Identification of novel components of NAD-utilizing metabolic pathways and prediction of their biochemical functions

Interaction Proteomics Identify NEURL4 and the HECT E3 Ligase HERC2 as Novel Modulators of Centrosome Architecture

(2012) Abdallah K. Al-Hakim et al.   MOLECULAR & CELLULAR PROTEOMICS

Analysis of DBC1 and its homologs suggests a potential mechanism for regulation of Sirtuin domain deacetylases by NAD metabolites

(2011) Vivek Anantharaman et al.   CELL CYCLE

Identification of Nicotinamide Mononucleotide Deamidase of the Bacterial Pyridine Nucleotide Cycle Reveals a Novel Broadly Conserved Amidohydrolase Family

(2011) Luca Galeazzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orphan Macrodomain Protein (Human C6orf130) Is anO-Acyl-ADP-ribose Deacylase

(2011) Francis C. Peterson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase

(2011) Dea Slade et al.   NATURE

A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems

(2011) Dapeng Zhang et al.   NUCLEIC ACIDS RESEARCH

Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems

(2011) Lakshminarayan M. Iyer et al.   NUCLEIC ACIDS RESEARCH

E1- and ubiquitin-like proteins provide a direct link between protein conjugation and sulfur transfer in archaea

(2011) H. V. Miranda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADP-ribosylation of arginine

(2010) Sabrina Laing et al.   AMINO ACIDS

Bacillithiol, a New Player in Bacterial Redox Homeostasis

(2010) John D. Helmann   ANTIOXIDANTS & REDOX SIGNALING

Sirtuin chemical mechanisms

(2010) Anthony A. Sauve   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis

(2010) L Aravind et al.   Biology Direct

Presence of a classical RRM-fold palm domain in Thg1-type 3'- 5'nucleic acid polymerases and the origin of the GGDEF and CRISPR polymerase domains

(2010) Vivek Anantharaman et al.   Biology Direct

Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes

(2010) Matteo Citarelli et al.   BMC EVOLUTIONARY BIOLOGY

Genomics-driven Reconstruction ofAcinetobacterNAD Metabolism

(2010) Leonardo Sorci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria

(2010) Stephanie K. Aoki et al.   NATURE

Origin and evolution of peptide-modifying dioxygenases and identification of the wybutosine hydroxylase/hydroperoxidase

(2010) L. M. Iyer et al.   NUCLEIC ACIDS RESEARCH

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans

(2010) K. A. Estes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of Sir2Tm bound to a propionylated peptide

(2010) Poonam Bheda et al.   PROTEIN SCIENCE

Nucleases: diversity of structure, function and mechanism

(2010) Wei Yang   QUARTERLY REVIEWS OF BIOPHYSICS

Photorhabdus luminescens Toxins ADP-Ribosylate Actin and RhoA to Force Actin Clustering

(2010) A. E. Lang et al.   SCIENCE

Cell-free synthesis and characterization of a novel cytotoxic pierisin-like protein from the cabbage butterfly Pieris rapae

(2010) Joachim H.C. Orth et al.   TOXICON

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase

(2009) Andrew M. Gulick   ACS Chemical Biology

Microbial NAD Metabolism: Lessons from Comparative Genomics

(2009) F. Gazzaniga et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins

(2009) Lakshminarayan M. Iyer et al.   Molecular BioSystems

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis

(2009) L. Sorci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Function of an ADP-Ribose-Dependent Transcriptional Regulator of NAD Metabolism

(2009) Nian Huang et al.   STRUCTURE

Mammalian ADP-ribosyltransferases and ADP-ribosylhydrolases

(2008) Friedrich Koch-Nolte   Frontiers in Bioscience-Landmark

A Second Pathway to Degrade Pyrimidine Nucleic Acid Precursors in Eukaryotes

(2008) Gorm Andersen et al.   JOURNAL OF MOLECULAR BIOLOGY

Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes

(2008) Vishnu Karthik Jothivasan et al.   NATURAL PRODUCT REPORTS

Transcriptional regulation of NAD metabolism in bacteria: NrtR family of Nudix-related regulators

(2008) Dmitry A. Rodionov et al.   NUCLEIC ACIDS RESEARCH

Kalign2: high-performance multiple alignment of protein and nucleotide sequences allowing external features

(2008) Timo Lassmann et al.   NUCLEIC ACIDS RESEARCH

Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr

(2008) J. Baysarowich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural history of the E1-like superfamily: Implication for adenylation, sulfur transfer, and ubiquitin conjugation

(2008) A. Maxwell Burroughs et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site

(2007) Sahil Adriouch et al.   FASEB JOURNAL

Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes

(2007) Lakshminarayan M. Iyer et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse

(2002) Gustavo Glowacki et al.   PROTEIN SCIENCE