Manipulation and quantification of microtubule lattice integrity

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

(2017) Elizabeth H. Kellogg et al.   JOURNAL OF MOLECULAR BIOLOGY

Microtubule Defects Influence Kinesin-Based Transport In Vitro

(2016) Winnie H. Liang et al.   BIOPHYSICAL JOURNAL

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

(2016) Harinath Doodhi et al.   CURRENT BIOLOGY

EB1 interacts with outwardly curved and straight regions of the microtubule lattice

(2016) Audrey Guesdon et al.   NATURE CELL BIOLOGY

Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1

(2016) Courtney Coombes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

(2015) Rui Zhang et al.   CELL

Microtubules self-repair in response to mechanical stress

(2015) Laura Schaedel et al.   NATURE MATERIALS

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

Doublecortin Recognizes the Longitudinal Curvature of the Microtubule End and Lattice

(2014) Susanne Bechstedt et al.   CURRENT BIOLOGY

Mechanical effects of EB1 on microtubules depend on GTP hydrolysis state and presence of paclitaxel

(2014) Benjamin J. Lopez et al.   Cytoskeleton

Mechanical Properties of Doubly Stabilized Microtubule Filaments

(2013) Taviare L. Hawkins et al.   BIOPHYSICAL JOURNAL

Mechanism for the catastrophe-promoting activity of the microtubule destabilizer Op18/stathmin

(2013) K. K. Gupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends

(2012) Sebastian P. Maurer et al.   CELL

Doublecortin Recognizes the 13-Protofilament Microtubule Cooperatively and Tracks Microtubule Ends

(2012) Susanne Bechstedt et al.   DEVELOPMENTAL CELL

Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy

(2012) Hiroaki Yajima et al.   JOURNAL OF CELL BIOLOGY

Force spectroscopy of complex biopolymers with heterogeneous elasticity

(2012) David Valdman et al.   Soft Matter

Modulation of Microtubule Interprotofilament Interactions by Modified Taxanes

(2011) Ruth Matesanz et al.   BIOPHYSICAL JOURNAL

Rapid Microtubule Self-Assembly Kinetics

(2011) Melissa K. Gardner et al.   CELL

Temperature dependence rigidity of non-taxol stabilized single microtubules

(2010) Kenji Kawaguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EB1 regulates microtubule dynamics and tubulin sheet closure in vitro

(2008) Benjamin Vitre et al.   NATURE CELL BIOLOGY

Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice

(2008) Amédée des Georges et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY