Proton pump inhibitors and dysbiosis: Current knowledge and aspects to be clarified

Review article: dietary fibre in the era of microbiome science

(2019) John O’Grady et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Human oral microbiota and its modulation for oral health

(2018) Yangheng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

The Intestinal Microbiota in Colorectal Cancer

(2018) Herbert Tilg et al.   CANCER CELL

Maintenance proton pump inhibition therapy and risk of oesophageal cancer

(2018) Nele Brusselaers et al.   Cancer Epidemiology

Adverse outcomes of long-term use of proton pump inhibitors

(2018) Md.Mohaimenul Islam et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Associations among Gastric Juice pH, Atrophic Gastritis, Intestinal Metaplasia and Helicobacter pylori Infection

(2018) Jihee Sung et al.   Gut and Liver

The influence of long-term use of proton pump inhibitors on the gut microbiota: an age-sex-matched case-control study

(2018) Tomohisa Takagi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Oral microbiome alterations of healthy volunteers with proton pump inhibitor

(2018) Tsuyoshi Mishiro et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplantation

(2018) Zhao-Hua Shen et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Species Level Description of the Human Ileal Bacterial Microbiota

(2018) Heidi Cecilie Villmones et al.   Scientific Reports

Association of proton pump inhibitors with the risk of hepatic encephalopathy during hospitalization for liver cirrhosis

(2018) Jia Zhu et al.   United European Gastroenterology Journal

Coprescribing proton-pump inhibitors with nonsteroidal anti-inflammatory drugs: risks versus benefits

(2018) Kok-Ann Gwee et al.   Journal of Pain Research

Fusobacterium nucleatum and colorectal cancer: A review

(2018) Fu-Mei Shang et al.   World Journal of Gastrointestinal Oncology

Helicobacter pylori Infection and Gastric Dysbiosis: Can Probiotics Administration Be Useful to Treat This Condition?

(2018) Giovanni Bruno et al.   Canadian Journal of Infectious Diseases & Medical Microbiology

Proton Pump Inhibitors: Risks and Rewards and Emerging Consequences to the Gut Microbiome

(2018) Amandeep Singh et al.   NUTRITION IN CLINICAL PRACTICE

Proton pump inhibitors are associated to minimal and overt hepatic encephalopathy and increase mortality in cirrhotics

(2018) Silvia Nardelli et al.   HEPATOLOGY

Gut Microbiome Dysbiosis and Immunometabolism: New Frontiers for Treatment of Metabolic Diseases

(2018) José E. Belizário et al.   MEDIATORS OF INFLAMMATION

Gut microbiota and colorectal cancer

(2017) R. Gao et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Mucosal microbiome dysbiosis in gastric carcinogenesis

(2017) Olabisi Oluwabukola Coker et al.   GUT

Long-term proton pump inhibitors and risk of gastric cancer development after treatment forHelicobacter pylori: a population-based study

(2017) Ka Shing Cheung et al.   GUT

Gastric microbial community profiling reveals a dysbiotic cancer-associated microbiota

(2017) Rui M Ferreira et al.   GUT

Proton-pump inhibitors: understanding the complications and risks

(2017) Peter Malfertheiner et al.   Nature Reviews Gastroenterology & Hepatology

Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis

(2017) Anca Trifan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden

(2017) Nele Brusselaers et al.   BMJ Open

Comparison of the human gastric microbiota in hypochlorhydric states arising as a result of Helicobacter pylori-induced atrophic gastritis, autoimmune atrophic gastritis and proton pump inhibitor use

(2017) Bryony N. Parsons et al.   PLoS Pathogens

Proteobacteria: A Common Factor in Human Diseases

(2017) G. Rizzatti et al.   Biomed Research International

Linking Gut Microbiota to Colorectal Cancer

(2017) Hans Raskov et al.   Journal of Cancer

The esophageal microbiota in health and disease

(2016) Vincenzo Di Pilato et al.   Annals of the New York Academy of Sciences

The human gastrointestinal tract and oral microbiota in inflammatory bowel disease: a state of the science review

(2016) Rosario Lucas López et al.   APMIS

Effects of Proton Pump Inhibitors on the Gastric Mucosa-Associated Microbiota in Dyspeptic Patients

(2016) Francesco Paroni Sterbini et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Effective and safe proton pump inhibitor therapy in acid-related diseases – A position paper addressing benefits and potential harms of acid suppression

(2016) Carmelo Scarpignato et al.   BMC Medicine

Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis

(2016) Kensuke Yamamura et al.   CLINICAL CANCER RESEARCH

Dyspepsia and the microbiome: time to focus on the small intestine

(2016) Laurie Zhong et al.   GUT

Management ofHelicobacter pyloriinfection—the Maastricht V/Florence Consensus Report

(2016) P Malfertheiner et al.   GUT

Proton pump inhibitors as a risk factor for hepatic encephalopathy and spontaneous bacterial peritonitis in patients with cirrhosis with ascites

(2016) Gitte Dam et al.   HEPATOLOGY

Current Understanding of Dysbiosis in Disease in Human and Animal Models

(2016) Arianna K. DeGruttola et al.   INFLAMMATORY BOWEL DISEASES

Proton-pump inhibitors adverse effects: a review of the evidence and position statement by the Sociedad Española de Patología Digestiva

(2016) Cristóbal de la Coba Ortiz et al.   REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS

Microbiome and potential targets for chemoprevention of esophageal adenocarcinoma

(2016) Antonio Galvao Neto et al.   SEMINARS IN ONCOLOGY

Effect of probiotics on small intestinal bacterial overgrowth in patients with gastric and colorectal cancer

(2016) Sufang Liang et al.   Turkish Journal of Gastroenterology

Is irritable bowel syndrome an infectious disease?

