Sonic Hedgehog-Gli1 Signaling Pathway Regulates the Epithelial Mesenchymal Transition (EMT) by Mediating a New Target Gene, S100A4, in Pancreatic Cancer Cells

SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial–mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway

(2012) Xuqi Li et al.   CANCER LETTERS

Building the niche: The role of the S100 proteins in metastatic growth

(2012) Eugene Lukanidin et al.   SEMINARS IN CANCER BIOLOGY

Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer

(2011) D. Ansari et al.   BRITISH JOURNAL OF SURGERY

S100A4 calcium-binding protein is key player in tumor progression and metastasis: preclinical and clinical evidence

(2011) Shrawan Kumar Mishra et al.   CANCER AND METASTASIS REVIEWS

Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer

(2011) Hideya Onishi et al.   CANCER SCIENCE

Update on the epidermal differentiation complex

(2011) Julie Henry   Frontiers in Bioscience-Landmark

Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics

(2011) Su-Ni Tang et al.   INTERNATIONAL JOURNAL OF CANCER

S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI Imaging

(2011) Martin Nipp et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity

(2011) Hong-Yan Zhang et al.   MOLECULAR BIOLOGY REPORTS

Pancreatic cancer: Overview of descriptive epidemiology

(2011) Cristina Bosetti et al.   MOLECULAR CARCINOGENESIS

Molecular Pathogenesis of Pancreatic Cancer and Clinical Perspectives

(2011) D. Matthaios et al.   ONCOLOGY

DeltaNp63alpha-Mediated Induction of Epidermal Growth Factor Receptor Promotes Pancreatic Cancer Cell Growth and Chemoresistance

(2011) Alexey V. Danilov et al.   PLoS One

Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms

(2011) Brahma N. Singh et al.   PLoS One

Overexpression of S100A4 in human cancer cell lines resistant to methotrexate

(2010) Nuria Mencía et al.   BMC CANCER

Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor

(2010) K. Seidel et al.   DEVELOPMENT

Surgical Treatment of Pancreatic Cancer

(2009) Martin Loos et al.   Annals of the New York Academy of Sciences

Expression of the costimulatory molecule B7-H3 is associated with prolonged survival in human pancreatic cancer

(2009) Martin Loos et al.   BMC CANCER

Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation

(2009) Y. Katoh et al.   CURRENT MOLECULAR MEDICINE

S100A4 mRNA is a Diagnostic and Prognostic Marker in Pancreatic Carcinoma

(2009) Naoki Ikenaga et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer

(2009) J M Bailey et al.   ONCOGENE

14-3-3  Modulates Pancreatic Cancer Cell Survival and Invasiveness

(2008) D. Neupane et al.   CLINICAL CANCER RESEARCH

Sonic Hedgehog-responsive Genes in the Fetal Prostate

(2008) Min Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer

(2008) G. Feldmann et al.   MOLECULAR CANCER THERAPEUTICS

The Expression Pattern of PDX-1, SHH, Patched and Gli-1 Is Associated with Pathological and Clinical Features in Human Pancreatic Cancer

(2008) Karl Quint et al.   PANCREATOLOGY