Acutely elevated O-GlcNAcylation suppresses hippocampal activity by modulating both intrinsic and synaptic excitability factors
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Title
Acutely elevated O-GlcNAcylation suppresses hippocampal activity by modulating both intrinsic and synaptic excitability factors
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-05-14
DOI
10.1038/s41598-019-43017-9
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Note: Only part of the references are listed.- Pharmacological Inhibition of O-GlcNAcase Enhances Autophagy in Brain through an mTOR-Independent Pathway
- (2018) Yanping Zhu et al. ACS Chemical Neuroscience
- Functional significance of O-GlcNAc modification in regulating neuronal properties
- (2018) Hongik Hwang et al. PHARMACOLOGICAL RESEARCH
- Mutations inN-acetylglucosamine (O-GlcNAc) transferase in patients with X-linked intellectual disability
- (2017) Anke P. Willems et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and characterization of a missense mutation in theO-linked β-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability
- (2017) Krithika Vaidyanathan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acute Increases in Protein O-GlcNAcylation Dampen Epileptiform Activity in Hippocampus
- (2017) Luke T. Stewart et al. JOURNAL OF NEUROSCIENCE
- Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease
- (2017) Sheng Wang et al. JOURNAL OF PATHOLOGY
- Protein O-GlcNAcylation: emerging mechanisms and functions
- (2017) Xiaoyong Yang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Role of Stress-Induced O-GlcNAc Protein Modification in the Regulation of Membrane Transport
- (2017) Viktória Fisi et al. Oxidative Medicine and Cellular Longevity
- Insights into the role of maladaptive hexosamine biosynthesis and O-GlcNAcylation in development of diabetic cardiac complications
- (2017) Cheng Xue Qin et al. PHARMACOLOGICAL RESEARCH
- O-GlcNAc transferase regulates excitatory synapse maturity
- (2017) Olof Lagerlöf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quantitative time-resolved chemoproteomics reveals that stableO-GlcNAc regulates box C/D snoRNP biogenesis
- (2017) Wei Qin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation
- (2017) Aneika C. Leney et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation
- (2017) Yong Ryoul Yang et al. Scientific Reports
- Weaker Functional Connectivity Strength in Patients with Type 2 Diabetes Mellitus
- (2017) Linlin Liu et al. Frontiers in Neuroscience
- The Biochemistry of O-GlcNAc Transferase: Which Functions Make It Essential in Mammalian Cells?
- (2016) Zebulon G. Levine et al. Annual Review of Biochemistry
- Nutrient regulation of gene expression by O-GlcNAcylation of chromatin
- (2016) Stéphan Hardivillé et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Loss ofO-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration
- (2016) Andrew C. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP−/− Mice
- (2016) Jing Fan et al. Frontiers in Cellular Neuroscience
- A Small Molecule That Inhibits OGT Activity in Cells
- (2015) Rodrigo F. Ortiz-Meoz et al. ACS Chemical Biology
- O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease
- (2015) Nicholas P. Marotta et al. Nature Chemistry
- Detection and identification ofO-GlcNAcylated proteins by proteomic approaches
- (2015) Anne-Sophie Vercoutter-Edouart et al. PROTEOMICS
- Giant ankyrin-G: A critical innovation in vertebrate evolution of fast and integrated neuronal signaling
- (2015) Paul M. Jenkins et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glucose Regulates Mitochondrial Motility via Milton Modification by O-GlcNAc Transferase
- (2014) Gulcin Pekkurnaz et al. CELL
- O-GlcNAc Transferase Enables AgRP Neurons to Suppress Browning of White Fat
- (2014) Hai-Bin Ruan et al. CELL
- Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation
- (2014) Stéphan Hardivillé et al. Cell Metabolism
- O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond
- (2014) Scott A. Yuzwa et al. CHEMICAL SOCIETY REVIEWS
- The Emerging Link betweenO-GlcNAc and Alzheimer Disease
- (2014) Yanping Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- O-GlcNAcylation of AMPA Receptor GluA2 Is Associated with a Novel Form of Long-Term Depression at Hippocampal Synapses
- (2014) E. W. Taylor et al. JOURNAL OF NEUROSCIENCE
- O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation
- (2014) Bin Guo et al. NATURE CELL BIOLOGY
- Sweet memories: 20 years of progress in research on cognitive functioning in diabetes
- (2013) Geert Jan Biessels EUROPEAN JOURNAL OF PHARMACOLOGY
- O-Linked β-N-Acetylglucosamine (O-GlcNAc) Site Thr-87 Regulates Synapsin I Localization to Synapses and Size of the Reserve Pool of Synaptic Vesicles
- (2013) Yuliya Skorobogatko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
- (2013) Jeffrey R. Erickson et al. NATURE
- O-GlcNAcase is essential for embryonic development and maintenance of genomic stability
- (2012) Yong Ryoul Yang et al. AGING CELL
- Role of HCN Channels in Neuronal Hyperexcitability after Subarachnoid Hemorrhage in Rats
- (2012) B. Li et al. JOURNAL OF NEUROSCIENCE
- Global Identification and Characterization of BothO-GlcNAcylation and Phosphorylation at the Murine Synapse
- (2012) Jonathan C. Trinidad et al. MOLECULAR & CELLULAR PROTEOMICS
- Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation
- (2012) Jessica E Rexach et al. Nature Chemical Biology
- Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
- (2012) Scott A Yuzwa et al. Nature Chemical Biology
- Developmental Regulation of Protein O-GlcNAcylation, O-GlcNAc Transferase, and O-GlcNAcase in Mammalian Brain
- (2012) Ying Liu et al. PLoS One
- Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability
- (2011) N. Ikematsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Downregulation of Dendritic HCN Channel Gating in Epilepsy Is Mediated by Altered Phosphorylation Signaling
- (2010) S. Jung et al. JOURNAL OF NEUROSCIENCE
- SYMPOSIUM REVIEW: Going native: voltage-gated potassium channels controlling neuronal excitability
- (2010) Jamie Johnston et al. JOURNAL OF PHYSIOLOGY-LONDON
- The axon initial segment and the maintenance of neuronal polarity
- (2010) Matthew N. Rasband NATURE REVIEWS NEUROSCIENCE
- Regulation of AMPA Receptor Trafficking by O-Glycosylation
- (2010) Takeshi Kanno et al. NEUROCHEMICAL RESEARCH
- Electrophysiological Effects of SKF83959 on Hippocampal CA1 Pyramidal Neurons: Potential Mechanisms for the Drug's Neuroprotective Effects
- (2010) Hong-Yuan Chu et al. PLoS One
- The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine
- (2009) John A. Hanover et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Loss of Dendritic HCN1 Subunits Enhances Cortical Excitability and Epileptogenesis
- (2009) Z. Huang et al. JOURNAL OF NEUROSCIENCE
- Subunit Composition of Synaptic AMPA Receptors Revealed by a Single-Cell Genetic Approach
- (2009) Wei Lu et al. NEURON
- Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides
- (2009) R. J. Chalkley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In VivoModulation ofO-GlcNAc Levels Regulates Hippocampal Synaptic Plasticity through Interplay with Phosphorylation
- (2008) Melanie K. Tallent et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
- (2008) Scott A Yuzwa et al. Nature Chemical Biology
- Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons
- (2008) Alexis M Stranahan et al. NATURE NEUROSCIENCE
- Cross-talk between GlcNAcylation and phosphorylation: Site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc
- (2008) Z. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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