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Title
Proton-pump inhibitors: understanding the complications and risks
Authors
Keywords
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Journal
Nature Reviews Gastroenterology & Hepatology
Volume 14, Issue 12, Pages 697-710
Publisher
Springer Nature
Online
2017-10-10
DOI
10.1038/nrgastro.2017.117
References
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- (2015) Chiara Melloni et al.
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- (2011) D L Worthley et al. GUT
- Familial fundic gland polyposis with gastric cancer
- (2011) Ritsuko Yanaru-Fujisawa et al. GUT
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- (2010) D. Keszthelyi et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
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- (2010) C.-S. Eom et al. CANADIAN MEDICAL ASSOCIATION JOURNAL
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- (2010) Lucio Lombardo et al. Clinical Gastroenterology and Hepatology
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