Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling
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Title
Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-31
DOI
10.1038/s41598-019-47539-0
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- (2018) Maiara de Souza Oliveira et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Sreekanth Thota et al. JOURNAL OF MEDICINAL CHEMISTRY
- 3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial
- (2018) Timothy J Iveson et al. LANCET ONCOLOGY
- Ru(ii)–thyminate complexes: new metallodrug candidates against tumor cells
- (2018) Rodrigo S. Correa et al. NEW JOURNAL OF CHEMISTRY
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- (2018) Nanashara C. de Carvalho et al. Cell Death & Disease
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- (2018) Valdenizia Rodrigues Silva et al. Scientific Reports
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
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- (2018) Vania Vidimar et al. CANCER LETTERS
- A novel platinum complex containing a piplartine derivative exhibits enhanced cytotoxicity, causes oxidative stress and triggers apoptotic cell death by ERK/p38 pathway in human acute promyelocytic leukemia HL-60 cells
- (2018) Maiara de S. Oliveira et al. Redox Biology
- A ruthenium(II) complex containing a p-cresol group induces apoptosis in human cervical carcinoma cells through endoplasmic reticulum stress and reactive oxygen species production
- (2018) Li Xu et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives
- (2017) Tatjana Lazarević et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling
- (2017) Simon J. Cook et al. FEBS Journal
- Cytotoxicity in vitro, cellular uptake, localization and apoptotic mechanism studies induced by ruthenium(II) complex
- (2017) Jincan Chen et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells
- (2017) Isabelle Corre et al. Oncotarget
- Thirty Years of the Drug Candidate NAMI-A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective
- (2016) Enzo Alessio EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
- Structural Determinants of p53-Independence in Anticancer Ruthenium-Arene Schiff-Base Complexes
- (2016) Mun Juinn Chow et al. MOLECULAR PHARMACEUTICS
- The role of p53 in cancer drug resistance and targeted chemotherapy
- (2016) Karin Hientz et al. Oncotarget
- Recent Therapeutic Advances in the Treatment of Colorectal Cancer
- (2015) Kristen K. Ciombor et al. Annual Review of Medicine
- Compromised MAPK signaling in human diseases: an update
- (2015) Eun Kyung Kim et al. ARCHIVES OF TOXICOLOGY
- Anti-cancer drug KP1019 modulates epigenetics and induces DNA damage response inSaccharomyces cerevisiae
- (2014) Vikash Singh et al. FEBS LETTERS
- Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
- (2014) Suzanne Leijen et al. INVESTIGATIONAL NEW DRUGS
- Metal-based antitumour drugs in the post-genomic era: what comes next?
- (2011) Gianni Sava et al. DALTON TRANSACTIONS
- Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation
- (2010) Fengxiang Wei et al. CELLULAR SIGNALLING
- Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase I dose-escalation study
- (2009) Frederike Lentz et al. ANTI-CANCER DRUGS
- The ruthenium(II)–arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53–JNK pathways
- (2008) Soumya Chatterjee et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
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