Osteoblast-Targeted suppression of PPARγ increases osteogenesis through activation of mTOR signaling

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

(2012) Lingling Xian et al.   NATURE MEDICINE

PPARγ suppression inhibits adipogenesis but does not promote osteogenesis of human mesenchymal stem cells

(2011) Wei-Hua Yu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Osteoblast-targeted overexpression of PPARγ inhibited bone mass gain in male mice and accelerated ovariectomy-induced bone loss in female mice

(2011) Sun Wook Cho et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Erythropoietin mediated bone formation is regulated by mTOR signaling

(2011) Jinkoo Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

mTor Plays an Important Role in Odontoblast Differentiation

(2011) Jin-Koo Kim et al.   JOURNAL OF ENDODONTICS

mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS

(2010) H. R. Turnquist et al.   BLOOD

mTOR-Mediated Activation of p70 S6K Induces Differentiation of Pluripotent Human Embryonic Stem Cells

(2010) Charles A. Easley et al.   Cellular Reprogramming

Thiazolidinediones and fracture risk in patients with Type 2 diabetes

(2010) D. J. Betteridge   DIABETIC MEDICINE

Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice

(2010) Ganesh V. Halade et al.   EXPERIMENTAL GERONTOLOGY

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Adipocytes decrease Runx2 expression in osteoblastic cells: Roles of PPARγ and adiponectin

(2010) Li-Fen Liu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Leptin Functions Peripherally to Regulate Differentiation of Mesenchymal Progenitor Cells

(2010) Erica L. Scheller et al.   STEM CELLS

PPARγ in bone homeostasis

(2010) Yihong Wan   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein–protein interactions for substrate recognition

(2009) Elaine A. Dunlop et al.   CELLULAR SIGNALLING

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

PPARγ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells

(2009) Keith R. Shockley et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

(2009) Olaia Naveiras et al.   NATURE

Fat targets for skeletal health

(2009) Masanobu Kawai et al.   Nature Reviews Rheumatology

Fat and Beyond: The Diverse Biology of PPARγ

(2008) Peter Tontonoz et al.   Annual Review of Biochemistry

A Hierarchical Network Controls Protein Translation during Murine Embryonic Stem Cell Self-Renewal and Differentiation

(2008) Prabha Sampath et al.   Cell Stem Cell

Regulation of Osteoblast Differentiation by Slit2 in Osteoblastic Cells

(2008) Hongli Sun et al.   CELLS TISSUES ORGANS

Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells

(2007) Ujjal K. Singha et al.   JOURNAL OF CELLULAR BIOCHEMISTRY