(2016) John Richard Thompson   WORLD JOURNAL OF GASTROENTEROLOGY

Gut microbiota role in irritable bowel syndrome: New therapeutic strategies

(2016) Eleonora Distrutti et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Extending colonic mucosal microbiome analysis—assessment of colonic lavage as a proxy for endoscopic colonic biopsies

(2016) Euan Watt et al.   Microbiome

ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus

(2015) Nicholas J Shaheen et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial

(2015) Daniel E. Freedberg et al.   GASTROENTEROLOGY

Proton pump inhibitors affect the gut microbiome

(2015) Floris Imhann et al.   GUT

Proton pump inhibitors alter the composition of the gut microbiota

(2015) Matthew A Jackson et al.   GUT

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

NSAID enteropathy and bacteria: a complicated relationship

(2015) Stephanie D. Syer et al.   JOURNAL OF GASTROENTEROLOGY

Is Campylobacter to esophageal adenocarcinoma as Helicobacter is to gastric adenocarcinoma?

(2015) Nadeem O. Kaakoush et al.   TRENDS IN MICROBIOLOGY

Recent developments in the pathophysiology of irritable bowel syndrome

(2015) Magdy El-Salhy   WORLD JOURNAL OF GASTROENTEROLOGY

What are the effects of proton pump inhibitors on the small intestine?

(2015) Shunji Fujimori   WORLD JOURNAL OF GASTROENTEROLOGY

Role of the normal gut microbiota

(2015) Sai Manasa Jandhyala   WORLD JOURNAL OF GASTROENTEROLOGY

Influence of Proton-Pump Inhibitors on the Luminal Microbiota in the Gastrointestinal Tract

(2015) Ayumi Tsuda et al.   Clinical and Translational Gastroenterology

Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota

(2014) Rory W Blackler et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Impact of Proton Pump Inhibitors on the Human Gastrointestinal Microbiome

(2014) Daniel E. Freedberg et al.   CLINICS IN LABORATORY MEDICINE

Fusobacterium nucleatum associates with stages of colorectal neoplasia development, colorectal cancer and disease outcome

(2014) L. Flanagan et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study Of Liver Diseases and the European Association for the Study of the Liver

(2014) Hendrik Vilstrup et al.   HEPATOLOGY

Nonsteroidal Anti-inflammatory Drugs, Proton Pump Inhibitors, and Gastrointestinal Injury: Contrasting Interactions in the Stomach and Small Intestine

(2014) Wojciech Marlicz et al.   MAYO CLINIC PROCEEDINGS

A Clinician's Primer on the Role of the Microbiome in Human Health and Disease

(2014) Sahil Khanna et al.   MAYO CLINIC PROCEEDINGS

The gut microbiota era marches on

(2014) Francisco Guarner   Nature Reviews Gastroenterology & Hepatology

Gastroesophageal Reflux in Relation to Adenocarcinomas of the Esophagus: A Pooled Analysis from the Barrett’s and Esophageal Adenocarcinoma Consortium (BEACON)

(2014) Michael B. Cook et al.   PLoS One

The gut microbiota and inflammatory bowel disease

(2014) Katsuyoshi Matsuoka et al.   Seminars in Immunopathology

History ofHelicobacter pylori, duodenal ulcer, gastric ulcer and gastric cancer

(2014) David Y Graham   WORLD JOURNAL OF GASTROENTEROLOGY

Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials

(2014) A. C. Ford et al.   BMJ-British Medical Journal

Acquiring and maintaining a normal oral microbiome: current perspective

(2014) Egija Zaura et al.   Frontiers in Cellular and Infection Microbiology

Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barrett's and oesophageal carcinoma: association or causality?

(2013) K. L. Blackett et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Gastric microbiota is altered in oesophagitis and Barrett's oesophagus and further modified by proton pump inhibitors

(2013) Itay Amir et al.   ENVIRONMENTAL MICROBIOLOGY

A decrease of the butyrate-producing speciesRoseburia hominisandFaecalibacterium prausnitziidefines dysbiosis in patients with ulcerative colitis

(2013) Kathleen Machiels et al.   GUT

Acid-suppressive medications and risk of oesophageal adenocarcinoma in patients with Barrett's oesophagus: a systematic review and meta-analysis

(2013) Siddharth Singh et al.   GUT

The Duodenal Microbiota Composition of Adult Celiac Disease Patients Is Associated with the Clinical Manifestation of the Disease

