Bailcalin Protects against Diabetic Cardiomyopathy through Keap1/Nrf2/AMPK-Mediated Antioxidative and Lipid-Lowering Effects

Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway

(2018) Yichuan Xiao et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Abnormal Myocardial Dietary Fatty Acid Metabolism and Diabetic Cardiomyopathy

(2018) André C. Carpentier   CANADIAN JOURNAL OF CARDIOLOGY

Baicalin reduces blood lipids and inflammation in patients with coronary artery disease and rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial

(2018) Yuanxing Hang et al.   Lipids in Health and Disease

Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

(2018) Antonio Cuadrado et al.   PHARMACOLOGICAL REVIEWS

Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system

(2018) Guang Wang et al.   Cell Death & Disease

Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling

(2018) Zhou Wang et al.   Cell Death & Disease

Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart

(2018) Hong Yang et al.   Cell Death & Disease

Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway

(2018) Ying Xin et al.   Redox Biology

Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction

(2018) Yuan Liu et al.   Redox Biology

Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes

(2018) Aidin Rawshani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Baicalin provides neuroprotection in traumatic brain injury mice model through Akt/Nrf2 pathway

(2018) Jiang Fang et al.   Drug Design Development and Therapy

Diabetic cardiomyopathy: molecular mechanisms, detrimental effects of conventional treatment, and beneficial effects of natural therapy

(2018) Brahmanaidu Parim et al.   HEART FAILURE REVIEWS

Baicalin attenuates in vivo and in vitro hyperglycemia-exacerbated ischemia/reperfusion injury by regulating mitochondrial function in a manner dependent on AMPK

(2017) Shanshan Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Reactive oxygen species signalling in the diabetic heart: emerging prospect for therapeutic targeting

(2017) Adam J Wilson et al.   HEART

Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1

(2017) Hai-han Liao et al.   Oxidative Medicine and Cellular Longevity

Baicalin Ameliorates Liver Injury Induced by Chronic plus Binge Ethanol Feeding by Modulating Oxidative Stress and Inflammation via CYP2E1 and NRF2 in Mice

(2017) Ping He et al.   Oxidative Medicine and Cellular Longevity

Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway

(2017) Jialin Duan et al.   Scientific Reports

Lipid metabolism and signaling in cardiac lipotoxicity

(2016) Kenneth D'Souza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Novel protective mechanism of reducing renal cell damage in diabetes: Activation AMPK by AICAR increased NRF2/OGG1 proteins and reduced oxidative DNA damage

(2016) Samy L. Habib et al.   CELL CYCLE

Mnk1 (Mitogen-Activated Protein Kinase–Interacting Kinase 1) Deficiency Aggravates Cardiac Remodeling in MiceNovelty and Significance

(2016) Yuan Yuan et al.   HYPERTENSION

Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

(2016)   LANCET

AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550

(2016) Min Sung Joo et al.   MOLECULAR AND CELLULAR BIOLOGY

Is AMPK the savior of the failing heart?

(2015) Ty T. Kim et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway

(2014) Zhiguo Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Diabetic Cardiomyopathy and Its Prevention by Nrf2: Current Status

(2014) Jing Chen et al.   Diabetes & Metabolism Journal

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

(2011) Y. Tan et al.   DIABETES

Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy

(2010) Mohanraj Rajesh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Resveratrol Prevents the Prohypertrophic Effects of Oxidative Stress on LKB1

(2009) Vernon W. Dolinsky et al.   CIRCULATION

The PPARα-PGC-1αAxis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium

(2007) Jennifer G. Duncan et al.   PPAR Research