Lattice defects induce microtubule self-renewal

Tipping microtubule dynamics, one protofilament at a time

(2018) Amol Aher et al.   CURRENT OPINION IN CELL BIOLOGY

Microtubule architecture in vitro and in cells revealed by cryo-electron tomography

(2018) Joseph Atherton et al.   Acta Crystallographica Section D-Structural Biology

Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation

(2018) Annapurna Vemu et al.   SCIENCE

Autoregulation and repair in microtubule homeostasis

(2018) Ivana Gasic et al.   CURRENT OPINION IN CELL BIOLOGY

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

(2017) Elizabeth H. Kellogg et al.   JOURNAL OF MOLECULAR BIOLOGY

Manipulation and quantification of microtubule lattice integrity

(2017) Taylor A. Reid et al.   Biology Open

Localized Mechanical Stress Promotes Microtubule Rescue

(2016) Hélène de Forges et al.   CURRENT BIOLOGY

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

(2016) Harinath Doodhi et al.   CURRENT BIOLOGY

Self-repair promotes microtubule rescue

(2016) Charlotte Aumeier et al.   NATURE CELL BIOLOGY

The size of the EB cap determines instantaneous microtubule stability

(2016) Christian Duellberg et al.   eLife

Microtubules self-repair in response to mechanical stress

(2015) Laura Schaedel et al.   NATURE MATERIALS

Control of microtubule organization and dynamics: two ends in the limelight

(2015) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

Quantification of MAP and molecular motor activities on geometrically controlled microtubule networks

(2012) Didier Portran et al.   Cytoskeleton

Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy

(2012) Hiroaki Yajima et al.   JOURNAL OF CELL BIOLOGY

Rapid Microtubule Self-Assembly Kinetics

(2011) Melissa K. Gardner et al.   CELL

Structural Basis of Interprotofilament Interaction and Lateral Deformation of Microtubules

(2010) Haixin Sui et al.   STRUCTURE

Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly

(2009) Zhanghan Wu et al.   PLoS One

EB1 regulates microtubule dynamics and tubulin sheet closure in vitro

(2008) Benjamin Vitre et al.   NATURE CELL BIOLOGY

Detection of GTP-Tubulin Conformation in Vivo Reveals a Role for GTP Remnants in Microtubule Rescues

(2008) A. Dimitrov et al.   SCIENCE

The physical basis of microtubule structure and stability

(2003) David Sept et al.   PROTEIN SCIENCE