Additive effects of inhibiting both mTOR and glutamine metabolism on the arthritis in SKG mice

mTOR inhibitor rapamycin induce polymorphonuclear myeloid-derived suppressor cells mobilization and function in protecting against acute graft-versus-host disease after bone marrow transplantation

(2018) Yu Lin et al.   CLINICAL IMMUNOLOGY

Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells

(2018) Michihito Kono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTORC1 and mTORC2 as regulators of cell metabolism in immunity

(2017) Monika Linke et al.   FEBS LETTERS

The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury

(2017) Chao Zhang et al.   Cell Death & Disease

Amino-acid transporters in T-cell activation and differentiation

(2017) Wenkai Ren et al.   Cell Death & Disease

Feasibility and antitumor efficacy in vivo, of simultaneously targeting glycolysis, glutaminolysis and fatty acid synthesis using lonidamine, 6-diazo-5-oxo-L-norleucine and orlistat in colon cancer

(2017) Diana Cervantes-Madrid et al.   Oncology Letters

CD11b+Gr-1dim Tolerogenic Dendritic Cell-Like Cells Are Expanded in Interstitial Lung Disease in SKG Mice

(2017) Sho Sendo et al.   Arthritis & Rheumatology

Metabolism Controls the Balance of Th17/T-Regulatory Cells

(2017) Licheng Sun et al.   Frontiers in Immunology

3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation

(2017) Takaichi Okano et al.   Scientific Reports

The potential therapeutic role of myeloid-derived suppressor cells in autoimmune arthritis

(2016) Yungang Wang et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function

(2016) Nyamdelger Sukhbaatar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Myeloid-Derived Suppressor Cells Are Controlled by Regulatory T Cells via TGF-β during Murine Colitis

(2016) Cho-Rong Lee et al.   Cell Reports

mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors

(2016) Tingting Wu et al.   Scientific Reports

Rapamycin Prolongs Cardiac Allograft Survival in a Mouse Model by Inducing Myeloid-Derived Suppressor Cells

(2015) T. Nakamura et al.   AMERICAN JOURNAL OF TRANSPLANTATION

mTORC1 signaling and IL-17 expression: Defining pathways and possible therapeutic targets

(2015) Wenkai Ren et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment

(2015) Kazuhiro Tanaka et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloid-derived suppressor cells regulate T cell and B cell responses during autoimmune disease

(2015) Kristen R. Crook et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Glutaminolysis as a target for cancer therapy

(2015) L Jin et al.   ONCOGENE

Control of macrophage metabolism and activation by mTOR and Akt signaling

(2015) Anthony J. Covarrubias et al.   SEMINARS IN IMMUNOLOGY

Effects of Adoptive Transferring Different Sources of Myeloid-Derived Suppressor Cells in Mice Corneal Transplant Survival

(2015) Yan He et al.   TRANSPLANTATION

Preventing Allograft Rejection by Targeting Immune Metabolism

(2015) Chen-Fang Lee et al.   Cell Reports

Reviving Lonidamine and 6-Diazo-5-oxo-L-norleucine to Be Used in Combination for Metabolic Cancer Therapy

(2015) Diana Cervantes-Madrid et al.   Biomed Research International

Tofacitinib Facilitates the Expansion of Myeloid-Derived Suppressor Cells and Ameliorates Arthritis in SKG Mice

(2015) Keisuke Nishimura et al.   Arthritis & Rheumatology

Functional characterization of myeloid-derived suppressor cell subpopulations during the development of experimental arthritis

(2014) Wenhong Wang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation

(2014) Mako Nakaya et al.   IMMUNITY

Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice

(2013) Yimin Fang et al.   Cell Metabolism

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

Myeloid-Derived Suppressor Cells Play Crucial Roles in the Regulation of Mouse Collagen-Induced Arthritis

(2013) W. Fujii et al.   JOURNAL OF IMMUNOLOGY

LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells

(2013) K. Hayashi et al.   JOURNAL OF IMMUNOLOGY

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

(2013) Linda V Sinclair et al.   NATURE IMMUNOLOGY

Regulation of Immune Responses by mTOR

(2012) Jonathan D. Powell et al.   Annual Review of Immunology

Suppression of dendritic cell maturation and T cell proliferation by synovial fluid myeloid cells from mice with autoimmune arthritis

(2012) Colt Egelston et al.   ARTHRITIS AND RHEUMATISM

Crucial Role of Granulocytic Myeloid-Derived Suppressor Cells in the Regulation of Central Nervous System Autoimmune Disease

(2011) M. Ioannou et al.   JOURNAL OF IMMUNOLOGY

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice

(2011) Kenta Misaki et al.   ARTHRITIS RESEARCH & THERAPY

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

(2009) Greg M. Delgoffe et al.   IMMUNITY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+cells

(2008) Sokol Haxhinasto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

(2008) S. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA