Identification and characterization of a missense mutation in theO-linked β-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability

How the glycosyltransferase OGT catalyzes amide bond cleavage

(2016) John Janetzko et al.   Nature Chemical Biology

The Early MetazoanTrichoplax adhaerensPossesses a FunctionalO-GlcNAc System

(2015) Nithya Selvan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Affected Kindred Analysis of Human X Chromosome Exomes to Identify Novel X-Linked Intellectual Disability Genes

(2015) Tejasvi S. Niranjan et al.   PLoS One

O-GlcNAc transferase and O-GlcNAcase: achieving target substrate specificity

(2014) Alexis K. Nagel et al.   AMINO ACIDS

Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation

(2014) Stéphan Hardivillé et al.   Cell Metabolism

Functional O-GlcNAc modifications: Implications in molecular regulation and pathophysiology

(2014) Krithika Vaidyanathan et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hyper-O-GlcNAcylation Is Anti-apoptotic and Maintains Constitutive NF-κB Activity in Pancreatic Cancer Cells

(2013) Zhiyuan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development

(2013) C. L. Howerton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase

(2013) M. B. Lazarus et al.   SCIENCE

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

(2013) F. V. Rao et al.   Open Biology

O-GlcNAcase is essential for embryonic development and maintenance of genomic stability

(2012) Yong Ryoul Yang et al.   AGING CELL

Fragile X and X-Linked Intellectual Disability: Four Decades of Discovery

(2012) Herbert A. Lubs et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation

(2012) Scott A Yuzwa et al.   Nature Chemical Biology

Phosphorylation regulates human OCT4

(2012) J. Brumbaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-GlcNAc Transferase Catalyzes Site-Specific Proteolysis of HCF-1

(2011) Francesca Capotosti et al.   CELL

Epigenetic Regulation of Polymerase II Transcription Initiation in Trypanosoma cruzi: Modulation of Nucleosome Abundance, Histone Modification, and Polymerase Occupancy by O-Linked Thymine DNA Glucosylation

(2011) Dilrukshi Ekanayake et al.   EUKARYOTIC CELL

Genetics of Early Onset Cognitive Impairment

(2010) Hans Hilger Ropers   Annual Review of Genomics and Human Genetics

Modulation of transcription factor function by O-GlcNAc modification

(2010) Sabire Özcan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Versatile TPR domains accommodate different modes of target protein recognition and function

(2010) Rudi Kenneth Allan et al.   CELL STRESS & CHAPERONES

The prevalence of mental retardation: a critical review of recent literature

(2010) Nel Roeleveld et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

The genetic basis of non-syndromic intellectual disability: a review

(2010) Liana Kaufman et al.   Journal of Neurodevelopmental Disorders

Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia

(2010) Y Shi et al.   LEUKEMIA

Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc

(2010) Chin Fen Teo et al.   Nature Chemical Biology

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways

(2009) Q. Zeidan et al.   JOURNAL OF CELL SCIENCE

Utility of lymphoblastoid cell lines

(2009) L. Sie et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

O-Linked β-N-Acetylglucosaminyltransferase Substrate Specificity Is Regulated by Myosin Phosphatase Targeting and Other Interacting Proteins

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE