Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis
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Title
Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-05
DOI
10.1038/s41467-019-10839-0
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Note: Only part of the references are listed.- Antidiabetic drugs and stroke risk. Current evidence
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- (2017) Suet Ching Chen et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Comparative risk of serious hypoglycemia with oral antidiabetic monotherapy: A retrospective cohort study
- (2017) Charles E. Leonard et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Progress in the application and mechanism of metformin in treating non-small cell lung cancer
- (2017) Chan Li et al. Oncology Letters
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- (2017) Feng Yan et al. BMC Pulmonary Medicine
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- (2017) T Yu et al. Oncogenesis
- Matrix Remodeling in Pulmonary Fibrosis and Emphysema
- (2016) Tejaswini Kulkarni et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis
- (2016) Ting Xie et al. JOURNAL OF CLINICAL INVESTIGATION
- Correction: Kinomic Profiling of Electromagnetic Navigational Bronchoscopy Specimens: A New Approach for Personalized Medicine
- (2016) Joshua C. Anderson et al. PLoS One
- Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis
- (2015) Rafael Kramann et al. Cell Stem Cell
- Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures
- (2015) Franziska E. Uhl et al. EUROPEAN RESPIRATORY JOURNAL
- Idiopathic pulmonary fibrosis: Diagnosis, epidemiology and natural history
- (2015) Giacomo Sgalla et al. RESPIROLOGY
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- (2015) Joshua C. Anderson et al. PLoS One
- Peroxisomes: A Nexus for Lipid Metabolism and Cellular Signaling
- (2014) Irfan J. Lodhi et al. Cell Metabolism
- Rosiglitazone Dampens Pulmonary Inflammation in a Porcine Model of Acute Lung Injury
- (2014) Valbona Mirakaj et al. INFLAMMATION
- Upregulation of Heparan Sulfate 6-O-Sulfation in Idiopathic Pulmonary Fibrosis
- (2013) Jingning Lu et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
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- (2013) Hongli Sun et al. STEM CELLS
- Thy-1 Signals through PPARγ to Promote Lipofibroblast Differentiation in the Developing Lung
- (2012) Brian M. Varisco et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Fatty acids revert the inhibition of respiration caused by the antidiabetic drug metformin to facilitate their mitochondrial β-oxidation
- (2012) M. Mar González-Barroso et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- PPARγSignaling Mediates the Evolution, Development, Homeostasis, and Repair of the Lung
- (2012) Virender K. Rehan et al. PPAR Research
- MEK-ERK Pathway Modulation Ameliorates Pulmonary Fibrosis Associated with Epidermal Growth Factor Receptor Activation
- (2011) Satish K. Madala et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Cellular and molecular mechanisms of metformin: an overview
- (2011) Benoit Viollet et al. CLINICAL SCIENCE
- Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
- (2011) J. R. Rock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Peptide arrays for kinome analysis: New opportunities and remaining challenges
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- (2011) Esther Phielix et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Strategies for kinome profiling in cancer and potential clinical applications: chemical proteomics and array-based methods
- (2010) Sander R. Piersma et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- PPARγ in adipocyte differentiation and metabolism - Novel insights from genome-wide studies
- (2010) Rasmus Siersbaek et al. FEBS LETTERS
- Rosiglitazone prevents the progression of preinvasive lung cancer in a murine model
- (2009) C. M. Lyon et al. CARCINOGENESIS
- Deletion of PPAR in Alveolar Macrophages Is Associated with a Th-1 Pulmonary Inflammatory Response
- (2009) A. Malur et al. JOURNAL OF IMMUNOLOGY
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
- (2009) Linda Madisen et al. NATURE NEUROSCIENCE
- Risk factors for idiopathic pulmonary fibrosis in a Mexican population. A case-control study
- (2009) Ma. Cecilia García-Sancho Figueroa et al. RESPIRATORY MEDICINE
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- (2008) Olivia Wendling et al. GENESIS
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- (2008) Georg Hansmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation
- (2008) Tetsuya Hosooka et al. NATURE MEDICINE
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