Flavonoids as inducers of white adipose tissue browning and thermogenesis: signalling pathways and molecular triggers
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Title
Flavonoids as inducers of white adipose tissue browning and thermogenesis: signalling pathways and molecular triggers
Authors
Keywords
Flavonoids, Brown adipose tissue, Browning, Obesity
Journal
Nutrition & Metabolism
Volume 16, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-18
DOI
10.1186/s12986-019-0370-7
References
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Note: Only part of the references are listed.- Nobiletin induces brown adipocyte-like phenotype and ameliorates stress in 3T3-L1 adipocytes
- (2018) Jameel Lone et al. BIOCHIMIE
- Cyanidin-3-O-β-glucoside regulates the activation and the secretion of adipokines from brown adipose tissue and alleviates diet induced fatty liver
- (2018) Lei Pei et al. BIOMEDICINE & PHARMACOTHERAPY
- Browning effects of (-)-epicatechin on adipocytes and white adipose tissue
- (2017) Claudia Elena Varela et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Rutin ameliorates obesity through brown fat activation
- (2017) Xiaoxue Yuan et al. FASEB JOURNAL
- Inflammation Downregulates UCP1 Expression in Brown Adipocytes Potentially via SIRT1 and DBC1 Interaction
- (2017) Mark Nøhr et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Anti-inflammatory Activity of Natural Geranylated Flavonoids: Cyclooxygenase and Lipoxygenase Inhibitory Properties and Proteomic Analysis
- (2017) Zuzana Hanáková et al. JOURNAL OF NATURAL PRODUCTS
- A polyphenolic extract from green tea leaves activates fat browning in high-fat-diet-induced obese mice
- (2017) Audrey M. Neyrinck et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Increasing cAMP levels of preadipocytes by cyanidin-3-glucoside treatment induces the formation of beige phenotypes in 3T3-L1 adipocytes
- (2017) Toshiya Matsukawa et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Dietary flavonoids and modulation of natural killer cells: implications in malignant and viral diseases
- (2017) Markus Burkard et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Quercetin, a functional compound of onion peel, remodels white adipocytes to brown-like adipocytes
- (2017) Sang Gil Lee et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Cyanidin-3-glucoside increases whole body energy metabolism by upregulating brown adipose tissue mitochondrial function
- (2017) Yilin You et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats
- (2017) Maharshi Bhaswant et al. NUTRITION
- The anti-obesity properties of the proanthocyanidin extract from the leaves of Chinese bayberry (Myrica rubra Sieb.et Zucc.)
- (2017) Xiaozhou Zhou et al. Food & Function
- A meta-analysis of the relationship between brain dopamine receptors and obesity: a matter of changes in behavior rather than food addiction?
- (2016) D Benton et al. INTERNATIONAL JOURNAL OF OBESITY
- Thyroid hormones induce browning of white fat
- (2016) Noelia Martínez-Sánchez et al. JOURNAL OF ENDOCRINOLOGY
- Metabolic programming of a beige adipocyte phenotype by genistein
- (2016) Sadat A. Aziz et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Convertible visceral fat as a therapeutic target to curb obesity
- (2016) Antonio Giordano et al. NATURE REVIEWS DRUG DISCOVERY
- Chrysin induces brown fat–like phenotype and enhances lipid metabolism in 3T3-L1 adipocytes
- (2016) Jae Heon Choi et al. NUTRITION
- Phytochemicals as novel agents for the induction of browning in white adipose tissue
- (2016) Yusra Azhar et al. Nutrition & Metabolism
- A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet
- (2016) Noemí Arias et al. Obesity
- Evaluation of seasonal changes of triterpenic acid contents in Viscum album from different host trees
- (2016) Magdalena Wójciak-Kosior et al. PHARMACEUTICAL BIOLOGY
- White Adipose Tissue Browning: A Double-edged Sword
- (2016) Abdikarim Abdullahi et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Olive Leaf Extract from Sicilian Cultivar Reduced Lipid Accumulation by Inducing Thermogenic Pathway during Adipogenesis
- (2016) Rosa Palmeri et al. Frontiers in Pharmacology
- Silibinin Regulates Lipid Metabolism and Differentiation in Functional Human Adipocytes
- (2016) Ignazio Barbagallo et al. Frontiers in Pharmacology
- Essential role of UCP1 modulating the central effects of thyroid hormones on energy balance
- (2016) Mayte Alvarez-Crespo et al. Molecular Metabolism
- Dietary component isorhamnetin is a PPARγ antagonist and ameliorates metabolic disorders induced by diet or leptin deficiency
- (2016) Yu Zhang et al. Scientific Reports
- PPAR-α agonist elicits metabolically active brown adipocytes and weight loss in diet-induced obese mice
- (2015) Tamiris Lima Rachid et al. CELL BIOCHEMISTRY AND FUNCTION
- Brown adipose tissue: a potential target in the fight against obesity and the metabolic syndrome
- (2015) L. Poekes et al. CLINICAL SCIENCE
- Dihydromyricetin stimulates irisin secretion partially via the PGC-1α pathway
- (2015) Qicheng Zhou et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Systematic analysis of the polyphenol metabolome using the Phenol-Explorer database
- (2015) Joseph A. Rothwell et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Cyanidin 3-glucoside improves diet-induced metabolic syndrome in rats
- (2015) Maharshi Bhaswant et al. PHARMACOLOGICAL RESEARCH
- Food Ingredients as Anti-Obesity Agents
- (2015) Masayuki Saito et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Matured Hop Bittering Components Induce Thermogenesis in Brown Adipose Tissue via Sympathetic Nerve Activity
- (2015) Yumie Morimoto-Kobayashi et al. PLoS One
- Roles of PTEN (Phosphatase and Tensin Homolog) in Gastric Cancer Development and Progression
- (2014) Wen-Ting Xu et al. Asian Pacific Journal of Cancer Prevention
- Brown Alga Ecklonia cava Polyphenol Extract Ameliorates Hepatic Lipogenesis, Oxidative Stress, and Inflammation by Activation of AMPK and SIRT1 in High-Fat Diet-Induced Obese Mice
- (2014) Hyeyoon Eo et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1
- (2014) Jing Dong et al. JOURNAL OF LIPID RESEARCH
- Effects of Xanthohumol-rich Extract from the Hop on Fatty Acid Metabolism in Rats Fed a High-fat Diet
- (2014) Kazuki Yui et al. Journal of Oleo Science
- Effects of Xanthohumol-Rich Hop Extract on the Differentiation of Preadipocytes
- (2014) Ayane Kiyofuji et al. Journal of Oleo Science
- Quercetin-rich onion peel extract suppresses adipogenesis by down-regulating adipogenic transcription factors and gene expression in 3T3-L1 adipocytes
- (2014) Cho-Rong Bae et al. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
- The flavan-3-ol fraction of cocoa powder suppressed changes associated with early-stage metabolic syndrome in high-fat diet-fed rats
- (2014) Naomi Osakabe et al. LIFE SCIENCES
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- (2014) Naoki Watanabe et al. Lipids in Health and Disease
- Sudachitin, a polymethoxylated flavone, improves glucose and lipid metabolism by increasing mitochondrial biogenesis in skeletal muscle
- (2014) Rie Tsutsumi et al. Nutrition & Metabolism
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- (2014) Yoko Yamashita et al. Food & Function
- Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
- (2014) Hossein Hosseinzadeh et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- Antiobesity effects of quercetin-rich onion peel extract on the differentiation of 3T3-L1 preadipocytes and the adipogenesis in high fat-fed rats
- (2013) Jiyoung Moon et al. FOOD AND CHEMICAL TOXICOLOGY
- A Metabolomics-driven Elucidation of the Anti-obesity Mechanisms of Xanthohumol
- (2013) Jay S. Kirkwood et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A review on plant-based rutin extraction methods and its pharmacological activities
- (2013) Lee Suan Chua JOURNAL OF ETHNOPHARMACOLOGY
- Brown and beige fat: development, function and therapeutic potential
- (2013) Matthew Harms et al. NATURE MEDICINE
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- (2012) Yoko Yamashita et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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- (2012) Li Qiang et al. CELL
- Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
- (2012) Kristin I. Stanford et al. JOURNAL OF CLINICAL INVESTIGATION
- Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis inLdlr−/−mice
- (2012) Julia M. Assini et al. JOURNAL OF LIPID RESEARCH
- A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
- (2012) Pontus Boström et al. NATURE
- Monoterpenes with Analgesic Activity-A Systematic Review
- (2012) Adriana G. Guimarães et al. PHYTOTHERAPY RESEARCH
- Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
