

(2013) Roz Laing et al.   GENOME BIOLOGY

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus

(2013) Erich M Schwarz et al.   GENOME BIOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Steroids as Central Regulators of Organismal Development and Lifespan

(2012) Siu Sylvia Lee et al.   PLOS BIOLOGY

Hormonal Signal Amplification Mediates Environmental Conditions during Development and Controls an Irreversible Commitment to Adulthood

(2012) Oren N. Schaedel et al.   PLOS BIOLOGY

RNAseq Analysis of the Parasitic Nematode Strongyloides stercoralis Reveals Divergent Regulation of Canonical Dauer Pathways

(2012) Jonathan D. Stoltzfus et al.   PLoS Neglected Tropical Diseases

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Structural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in Nematodes

(2011) Xiaoyong Zhi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans

(2011) Genna M Luciani et al.   Nature Chemical Biology

Activation of Nippostrongylus brasiliensis infective larvae is regulated by a pathway distinct from the hookworm Ancylostoma caninum

(2010) Stanley Ching-Cheng Huang et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Co-option of the hormone-signalling module dafachronic acid–DAF-12 in nematode evolution

(2010) Gilberto Bento et al.   NATURE

How did parasitic worms evolve?

(2009) Mark E. Viney   BIOESSAYS

Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes

(2009) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans

(2009) C. M. Hammell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Hormone Receptor Regulation of MicroRNAs Controls Developmental Progression

(2009) Axel Bethke et al.   SCIENCE

A Conserved Endocrine Mechanism Controls the Formation of Dauer and Infective Larvae in Nematodes

(2008) Akira Ogawa et al.   CURRENT BIOLOGY

C. elegans dauer formation and the molecular basis of plasticity

(2008) N. Fielenbach et al.   GENES & DEVELOPMENT

Prolactin evokes lactational transmission of larvae in mice infected with Toxocara canis

(2008) Zongfan Jin et al.   PARASITOLOGY INTERNATIONAL