Syntrophy emerges spontaneously in complex metabolic systems

Costless metabolic secretions as drivers of interspecies interactions in microbial ecosystems

(2019) Alan R. Pacheco et al.   Nature Communications

Metabolic model-based analysis of the emergence of bacterial cross-feeding via extensive gene loss

(2018) Colin P. McNally et al.   BMC Systems Biology

Ecology and evolution of metabolic cross-feeding interactions in bacteria

(2018) Glen D'Souza et al.   NATURAL PRODUCT REPORTS

Evolution of bidirectional costly mutualism from byproduct consumption

(2018) William R. Harcombe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmentally Mediated Social Dilemmas

(2018) Sylvie Estrela et al.   TRENDS IN ECOLOGY & EVOLUTION

Bacterial Unculturability and the Formation of Intercellular Metabolic Networks

(2017) Samay Pande et al.   TRENDS IN MICROBIOLOGY

Paradoxes in leaky microbial trade

(2017) Yoav Kallus et al.   Nature Communications

Genome-driven evolutionary game theory helps understand the rise of metabolic interdependencies in microbial communities

(2017) Ali R. Zomorrodi et al.   Nature Communications

The potential for non-adaptive origins of evolutionary innovations in central carbon metabolism

(2016) Sayed-Rzgar Hosseini et al.   BMC Systems Biology

An oligotrophic deep-subsurface community dependent on syntrophy is dominated by sulfur-driven autotrophic denitrifiers

(2016) Maggie C. Y. Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thousands of microbial genomes shed light on interconnected biogeochemical processes in an aquifer system

(2016) Karthik Anantharaman et al.   Nature Communications

Resource Availability Modulates the Cooperative and Competitive Nature of a Microbial Cross-Feeding Mutualism

(2016) Tim A. Hoek et al.   PLOS BIOLOGY

Experimental Evolution of Metabolic Dependency in Bacteria

(2016) Glen D’Souza et al.   PLoS Genetics

Private benefits and metabolic conflicts shape the emergence of microbial interdependencies

(2015) Sylvie Estrela et al.   ENVIRONMENTAL MICROBIOLOGY

Metabolic dependencies drive species co-occurrence in diverse microbial communities

(2015) Aleksej Zelezniak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Black Queen evolution: the role of leakiness in structuring microbial communities

(2015) J. Jeffrey Morris   TRENDS IN GENETICS

Nutritional stress induces exchange of cell material and energetic coupling between bacterial species

(2015) Saida Benomar et al.   Nature Communications

LESS IS MORE: SELECTIVE ADVANTAGES CAN EXPLAIN THE PREVALENT LOSS OF BIOSYNTHETIC GENES IN BACTERIA

(2014) Glen D'Souza et al.   EVOLUTION

Enzyme Promiscuity: Engine of Evolutionary Innovation

(2014) Chetanya Pandya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptive Evolution of Synthetic Cooperating Communities Improves Growth Performance

(2014) Xiaolin Zhang et al.   PLoS One

Erosion of functional independence early in the evolution of a microbial mutualism

(2014) K. L. Hillesland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary limits to cooperation in microbial communities

(2014) Nuno M. Oliveira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Niche engineering demonstrates a latent capacity for fungal-algal mutualism

(2014) E. F. Y. Hom et al.   SCIENCE

Metabolic Resource Allocation in Individual Microbes Determines Ecosystem Interactions and Spatial Dynamics

(2014) William R. Harcombe et al.   Cell Reports

Construction of bacteria–eukaryote synthetic mutualism

(2013) Isao Kubo et al.   BIOSYSTEMS

Fitness and stability of obligate cross-feeding interactions that emerge upon gene loss in bacteria

(2013) Samay Pande et al.   ISME Journal

A latent capacity for evolutionary innovation through exaptation in metabolic systems

(2013) Aditya Barve et al.   NATURE

Characterization and modelling of interspecies electron transfer mechanisms and microbial community dynamics of a syntrophic association

(2013) Harish Nagarajan et al.   Nature Communications

From Metabolism to Ecology: Cross-Feeding Interactions Shape the Balance between Polymicrobial Conflict and Mutualism

(2012) Sylvie Estrela et al.   AMERICAN NATURALIST

Competition, Not Cooperation, Dominates Interactions among Culturable Microbial Species

(2012) Kevin R. Foster et al.   CURRENT BIOLOGY

The central role of the host cell in symbiotic nitrogen metabolism

(2012) S. J. Macdonald et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Black Queen Hypothesis: Evolution of Dependencies through Adaptive Gene Loss

(2012) J. J. Morris et al.   mBio

Synthetic Escherichia coli consortia engineered for syntrophy demonstrate enhanced biomass productivity

(2011) Hans C. Bernstein et al.   JOURNAL OF BIOTECHNOLOGY

Cooperative Adaptation to Establishment of a Synthetic Bacterial Mutualism

(2011) Kazufumi Hosoda et al.   PLoS One

Metabolic Flexibility of Sulfate-Reducing Bacteria

(2011) Caroline M. Plugge et al.   Frontiers in Microbiology

Genomic Insights into Syntrophy: The Paradigm for Anaerobic Metabolic Cooperation

(2010) Jessica R. Sieber et al.   Annual Review of Microbiology

Genotype networks in metabolic reaction spaces

(2010) Areejit Samal et al.   BMC Systems Biology

Dynamics in the mixed microbial concourse

(2010) E. H. Wintermute et al.   GENES & DEVELOPMENT

Emergent cooperation in microbial metabolism

(2010) Edwin H Wintermute et al.   Molecular Systems Biology

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Rapid evolution of stability and productivity at the origin of a microbial mutualism

(2010) K. L. Hillesland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environments that Induce Synthetic Microbial Ecosystems

(2010) Niels Klitgord et al.   PLoS Computational Biology

Electron transfer in syntrophic communities of anaerobic bacteria and archaea

(2009) Alfons J. M. Stams et al.   NATURE REVIEWS MICROBIOLOGY

Physiology, Ecology, Phylogeny, and Genomics of Microorganisms Capable of Syntrophic Metabolism

(2008) Michael J. McInerney et al.   Annals of the New York Academy of Sciences