Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks

PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation

(2018) Seung-Won Choi et al.   MOLECULAR CELL

The control of DNA repair by the cell cycle

(2017) Nicole Hustedt et al.   NATURE CELL BIOLOGY

New factors in mammalian DNA repair—the chromatin connection

(2017) G Raschellà et al.   ONCOGENE

Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

(2016) Petra Schwertman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA End Resection: Facts and Mechanisms

(2016) Ting Liu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Chromatin modification and NBS1: their relationship in DNA double-strand break repair

(2015) Yuichiro Saito et al.   GENES & GENETIC SYSTEMS

Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity

(2015) Fiachra Humphries et al.   IMMUNOLOGICAL REVIEWS

RNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break Repair

(2015) Akihiro Kato et al.   Genes

The MRE11 complex: An important source of stress relief

(2014) Katrin Rein et al.   EXPERIMENTAL CELL RESEARCH

Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination

(2014) Hye-Young Park et al.   JOURNAL OF CLINICAL INVESTIGATION

A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment

(2013) Anja M. Duursma et al.   MOLECULAR CELL

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

The RING Finger Protein RNF8 Ubiquitinates Nbs1 to Promote DNA Double-strand Break Repair by Homologous Recombination

(2012) Chi-Sheng Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skp2 E3 Ligase Integrates ATM Activation and Homologous Recombination Repair by Ubiquitinating NBS1

(2012) Juan Wu et al.   MOLECULAR CELL

Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks

(2012) Stephanie Panier et al.   MOLECULAR CELL

Regulation of DNA-End Resection by hnRNPU-like Proteins Promotes DNA Double-Strand Break Signaling and Repair

(2012) Sophie E. Polo et al.   MOLECULAR CELL

Transcriptional phenotypes of asthma defined by gene expression profiling of induced sputum samples

(2011) Katherine J. Baines et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

DNA-damage response and repair activities at uncapped telomeres depend on RNF8

(2011) Marieke H. Peuscher et al.   NATURE CELL BIOLOGY

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

(2011) Mikyoung Chang et al.   NATURE IMMUNOLOGY

The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection

(2011) Rekha Rai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

Mechanisms and regulation of DNA end resection

(2010) Maria Pia Longhese et al.   EMBO JOURNAL

RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX

(2009) Sabrina Pinato et al.   BMC MOLECULAR BIOLOGY

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Taking the time to make important decisions: The checkpoint effector kinases Chk1 and Chk2 and the DNA damage response

(2009) Travis H. Stracker et al.   DNA REPAIR

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites

(2009) Sairei So et al.   JOURNAL OF CELL BIOLOGY

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

Ubiquitylation in innate and adaptive immunity

(2009) Vijay G. Bhoj et al.   NATURE

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

(2008) J Ross Chapman et al.   EMBO REPORTS

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin

(2008) Fredrik Melander et al.   JOURNAL OF CELL BIOLOGY

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

(2008) L. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1

(2008) Chun-Chi Lin et al.   STRUCTURE