- (2011) Pablo J Fernandez-Marcos et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Chronic dietary supplementation of proanthocyanidins corrects the mitochondrial dysfunction of brown adipose tissue caused by diet-induced obesity in Wistar rats
- (2011) David Pajuelo et al. BRITISH JOURNAL OF NUTRITION
- Reduction of body weight, liver steatosis and expression of stearoyl-CoA desaturase 1 by the isoflavone daidzein in diet-induced obesity
- (2011) A Crespillo et al. BRITISH JOURNAL OF PHARMACOLOGY
- Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties
- (2011) Silvina B. Lotito et al. FREE RADICAL BIOLOGY AND MEDICINE
- A Black Soybean Seed Coat Extract Prevents Obesity and Glucose Intolerance by Up-regulating Uncoupling Proteins and Down-regulating Inflammatory Cytokines in High-Fat Diet-Fed Mice
- (2011) Yuki Kanamoto et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Brown adipose tissue and aging
- (2010) Virgile Lecoultre et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- The T3Receptor β1 Isoform Regulates UCP1 and D2 Deiodinase in Rat Brown Adipocytes
- (2010) Raquel Martinez de Mena et al. ENDOCRINOLOGY
- Dietary naringenin increases hepatic peroxisome proliferators–activated receptor α protein expression and decreases plasma triglyceride and adiposity in rats
- (2010) Kae Won Cho et al. EUROPEAN JOURNAL OF NUTRITION
- Central neural pathways for thermoregulation
- (2010) Shaun et al. Frontiers in Bioscience-Landmark
- Positive and negative control of Ucp1 gene transcription and the role of β-adrenergic signaling networks
- (2010) S Collins et al. INTERNATIONAL JOURNAL OF OBESITY
- FdC1, a Novel Ferredoxin Protein Capable of Alternative Electron Partitioning, Increases in Conditions of Acceptor Limitation at Photosystem I
- (2010) Ingo Voss et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism
- (2010) Branislav Radović et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
- (2010) Miguel López et al. NATURE MEDICINE
- Green tea catechins, caffeine and body-weight regulation
- (2010) M.S. Westerterp-Plantenga PHYSIOLOGY & BEHAVIOR
- Effects of Flavangenol on Autonomic Nerve Activities and Dietary Body Weight Gain in Rats
- (2009) Mamoru TANIDA et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli
- (2009) Soledad Miranda et al. CELLULAR SIGNALLING
- Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor-Null Mice With Diet-Induced Insulin Resistance
- (2009) E. E. Mulvihill et al. DIABETES
- Expression of Uncoupling Protein 1 in Mouse Brown Adipose Tissue Is Thyroid Hormone Receptor-β Isoform Specific and Required for Adaptive Thermogenesis
- (2009) Miriam O. Ribeiro et al. ENDOCRINOLOGY
- Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes
- (2009) Natasa Petrovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thyroid Hormone Induced Brown Adipose Tissue and Amelioration of Diabetes in a Patient with Extreme Insulin Resistance
- (2009) Monica C. Skarulis et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- C/EBP and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor Agonists
- (2009) C. Vernochet et al. MOLECULAR AND CELLULAR BIOLOGY
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Effect of 4G-α-glucopyranosyl hesperidin on brown fat adipose tissue- and cutaneous-sympathetic nerve activity and peripheral body temperature
- (2009) Jiao Shen et al. NEUROSCIENCE LETTERS
- Thermogenic effect of triiodothyroacetic acid at low doses in rat adipose tissue without adverse side effects in the thyroid axis
- (2008) G. Medina-Gomez et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Fat and Beyond: The Diverse Biology of PPARγ
- (2008) Peter Tontonoz et al. Annual Review of Biochemistry
- The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways
- (2008) Jiyun Ahn et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effects of soy protein and isoflavone on hepatic fatty acid synthesis and oxidation and mRNA expression of uncoupling proteins and peroxisome proliferator-activated receptor γ in adipose tissues of rats
- (2008) Yoko Takahashi et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Tea catechins enhance the mRNA expression of uncoupling protein 1 in rat brown adipose tissue
- (2008) Sachiko Nomura et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet
- (2008) Laura K. Stewart et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Quercetin Ameliorates Metabolic Syndrome and Improves the Inflammatory Status in Obese Zucker Rats
- (2008) Leonor Rivera et al. Obesity
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