Influence of SHH/GLI1 axis on EMT mediated migration and invasion of breast cancer cells

Involvement of hedgehog pathway in early onset, aggressive molecular subtypes and metastatic potential of breast cancer

(2018) Syeda Kiran Riaz et al.   Cell Communication and Signaling

Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer

(2018) Sherona R. Sirkisoon et al.   ONCOGENE

The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells

(2017) Jing-Bo Shao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cancer statistics, 2016

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Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells

(2016) F Faião-Flores et al.   ONCOGENE

In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors

(2016) Monica Benvenuto et al.   Oncotarget

Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors

(2016) Tadas Rimkus et al.   Cancers

The ImageJ ecosystem: An open platform for biomedical image analysis

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Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients

(2015) J Liu et al.   ONCOGENE

p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling

(2015) Elisa Maria Memmi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sonic hedgehog–Gli1 signals promote epithelial–mesenchymal transition in ovarian cancer by mediating PI3K/AKT pathway

(2014) Zhang Ke et al.   MEDICAL ONCOLOGY

Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression

(2014) Hai-Xia Fan et al.   MEDICAL ONCOLOGY

Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation

(2014) Ying Sun et al.   Molecular Cancer

Sonic Hedgehog-Gli1 Signaling Pathway Regulates the Epithelial Mesenchymal Transition (EMT) by Mediating a New Target Gene, S100A4, in Pancreatic Cancer Cells

(2014) Xuanfu Xu et al.   PLoS One

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutations in the Hedgehog Pathway Genes SMO and PTCH1 in Human Gastric Tumors

(2013) Xi-De Wang et al.   PLoS One

GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft

(2012) Junsheng Fu et al.   CANCER LETTERS

Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer

(2011) S. A. O'Toole et al.   CANCER RESEARCH

Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells

(2011) X Cao et al.   ONCOGENE

A Novel Splice Variant of GLI1 That Promotes Glioblastoma Cell Migration and Invasion

(2009) H.-W. Lo et al.   CANCER RESEARCH

The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts

(2009) A Shaw et al.   ONCOGENE

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE

Reciprocal Intraepithelial Interactions Between TP63 and Hedgehog Signaling Regulate Quiescence and Activation of Progenitor Elaboration by Mammary Stem Cells

(2008) Na Li et al.   STEM CELLS