A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I

Meiosis: the chromosomal foundation of reproduction

(2018) Ewelina Bolcun-Filas et al.   BIOLOGY OF REPRODUCTION

Regulated Crossing-Over Requires Inactivation of Yen1/GEN1 Resolvase during Meiotic Prophase I

(2018) Meret Arter et al.   DEVELOPMENTAL CELL

A SUMO-ubiquitin relay recruits proteasomes to chromosome axes to regulate meiotic recombination

(2017) H. B. D. Prasada Rao et al.   SCIENCE

The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans

(2017) Carol M. Manhart et al.   PLOS BIOLOGY

Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair

(2017) Corentin Claeys Bouuaert et al.   PLoS Genetics

mlh3 mutations in baker’s yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide

(2017) Najla Al-Sweel et al.   PLoS Genetics

Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation

(2016) Stephen Gray et al.   Annual Review of Genetics

Top3-Rmi1 DNA Single-Strand Decatenase Is Integral to the Formation and Resolution of Meiotic Recombination Intermediates

(2015) Hardeep Kaur et al.   MOLECULAR CELL

Pervasive and Essential Roles of the Top3-Rmi1 Decatenase Orchestrate Recombination and Facilitate Chromosome Segregation in Meiosis

(2015) Shangming Tang et al.   MOLECULAR CELL

Mlh1-Mlh3, a Meiotic Crossover and DNA Mismatch Repair Factor, Is a Msh2-Msh3-stimulated Endonuclease

(2014) Maria V. Rogacheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TheSaccharomyces cerevisiaeMlh1-Mlh3 Heterodimer Is an Endonuclease That Preferentially Binds to Holliday Junctions

(2014) Lepakshi Ranjha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites

(2014) J. Kim Holloway et al.   JOURNAL OF CELL BIOLOGY

Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination

(2014) Huanyu Qiao et al.   NATURE GENETICS

Mus81-Mms4 and Yen1 resolve a novel anaphase bridge formed by noncanonical Holliday junctions

(2014) Jonay García-Luis et al.   Nature Communications

RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis

(2013) April Reynolds et al.   NATURE GENETICS

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site

(2013) Emeric Gueneau et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conditional Inactivation of the DNA Damage Response Gene Hus1 in Mouse Testis Reveals Separable Roles for Components of the RAD9-RAD1-HUS1 Complex in Meiotic Chromosome Maintenance

(2013) Amy M. Lyndaker et al.   PLoS Genetics

Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs

(2013) Adam Auton et al.   PLoS Genetics

Delineation of Joint Molecule Resolution Pathways in Meiosis Identifies a Crossover-Specific Resolvase

(2012) Kseniya Zakharyevich et al.   CELL

Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange

(2012) S. Munoz-Galvan et al.   MOLECULAR AND CELLULAR BIOLOGY

BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

(2012) Arnaud De Muyt et al.   MOLECULAR CELL

Mammalian BTBD12 (SLX4) Protects against Genomic Instability during Mammalian Spermatogenesis

(2011) J. Kim Holloway et al.   PLoS Genetics

Recombination Proteins Mediate Meiotic Spatial Chromosome Organization and Pairing

(2010) Aurora Storlazzi et al.   CELL

Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination

(2010) J. Kim Holloway et al.   JOURNAL OF CELL BIOLOGY

Comprehensive, Fine-Scale Dissection of Homologous Recombination Outcomes at a Hot Spot in Mouse Meiosis

(2010) Francesca Cole et al.   MOLECULAR CELL

Genetic Analysis of Baker's Yeast Msh4-Msh5 Reveals a Threshold Crossover Level for Meiotic Viability

(2010) K. T. Nishant et al.   PLoS Genetics

MER3 is required for normal meiotic crossover formation, but not for presynaptic alignment in rice

(2009) K. Wang et al.   JOURNAL OF CELL SCIENCE

Distinct Functions of MLH3 at Recombination Hot Spots in the Mouse

(2008) A. Svetlanov et al.   GENETICS

A Mutation in the Putative MLH3 Endonuclease Domain Confers a Defect in Both Mismatch Repair and Meiosis in Saccharomyces cerevisiae

(2008) K. T. Nishant et al.   GENETICS

RecQ Helicase, Sgs1, and XPF Family Endonuclease, Mus81-Mms4, Resolve Aberrant Joint Molecules during Meiotic Recombination

(2008) Steve D. Oh et al.   MOLECULAR CELL

Mus81/Mms4 Endonuclease and Sgs1 Helicase Collaborate to Ensure Proper Recombination Intermediate Metabolism during Meiosis

(2008) Lea Jessop et al.   MOLECULAR CELL

Crossover assurance and crossover interference are distinctly regulated by the ZMM proteins during yeast meiosis

(2008) Miki Shinohara et al.   NATURE GENETICS

Expression and functional analysis of AtMUS81 in Arabidopsis meiosis reveals a role in the second pathway of crossing-over

(2008) James D. Higgins et al.   PLANT JOURNAL

MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis

(2008) J. Kim Holloway et al.   PLoS Genetics

Comparative Analysis of Meiotic Progression in Female Mice Bearing Mutations in Genes of the DNA Mismatch Repair Pathway1

(2007) Rui Kan et al.   BIOLOGY OF REPRODUCTION