Stem Cell Transcription Factor FoxO Controls Microbiome Resilience in Hydra

The genetics of human longevity: an intricacy of genes, environment, culture and microbiome

(2017) Serena Dato et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The resilience of the intestinal microbiota influences health and disease

(2017) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

A secreted antibacterial neuropeptide shapes the microbiome of Hydra

(2017) René Augustin et al.   Nature Communications

Regulation of life span by the gut microbiota in the short-lived African turquoise killifish

(2017) Patrick Smith et al.   eLife

Spontaneous body contractions are modulated by the microbiome of Hydra

(2017) Andrea P. Murillo-Rincon et al.   Scientific Reports

Characterization of the direct targets of FOXO transcription factors throughout evolution

(2016) Ashley E. Webb et al.   AGING CELL

The human gut microbiome in health: establishment and resilience of microbiota over a lifetime

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Analysis of factors contributing to variation in the C57BL/6J fecal microbiota across German animal facilities

(2016) Philipp Rausch et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The Origin of Mucosal Immunity: Lessons from the Holobiont Hydra

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A conserved bacterial protein induces pancreatic beta cell expansion during zebrafish development

(2016) Jennifer Hampton Hill et al.   eLife

Transitioning from Microbiome Composition to Microbial Community Interactions: The Potential of the Metaorganism Hydra as an Experimental Model

(2016) Peter Deines et al.   Frontiers in Microbiology

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

(2015) Rute Martins et al.   AGING CELL

Microbiota in Allergy and Asthma and the Emerging Relationship with the Gut Microbiome

(2015) Kei E. Fujimura et al.   Cell Host & Microbe

FOXO3: A Major Gene for Human Longevity - A Mini-Review

(2015) Brian J. Morris et al.   GERONTOLOGY

Intestinal FoxO signaling is required to survive oral infection in Drosophila

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You Are What You Host: Microbiome Modulation of the Aging Process

(2014) Caroline Heintz et al.   CELL

Bacteria–bacteria interactions within the microbiota of the ancestral metazoan Hydra contribute to fungal resistance

(2014) Sebastian Fraune et al.   ISME Journal

Apolipoprotein E isoforms and lipoprotein metabolism

(2014) Michael C. Phillips   IUBMB LIFE

GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy

(2014) Linda Broer et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

FOXO transcription factors: key regulators of cellular quality control

(2014) Ashley E. Webb et al.   TRENDS IN BIOCHEMICAL SCIENCES

Host Demise as a Beneficial Function of Indigenous Microbiota in Human Hosts

(2014) Martin J. Blaser et al.   mBio

FOXO in aging: Did evolutionary diversification of FOXO function distract it from prolonging life?

(2013) Ralf Schaible et al.   BIOESSAYS

Stem cells and aging from a quasi-immortal point of view

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The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Clostridium difficile Infection in the Elderly

(2013) Jonathan M. Keller et al.   CLINICS IN GERIATRIC MEDICINE

Human intestinal metagenomics: state of the art and future

(2013) Hervé M Blottière et al.   CURRENT OPINION IN MICROBIOLOGY

Disruption of the gut microbiome as a risk factor for microbial infections

(2013) Arya Khosravi et al.   CURRENT OPINION IN MICROBIOLOGY

FOXO Transcription Factors Regulate Innate Immune Mechanisms in Respiratory Epithelial Cells

(2013) F. Seiler et al.   JOURNAL OF IMMUNOLOGY

Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

(2013) Marco Candela et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Distinct antimicrobial peptide expression determines host species-specific bacterial associations

(2013) S. Franzenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

Molecular Signatures of the Three Stem Cell Lineages in Hydra and the Emergence of Stem Cell Function at the Base of Multicellularity

(2012) Georg Hemmrich et al.   MOLECULAR BIOLOGY AND EVOLUTION

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

FoxO is a critical regulator of stem cell maintenance in immortal Hydra

(2012) A.-M. Boehm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers

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Ageing of the human metaorganism: the microbial counterpart

(2011) Elena Biagi et al.   AGE

Quality control and preprocessing of metagenomic datasets

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The Complex Biology of FOXO

(2011) Maria Monsalve et al.   CURRENT DRUG TARGETS

Enteric pathogen exploitation of the microbiota-generated nutrient environment of the gut

(2011) Kristie M Keeney et al.   CURRENT OPINION IN MICROBIOLOGY

Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons

(2011) B. J. Haas et al.   GENOME RESEARCH

The skin microbiome

(2011) Elizabeth A. Grice et al.   NATURE REVIEWS MICROBIOLOGY

Metaorganisms as the new frontier

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Metagenomic biomarker discovery and explanation

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Influence of the Composition of the Cellulolytic Flora on the Development of Hydrogenotrophic Microorganisms, Hydrogen Utilization, and Methane Production in the Rumens of Gnotobiotically Reared Lambs

(2010) F. Chaucheyras-Durand et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

FOXO-dependent regulation of innate immune homeostasis

(2010) Thomas Becker et al.   NATURE

Erratum: The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

FoxO and Stress Responses in the Cnidarian Hydra vulgaris

(2010) Diane Bridge et al.   PLoS One

Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88

(2010) S. E. Cheesman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides

(2010) S. Fraune et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis in pre-Bilaterians: Hydra as a model

(2009) Margherita Lasi et al.   APOPTOSIS

Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat

(2009) Andrew L. Goodman et al.   Cell Host & Microbe

Identification of a kazal-type serine protease inhibitor with potent anti-staphylococcal activity as part of Hydra's innate immune system

(2009) René Augustin et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Disturbing epithelial homeostasis in the metazoanHydraleads to drastic changes in associated microbiota

(2009) Sebastian Fraune et al.   ENVIRONMENTAL MICROBIOLOGY

The DAF-2 insulin-like signaling pathway independently regulates aging and immunity inC. elegans

(2008) Eric A. Evans et al.   AGING CELL

A simple and loss-free method to remove TRIzol contaminations from minute RNA samples

(2008) Stefan Krebs et al.   ANALYTICAL BIOCHEMISTRY

Hydramacin-1, Structure and Antibacterial Activity of a Protein from the Basal MetazoanHydra

(2008) Sascha Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXO3A genotype is strongly associated with human longevity

(2008) B. J. Willcox et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA