Transgenesis in Hydra to characterize gene function and visualize cell behavior

Regionalized nervous system in Hydra and the mechanism of its development

(2019) Yukihiko Noro et al.   GENE EXPRESSION PATTERNS

Modern genomic tools reveal the structural and cellular diversity of cnidarian nervous systems

(2019) Fabian Rentzsch et al.   CURRENT OPINION IN NEUROBIOLOGY

Non-senescent Hydra tolerates severe disturbances in the nuclear lamina

(2018) Alexander Klimovich et al.   Aging-US

Rethinking the Role of the Nervous System: Lessons From the Hydra Holobiont

(2018) Alexander V. Klimovich et al.   BIOESSAYS

Real time dynamics of β-catenin expression during Hydra development, regeneration and Wnt signalling activation

(2018) Roberta Iachetta et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Metabolic co-dependence drives the evolutionarily ancient Hydra–Chlorella symbiosis

(2018) Mayuko Hamada et al.   eLife

Carrying Capacity and Colonization Dynamics of Curvibacter in the Hydra Host Habitat

(2018) Tanita Wein et al.   Frontiers in Microbiology

Stem Cell Transcription Factor FoxO Controls Microbiome Resilience in Hydra

(2018) Benedikt M. Mortzfeld et al.   Frontiers in Microbiology

Meganuclease-assisted generation of stable transgenics in the sea anemone Nematostella vectensis

(2017) Eduard Renfer et al.   Nature Protocols

Back to the Basics: Cnidarians Start to Fire

(2017) Thomas C.G. Bosch et al.   TRENDS IN NEUROSCIENCES

A secreted antibacterial neuropeptide shapes the microbiome of Hydra

(2017) René Augustin et al.   Nature Communications

Spontaneous body contractions are modulated by the microbiome of Hydra

(2017) Andrea P. Murillo-Rincon et al.   Scientific Reports

Revisiting the age, evolutionary history and species level diversity of the genus Hydra (Cnidaria: Hydrozoa)

(2015) Martin Schwentner et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

How do environmental factors influence life cycles and development? An experimental framework for early-diverging metazoans

(2014) Thomas C. G. Bosch et al.   BIOESSAYS

Robust G2 pausing of adult stem cells in Hydra

(2014) Wanda Buzgariu et al.   DIFFERENTIATION

Rethinking the role of immunity: lessons from Hydra

(2014) Thomas C.G. Bosch   TRENDS IN IMMUNOLOGY

Naturally occurring tumours in the basal metazoan Hydra

(2014) Tomislav Domazet-Lošo et al.   Nature Communications

A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra

(2013) K. M. Glauber et al.   DEVELOPMENT

Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis

(2013) Michael J Layden et al.   Nature Protocols

PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells

(2013) C. E. Juliano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct antimicrobial peptide expression determines host species-specific bacterial associations

(2013) S. Franzenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How to use Hydra as a model system to teach biology in the classroom

(2012) Patricia Bossert et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Germline stem cells and sex determination in Hydra

(2012) Chiemi Nishimiya-Fujisawa et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Hydra, a fruitful model system for 270 years

(2012) Brigitte Galliot   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Molecular Signatures of the Three Stem Cell Lineages in Hydra and the Emergence of Stem Cell Function at the Base of Multicellularity

(2012) Georg Hemmrich et al.   MOLECULAR BIOLOGY AND EVOLUTION

Hymyc1 Downregulation Promotes Stem Cell Proliferation in Hydra vulgaris

(2012) Alfredo Ambrosone et al.   PLoS One

Incorporation of a Horizontally Transferred Gene into an Operon during Cnidarian Evolution

(2012) Catherine E. Dana et al.   PLoS One

FoxO is a critical regulator of stem cell maintenance in immortal Hydra

(2012) A.-M. Boehm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers

(2012) S. Franzenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Migration of multipotent interstitial stem cells in Hydra

(2012) Anna-Marei Boehm et al.   ZOOLOGY

Characterization of taxonomically restricted genes in a phylum-restricted cell type

(2012) Sabine Milde et al.   GENOME BIOLOGY

Autoregulatory and repressive inputs localize Hydra Wnt3 to the head organizer

(2011) Y. Nakamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hydra polyp: Nothing but an active stem cell community

(2010) Thomas C. G. Bosch et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

β-catenin plays a central role in setting up the head organizer in hydra

(2010) Lydia Gee et al.   DEVELOPMENTAL BIOLOGY

Phylogeny and biogeography of Hydra (Cnidaria: Hydridae) using mitochondrial and nuclear DNA sequences

(2010) D.E. Martínez et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

The dynamic genome of Hydra

(2010) Jarrod A. Chapman et al.   NATURE

Plasticity of epithelial cell shape in response to upstream signals: A whole-organism study using transgenic Hydra

(2009) Friederike Anton-Erxleben et al.   ZOOLOGY

Compagen, a comparative genomics platform for early branching metazoan animals, reveals early origins of genes regulating stem-cell differentiation

(2008) Georg Hemmrich et al.   BIOESSAYS

FGF signalling controls formation of the apical sensory organ in the cnidarian Nematostella vectensis

(2008) F. Rentzsch et al.   DEVELOPMENT

A Novel Gene Family Controls Species-Specific Morphological Traits in Hydra

(2008) Konstantin Khalturin et al.   PLOS BIOLOGY

Cell type complexity in the basal metazoan Hydra is maintained by both stem cell based mechanisms and transdifferentiation

(2007) Stefan Siebert et al.   DEVELOPMENTAL BIOLOGY