(2013) Pirjo Wacklin et al.   INFLAMMATORY BOWEL DISEASES

Mobile Microbiome

(2013) Y.W. Han et al.   JOURNAL OF DENTAL RESEARCH

Altered profile of human gut microbiome is associated with cirrhosis and its complications

(2013) Jasmohan S. Bajaj et al.   JOURNAL OF HEPATOLOGY

Human Gut Microbiome and Risk for Colorectal Cancer

(2013) Jiyoung Ahn et al.   JNCI-Journal of the National Cancer Institute

Acid suppressive drugs and gastric cancer: A meta-analysis of observational studies

(2013) Jeong Soo Ahn   WORLD JOURNAL OF GASTROENTEROLOGY

The use of proton pump inhibitors in treating and preventing NSAID-induced mucosal damage

(2013) James M Scheiman   ARTHRITIS RESEARCH & THERAPY

Colorectal Cancer: Looking for Answers in the Microbiota

(2013) Christian Jobin   Cancer Discovery

Recent insights into the pathogenesis of hepatic encephalopathy and treatments

(2013) Jonathan P Sturgeon et al.   Expert Review of Gastroenterology & Hepatology

Drugs that inhibit gastric acid secretion may alter the course of inflammatory bowel disease

(2012) P. Juillerat et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Clostridium difficile-Associated Diarrhea and Proton Pump Inhibitor Therapy: A Meta-Analysis

(2012) Sailajah Janarthanan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Oral microbiome and oral and gastrointestinal cancer risk

(2012) Jiyoung Ahn et al.   CANCER CAUSES & CONTROL

Molecular Pathways: Pathogenesis and Clinical Implications of Microbiome Alteration in Esophagitis and Barrett Esophagus

(2012) L. Yang et al.   CLINICAL CANCER RESEARCH

Proton Pump Inhibitor Use and the Risk of Small Intestinal Bacterial Overgrowth: A Meta-analysis

(2012) Wai–Kit Lo et al.   Clinical Gastroenterology and Hepatology

IBD—what role do Proteobacteria play?

(2012) Indrani Mukhopadhya et al.   Nature Reviews Gastroenterology & Hepatology

Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

(2012) Nicola Segata et al.   GENOME BIOLOGY

Systematic review: the use of proton pump inhibitors and increased susceptibility to enteric infection

(2011) C. Bavishi et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis

(2011) John L. Wallace et al.   GASTROENTEROLOGY

Intestinal microbiota in human health and disease: the impact of probiotics

(2011) Jacoline Gerritsen et al.   Genes and Nutrition

A randomised trial of sheathed versus standard forceps for obtaining uncontaminated biopsy specimens of microbiota from the terminal ileum

(2011) M. Dave et al.   GUT

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

(2011) M. Joossens et al.   GUT

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Gut Microbiota and Inflammation

(2011) Asa Hakansson et al.   Nutrients

Proton-pump inhibitors for the treatment of functional dyspepsia

(2011) Hidekazu Suzuki et al.   Therapeutic Advances in Gastroenterology

Use of acid-suppressive drugs and risk of pneumonia: a systematic review and meta-analysis

(2010) C.-S. Eom et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

The Human Oral Microbiome

(2010) F. E. Dewhirst et al.   JOURNAL OF BACTERIOLOGY

Role of small intestinal bacterial overgrowth and delayed gastrointestinal transit time in cirrhotic patients with minimal hepatic encephalopathy

(2010) Ankur Gupta et al.   JOURNAL OF HEPATOLOGY

Small intestinal bacterial overgrowth syndrome

(2010) Jan Bures   WORLD JOURNAL OF GASTROENTEROLOGY

Review article: small intestinal bacterial overgrowth, bile acid malabsorption and gluten intolerance as possible causes of chronic watery diarrhoea

(2009) X. FAN et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Do NSAIDs, Antibiotics, Infections, or Stress Trigger Flares in IBD?

(2009) Sunny Singh et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Stress-related modulation of inflammation in experimental models of bowel disease and post-infectious irritable bowel syndrome: Role of corticotropin-releasing factor receptors

(2009) Cornelia Kiank et al.   BRAIN BEHAVIOR AND IMMUNITY

Medication Usage and the Risk of Neoplasia in Patients With Barrett's Esophagus

(2009) Dang M. Nguyen et al.   Clinical Gastroenterology and Hepatology

Helicobacter pylori and gastric carcinogenesis

(2009) Masanori Hatakeyama   JOURNAL OF GASTROENTEROLOGY

Proton Pump Inhibitors and the Risk of Colorectal Cancer

(2008) Eva M. van Soest et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Bacterial Overgrowth and Irritable Bowel Syndrome: Unifying Hypothesis or a Spurious Consequence of Proton Pump Inhibitors?

(2008) Brennan M.R. Spiegel et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Postinfectious Irritable Bowel Syndrome

(2008) C. D. Ericsson et al.   CLINICAL INFECTIOUS DISEASES

The efficacy of probiotics in the treatment of irritable bowel syndrome: a systematic review

(2008) P. Moayyedi et al.   GUT

Comparative Analysis of Human Gut Microbiota by Barcoded Pyrosequencing

(2008) Anders F. Andersson et al.   PLoS One