Baicalin Ameliorates Liver Injury Induced by Chronic plus Binge Ethanol Feeding by Modulating Oxidative Stress and Inflammation via CYP2E1 and NRF2 in Mice

Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders

(2017) Biswanath Dinda et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis

(2017) Partha Mukhopadhyay et al.   JOURNAL OF HEPATOLOGY

Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice

(2016) Terence N. Bukong et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats

(2016) Huifen Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Baicalin attenuates inflammation in mice with OVA-induced asthma by inhibiting NF-κB and suppressing CCR7/CCL19/CCL21

(2016) Jiaqi Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice

(2016) XIN-MIN DING et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Oxidative Stress and Liver Cancer: Etiology and Therapeutic Targets

(2016) Zhanpeng Wang et al.   Oxidative Medicine and Cellular Longevity

Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients

(2016) Marina Galicia-Moreno et al.   Oxidative Medicine and Cellular Longevity

Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury

(2016) Ravirajsinh N. Jadeja et al.   Oxidative Medicine and Cellular Longevity

Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?

(2016) Tarique Hussain et al.   Oxidative Medicine and Cellular Longevity

Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

(2016) Lucio G. Costa et al.   Oxidative Medicine and Cellular Longevity

Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?

(2016) Christine A. Houghton et al.   Oxidative Medicine and Cellular Longevity

TNF and ROS Crosstalk in Inflammation

(2016) Heiko Blaser et al.   TRENDS IN CELL BIOLOGY

Baicalin Attenuates IL-17-Mediated Acetaminophen-Induced Liver Injury in a Mouse Model

(2016) Chia-Chih Liao et al.   PLoS One

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway

(2015) Youli Xi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Glycycoumarin ameliorates alcohol-induced hepatotoxicity via activation of Nrf2 and autophagy

(2015) Xinhua Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

The involvement of p62–Keap1–Nrf2 antioxidative signaling pathway and JNK in the protection of natural flavonoid quercetin against hepatotoxicity

(2015) Li-Li Ji et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans

(2015) Ming-Jiang Xu et al.   GASTROENTEROLOGY

Advances in alcoholic liver disease: An update on alcoholic hepatitis

(2015) Randy Liang   WORLD JOURNAL OF GASTROENTEROLOGY

Autophagy-induced RelB/p52 activation mediates tumour-associated macrophage repolarisation and suppression of hepatocellular carcinoma by natural compound baicalin

(2015) H-Y Tan et al.   Cell Death & Disease

Circulating Lipids Are Associated with Alcoholic Liver Cirrhosis and Represent Potential Biomarkers for Risk Assessment

(2015) Peter J. Meikle et al.   PLoS One

Baicalein, a Bioflavonoid, Prevents Cisplatin-Induced Acute Kidney Injury by Up-Regulating Antioxidant Defenses and Down-Regulating the MAPKs and NF-κB Pathways

(2015) Bidya Dhar Sahu et al.   PLoS One

Baicalein modulates Nrf2/Keap1 system in both Keap1-dependent and Keap1-independent mechanisms

(2014) Si Qin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ameliorative Effect of Fisetin on Cisplatin-Induced Nephrotoxicity in Rats via Modulation of NF-κB Activation and Antioxidant Defence

(2014) Bidya Dhar Sahu et al.   PLoS One

Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2

(2013) Ludmila F.M.F. Cardozo et al.   BIOCHIMIE

Baicalein 6-O-β-d-Glucopyranuronoside Is a Main Metabolite in the Plasma after Oral Administration of Baicalin, a Flavone Glucuronide of Scutellariae Radix, to Rats

(2013) Teruaki Akao et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: A critical role for E-selectin

(2013) Adeline Bertola et al.   HEPATOLOGY

Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis

(2013) Partha Mukhopadhyay et al.   HEPATOLOGY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Inflammation in Alcoholic Liver Disease

(2012) H. Joe Wang et al.   Annual Review of Nutrition

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis

(2012) Saurabh Chatterjee et al.   JOURNAL OF HEPATOLOGY

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

(2010) Sung Hwan Ki et al.   HEPATOLOGY

Baicalin Improves Antioxidant Status of Streptozotocin-Induced Diabetic Wistar Rats

(2009) Viduranga Y. Waisundara et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Protective Effect of Baicalin Against Carbon Tetrachloride–Induced Acute Hepatic Injury in Mice

(2008) Sang-Won Park et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

CYP2E1 and oxidative liver injury by alcohol

(2007) Yongke Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE