Article
Clinical Neurology
Marcantonio M. Spada, Ana Niksevic, Daniel C. Kolubinski, Alessia Offredi, Simona Giuri, Antonella Gemelli, Alessandra Brugnoni, Andrea Ferrari, Gabriele Caselli
Summary: Research on metacognitions and repetitive negative thinking in patients with Personality Disorder is limited, but findings suggest that these factors differ between patients with PD and those without PD, with metacognitions playing a role in predicting repetitive negative thinking in patients with PD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Multidisciplinary
Gabriel Martin-Gagnon, Lina Normandin, Peter Fonagy, Karin Ensink
Summary: This study found that childhood emotional abuse is associated with adolescent borderline personality features, depression, and anxiety symptoms. Uncertainty/confusion about mental states mediates the relationships between childhood emotional abuse and these outcomes.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Clinical Neurology
Karen Kelley, Maggie Walgren, Hilary L. DeShong
Summary: This study found that anger rumination is the strongest predictor of both antisocial and borderline symptoms, while worry negatively predicts antisocial symptoms. Rumination and worry explain far more variance in borderline symptoms compared to antisocial symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Terezie Sedlinska, Christiane Muehle, Tanja Richter-Schmidinger, Christian Weinland, Johannes Kornhuber, Bernd Lenz
Summary: The study found that depressed patients with high Male-DS scores exhibited stronger Cluster B personality traits, suggesting that these traits may represent a premorbid risk factor for Male-DS. Further prospective research is needed to confirm this relationship.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Linda Steinholtz, Johan Reutfors, Lena Brandt, Pia Nordanskog, Elin Thornblom, Jonas Persson, Robert Boden
Summary: Response rates to electroconvulsive therapy in depression may be lower in patients with concurrent personality or anxiety disorders, but the majority of patients still respond positively. The impact of comorbidity decreases with higher age and severity of depressive episode; subjective ratings of memory impairment do not differ between patients with and without comorbidity.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Neurosciences
Ignazio S. Piras, Giulia Braccagni, Matthew J. Huentelman, Marco Bortolato
Summary: This study is the first to use RNA sequencing to examine the molecular mechanisms underlying antisocial personality disorder (ASPD) and conduct disorder (CD). The results suggest that these disorders are associated with alterations in the orbitofrontal cortex, including downregulation of excitatory neuron transcripts and upregulation of astrocyte transcripts, as well as modifications in synaptic regulation and glutamatergic neurotransmission pathways.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Editorial Material
Psychology, Clinical
Jean-Paul Selten
Summary: This paper examines the validity of the hubris syndrome, including clinical description, laboratory study, and excluding other disorders. The research suggests that the hubris syndrome may be a non-organic personality change that occurs after individuals gain substantial power or achieve overwhelming success.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Clinical Neurology
Gulay Tasci, Suheda Kaya, Mehmet Kalayci, Murad Atmaca
Summary: This study compared the levels of acyl ghrelin (AG), des-acyl ghrelin (DAG), and leptin in patients with antisocial personality disorder (ASPD) and healthy controls. The results showed that AG and DAG levels were significantly higher in patients, while leptin levels were significantly lower. There was also a positive correlation between AG and DAG levels and impulsivity and aggression.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Multidisciplinary
Brenda De Wit-De Visser, Madeleine Rijckmans, Jeroen K. Vermunt, Arno van Dam
Summary: ASPD and ASB have significant impacts on individuals, their environment, and society, with no evidence-based treatments currently available. Contradictory research findings on therapy effectiveness and underlying factors of ASB further fuel the debate on the accuracy of the conceptualization of ASPD and the homogeneity of this population.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Behavioral Sciences
Wolfgang Retz, Ylva Ginsberg, Daniel Turner, Steffen Barra, Petra Retz-Junginger, Henrik Larsson, Phil Asherson
Summary: ADHD is closely linked to the development of conduct problems during socialization in early life and to an increased risk for antisocial activities and delinquency over the lifespan. The interaction between ADHD and common comorbid disorders like substance use disorders as well as changing environmental conditions could mediate the course of antisocial and delinquent behavior with increasing age. However, this complex interaction is only partially understood so far.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Charlotte Skoglund, Annika Tiger, Christian Ruck, Predrag Petrovic, Philip Asherson, Clara Hellner, David Mataix-Cols, Ralf Kuja-Halkola
Summary: Family and twin studies have shown that Borderline Personality Disorder (BPD) has familial aggregation and genetic propensity, with an estimated heritability of 46%. Unique environmental factors play a role in the remaining variance of BPD risk.
MOLECULAR PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Ana De la Rosa-Caceres, Marta Narvaez-Camargo, Andrea Blanc-Molina, Nehemias Romero-Perez, Daniel Dacosta-Sanchez, Bella Maria Gonzalez-Ponce, Alberto Parrado-Gonzalez, Lidia Torres-Rosado, Cinta Mancheno-Velasco, Oscar Martin Lozano-Rojas
Summary: This study analyzed the association between personality facets in the Alternative Model of Personality Disorder (AMPD) of DSM-5 and the diagnostic criteria of alcohol-use disorder (AUD). The results showed that risk taking, callousness, and irresponsibility facets had the strongest association with AUD criteria, bridging externalizing personality traits with AUD criteria.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Clinical Neurology
Elena Scumaci, Enrica Marzola, Giovanni Abbate-Daga, Marianna Pellegrini, Valentina Ponzo, Ilaria Goitre, Andrea Benso, Fabio Broglio, Sara Belcastro, Chiara Crespi, Chiara D'Eusebio, Franco De Michieli, Ezio Ghigo, Simona Bo
Summary: The study found that many outpatient with obesity reported symptoms of anxiety and depression even without a formal psychiatric diagnosis. Cyclothymic temperament was positively associated with binge eating, while hyperthymic temperament showed a protective effect on both binge eating and multiple weight cycling.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Xueting Wang, Weili Zhan, Ling Huang, Yunmei Guo, Yousha Wang, Huiwen Tan, Lianhong Wang
Summary: This study aimed to investigate the effects of anxiety and depression on health-related quality of life (HRQOL) in patients after severe acute pancreatitis (SAP) using structural equation modeling. The results showed that both anxiety and depression have a direct negative impact on HRQOL, and anxiety also indirectly affects HRQOL through depression. Regular assessment and management of anxiety and depression are necessary for SAP patients to improve their HRQOL more effectively.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Carlotta Lunghi, Lionel Cailhol, Victoria Massamba, Elhadji A. Laouan Sidi, Caroline Sirois, Elham Rahme, Louis Rochette, Suzane Renaud, Evens Villeneuve, Marion Koch, Robert Biskin, Cathy Martineau, Philippe Vincent, Pierre David, Alain Lesage
Summary: Psychotropic medication use is common among individuals with Cluster B personality disorders, with an increase in usage observed after diagnosis, especially for antipsychotics, antidepressants, and mood stabilizers.
FRONTIERS IN PSYCHIATRY
(2023)