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Known structures and unknown mechanisms of TMEM16 scramblases and channels

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Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation

(2018) Masaki Tsuchiya et al.   Nature Communications

Characterization of the scrambling domain of the TMEM16 family

(2017) Sayuri Gyobu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells

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Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4

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Atomistic insight into lipid translocation by a TMEM16 scramblase

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Polyphosphoinositide binding domains: Key to inositol lipid biology

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Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase

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Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate

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PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts

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Asymmetrical Distribution of Choline Phospholipids Revealed by Click Chemistry and Freeze-Fracture Electron Microscopy

(2014) Shohei Iyoshi et al.   ACS Chemical Biology

Microscopic Methods to Observe the Distribution of Lipids in the Cellular Membrane

(2014) Sho Takatori et al.   BIOCHEMISTRY

ANO10 mutations cause ataxia and coenzyme Q10 deficiency

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Lipid landscapes and pipelines in membrane homeostasis

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Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine

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Role of Flippases, Scramblases and Transfer Proteins in Phosphatidylserine Subcellular Distribution

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Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries

(2014) Jinglei Cheng et al.   Nature Communications

Autosomal Recessive Cerebellar Ataxia Type 3 Due toANO10Mutations

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Calcium-dependent Phospholipid Scramblase Activity of TMEM16 Protein Family Members

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Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

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Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

(2013) Mattia Malvezzi et al.   Nature Communications

Phosphatidylserine dynamics in cellular membranes

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High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

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Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes

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Targeted Next-Generation Sequencing of a 12.5 Mb Homozygous Region Reveals ANO10 Mutations in Patients with Autosomal-Recessive Cerebellar Ataxia

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Recessive Mutations in the Putative Calcium-Activated Chloride Channel Anoctamin 5 Cause Proximal LGMD2L and Distal MMD3 Muscular Dystrophies

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A founder mutation in Anoctamin 5 is a major cause of limb girdle muscular dystrophy

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Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Quantitative electron microscopy for the nanoscale analysis of membrane lipid distribution

(2010) Akikazu Fujita et al.   Nature Protocols

A new distal myopathy with mutation in anoctamin 5

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Purification and characterization of human phosphatidylserine synthases 1 and 2

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Membrane lipids: where they are and how they behave

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Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

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