The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway
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Title
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway
Authors
Keywords
Apoptosis, Autophagic cell death, Esophageal cancer, Cancer treatment, Cell cycle and cell division, Mouse models, Cell staining, Protein expression
Journal
PLoS One
Volume 14, Issue 5, Pages e0216759
Publisher
Public Library of Science (PLoS)
Online
2019-05-16
DOI
10.1371/journal.pone.0216759
References
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- (2017) Kwang-Youn Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2017) Shuling Song et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Dihydromyricetin induces mitochondria-mediated apoptosis in HepG2 cells through down-regulation of the Akt/Bad pathway
- (2017) Zhuangwei Zhang et al. NUTRITION RESEARCH
- Antitumor and immunomodulatory effects of ginsenoside Rh2 and its octyl ester derivative in H22 tumor-bearing mice
- (2017) Fang Chen et al. Journal of Functional Foods
- Anticancer effects of ginsenoside Rk3 on non-small cell lung cancer cells: in vitro and in vivo
- (2017) Zhiguang Duan et al. Food & Function
- Cancer treatment and survivorship statistics, 2016
- (2016) Kimberly D. Miller et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy
- (2016) Dongxu Fu et al. DIABETOLOGIA
- Emerging immunotherapy for the treatment of esophageal cancer
- (2016) SeungJu Jackie Oh et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways
- (2016) Yashi Mi et al. FREE RADICAL BIOLOGY AND MEDICINE
- p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome
- (2016) Victoria Cohen-Kaplan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stellettin B Induces G1 Arrest, Apoptosis and Autophagy in Human Non-small Cell Lung Cancer A549 Cells via Blocking PI3K/Akt/mTOR Pathway
- (2016) Ran Wang et al. Scientific Reports
- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Recent Advances From Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma
- (2015) Shinya Ohashi et al. GASTROENTEROLOGY
- Current Status of Management of Malignant Disease: Current Management of Esophageal Cancer
- (2015) Jonathan Cools-Lartigue et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway
- (2013) Dhruv Kumar et al. CANCER LETTERS
- The role of cell signalling in the crosstalk between autophagy and apoptosis
- (2013) Laurence A. Booth et al. CELLULAR SIGNALLING
- Cdks, cyclins and CKIs: roles beyond cell cycle regulation
- (2013) S. Lim et al. DEVELOPMENT
- Beclin-1: Autophagic regulator and therapeutic target in cancer
- (2013) Lei-lei Fu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Emerging regulation and functions of autophagy
- (2013) Patricia Boya et al. NATURE CELL BIOLOGY
- Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer
- (2012) Wiem Chaabane et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- G1/S transcription and the DNA synthesis checkpoint: Common regulatory mechanisms
- (2011) Tsvetomira Ivanova et al. CELL CYCLE
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