Microtubule architecture in vitro and in cells revealed by cryo-electron tomography

TOG–tubulin binding specificity promotes microtubule dynamics and mitotic spindle formation

(2017) Amy E. Byrnes et al.   JOURNAL OF CELL BIOLOGY

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

(2017) Elizabeth H. Kellogg et al.   JOURNAL OF MOLECULAR BIOLOGY

Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4 Å

(2017) Beata Turoňová et al.   JOURNAL OF STRUCTURAL BIOLOGY

Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging

(2017) Wim J.H. Hagen et al.   JOURNAL OF STRUCTURAL BIOLOGY

Tubulin isoform composition tunes microtubule dynamics

(2017) Annapurna Vemu et al.   MOLECULAR BIOLOGY OF THE CELL

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Convolutional neural networks for automated annotation of cellular cryo-electron tomograms

(2017) Muyuan Chen et al.   NATURE METHODS

The nano-architecture of the axonal cytoskeleton

(2017) Christophe Leterrier et al.   NATURE REVIEWS NEUROSCIENCE

A structural model for microtubule minus-end recognition and protection by CAMSAP proteins

(2017) Joseph Atherton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

(2017) Roderick P. Tas et al.   NEURON

C. elegans chromosomes connect to centrosomes by anchoring into the spindle network

(2017) Stefanie Redemann et al.   Nature Communications

Nucleotide– and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics

(2017) Ottilie von Loeffelholz et al.   Nature Communications

Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins

(2017) Muneyoshi Ichikawa et al.   Nature Communications

A structural model for microtubule minus-end recognition and protection by CAMSAP proteins

(2017) Joseph Atherton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Towards correlative super-resolution fluorescence and electron cryo-microscopy

(2016) Georg Wolff et al.   BIOLOGY OF THE CELL

Microtubule Defects Influence Kinesin-Based Transport In Vitro

(2016) Winnie H. Liang et al.   BIOPHYSICAL JOURNAL

Localized Mechanical Stress Promotes Microtubule Rescue

(2016) Hélène de Forges et al.   CURRENT BIOLOGY

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

(2016) Harinath Doodhi et al.   CURRENT BIOLOGY

Visualizing microtubule structural transitions and interactions with associated proteins

(2016) Eva Nogales et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin

(2016) Annapurna Vemu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of apico–basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7

(2016) Ivar Noordstra et al.   JOURNAL OF CELL SCIENCE

Self-repair promotes microtubule rescue

(2016) Charlotte Aumeier et al.   NATURE CELL BIOLOGY

EB1 interacts with outwardly curved and straight regions of the microtubule lattice

(2016) Audrey Guesdon et al.   NATURE CELL BIOLOGY

Microtubule doublets are double-track railways for intraflagellar transport trains

(2016) L. Stepanek et al.   SCIENCE

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

(2015) Rui Zhang et al.   CELL

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Microtubules self-repair in response to mechanical stress

(2015) Laura Schaedel et al.   NATURE MATERIALS

Control of microtubule organization and dynamics: two ends in the limelight

(2015) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells

(2015) Mika Toya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α- and β-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography

(2015) Aditi Maheshwari et al.   STRUCTURE

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase

(2014) Agnieszka Szyk et al.   CELL

Microtubule Minus-End Stabilization by Polymerization-Driven CAMSAP Deposition

(2014) Kai Jiang et al.   DEVELOPMENTAL CELL

The contribution of αβ-tubulin curvature to microtubule dynamics

(2014) Gary J. Brouhard et al.   JOURNAL OF CELL BIOLOGY

Microtubule Minus-End Binding Protein CAMSAP2 Controls Axon Specification and Dendrite Development

(2014) Kah Wai Yau et al.   NEURON

Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin

(2014) M. C. Hendershott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A molecular ruler determines the repeat length in eukaryotic cilia and flagella

(2014) T. Oda et al.   SCIENCE

The Resolution Revolution

(2014) W. Kuhlbrandt   SCIENCE

Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia

(2014) Jianfeng Lin et al.   Nature Communications

An atomic model of brome mosaic virus using direct electron detection and real-space optimization

(2014) Zhao Wang et al.   Nature Communications

The Microtubule Minus-End-Binding Protein Patronin/PTRN-1 Is Required for Axon Regeneration in C. elegans

(2014) Marian Chuang et al.   Cell Reports

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules

(2012) N. Tanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biophysics of mitosis

(2012) J. Richard McIntosh et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision

(2011) Wanda Kukulski et al.   JOURNAL OF CELL BIOLOGY

The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin

(2011) Agata Nawrotek et al.   JOURNAL OF MOLECULAR BIOLOGY

GTP S microtubules mimic the growing microtubule end structure recognized by end-binding proteins (EBs)

(2011) S. P. Maurer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tubulin depolymerization may be an ancient biological motor

(2010) J. R. McIntosh et al.   JOURNAL OF CELL SCIENCE

Axon Extension Occurs Independently of Centrosomal Microtubule Nucleation

(2010) M. Stiess et al.   SCIENCE

Fibrils Connect Microtubule Tips with Kinetochores: A Mechanism to Couple Tubulin Dynamics to Chromosome Motion

(2008) J. Richard McIntosh et al.   CELL

EB1 regulates microtubule dynamics and tubulin sheet closure in vitro

(2008) Benjamin Vitre et al.   NATURE CELL BIOLOGY

Detection of GTP-Tubulin Conformation in Vivo Reveals a Role for GTP Remnants in Microtubule Rescues

(2008) A. Dimitrov et al.   SCIENCE