Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy

Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance

(2018) Nathan D. Hicks et al.   Nature Microbiology

ORBIT: a New Paradigm for Genetic Engineering of Mycobacterial Chromosomes

(2018) Kenan C. Murphy et al.   mBio

Esx Systems and the Mycobacterial Cell Envelope: What's the Connection?

(2017) Rachel E. Bosserman et al.   JOURNAL OF BACTERIOLOGY

Immune activation of the host cell induces drug tolerance inMycobacterium tuberculosisboth in vitro and in vivo

(2016) Yancheng Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

(2016) Marc Hafner et al.   NATURE METHODS

Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees

(2016) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

High Persister Mutants in Mycobacterium tuberculosis

(2016) Heather L. Torrey et al.   PLoS One

Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis

(2016) Pooja Gopal et al.   ACS Infectious Diseases

TRANSIT - A Software Tool for Himar1 TnSeq Analysis

(2015) Michael A. DeJesus et al.   PLoS Computational Biology

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis

(2014) Stephen H. Gillespie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement

(2014) Bruce J. Walker et al.   PLoS One

Identification and characterization of the genetic changes responsible for the characteristic smooth-to-rough morphotype alterations of clinically persistentMycobacterium abscessus

(2013) Alexandre Pawlik et al.   MOLECULAR MICROBIOLOGY

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

(2013) Y. Wakamoto et al.   SCIENCE

Two New Rapid SNP-Typing Methods for Classifying Mycobacterium tuberculosis Complex into the Main Phylogenetic Lineages

(2012) David Stucki et al.   PLoS One

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

(2011) Kristin N. Adams et al.   CELL

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

(2011) B. B. Aldridge et al.   SCIENCE

Metabolic Regulation of Mycobacterial Growth and Antibiotic Sensitivity

(2011) Seung-Hun Baek et al.   PLOS BIOLOGY

Human Base Excision Repair Creates a Bias Toward −1 Frameshift Mutations

(2010) Derek M. Lyons et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phylogeographical particularity of the Mycobacterium tuberculosis Beijing family in South Korea based on international comparison with surrounding countries

(2010) H. Y. Kang et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Simultaneous Analysis of Multiple Mycobacterium tuberculosis Knockdown Mutants In Vitro and In Vivo

(2010) Antje Blumenthal et al.   PLoS One

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

(2010) Kevin Pethe et al.   Nature Communications

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Mycolic Acid Cyclopropanation is Essential for Viability, Drug Resistance, and Cell Wall Integrity of Mycobacterium tuberculosis

(2009) Daniel Barkan et al.   CHEMISTRY & BIOLOGY

Stabilization of the genome of the mismatch repair deficient Mycobacterium tuberculosis by context-dependent codon choice

(2008) Roger M. Wanner et al.   BMC GENOMICS

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA