SC79, a novel Akt activator, protects dopaminergic neuronal cells from MPP+ and rotenone

Four-octyl itaconate activates Keap1-Nrf2 signaling to protect neuronal cells from hydrogen peroxide

(2018) Hua Liu et al.   Cell Communication and Signaling

Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson’s Disease

(2017) Mesfer Al Shahrani et al.   Journal of Clinical Medicine

SC79 rescues osteoblasts from dexamethasone though activating Akt-Nrf2 signaling

(2016) Song-tao Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of DJ-1/PARK7, the Parkinson's disease-related protein, improves mitochondrial function via Akt phosphorylation on threonine 308 in dopaminergic neuron-like cells

(2016) Yi Zhang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuroprotective Effects of a Standardized Flavonoid Extract from Safflower against a Rotenone-Induced Rat Model of Parkinson’s Disease

(2016) Nuramatjan Ablat et al.   MOLECULES

Gardenamide A Protects RGC-5 Cells from H2O2-Induced Oxidative Stress Insults by Activating PI3K/Akt/eNOS Signaling Pathway

(2015) Rikang Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Salidroside inhibits oxygen glucose deprivation (OGD)/re-oxygenation-induced H9c2 cell necrosis through activating of Akt–Nrf2 signaling

(2014) Koulong Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Squamosamide derivative FLZ protected dopaminergic neuron by activating Akt signaling pathway in 6-OHDA-induced in vivo and in vitro Parkinson's disease models

(2014) Xiu-Qi Bao et al.   BRAIN RESEARCH

Mitochondria: Prospective Targets for Neuroprotection in Parkinson’s Disease

(2014) Anuradha Yadav et al.   CURRENT PHARMACEUTICAL DESIGN

Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling

(2014) Hui Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parkinson’s disease: animal models and dopaminergic cell vulnerability

(2014) Javier Blesa et al.   Frontiers in Neuroanatomy

Histone Decacetylase Inhibitors Prevent Mitochondrial Fragmentation and Elicit Early Neuroprotection against MPP+

(2013) Min Zhu et al.   CNS Neuroscience & Therapeutics

Magnolol Protects Against Oxidative Stress-Mediated Neural Cell Damage by Modulating Mitochondrial Dysfunction and PI3K/Akt Signaling

(2013) Liqun Dong et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP+and rotenone

(2013) Varduhi H. Knaryan et al.   JOURNAL OF NEUROCHEMISTRY

Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

(2013) David J. Irwin et al.   NATURE REVIEWS NEUROSCIENCE

Pseudomonas aeruginosa Pyocyanin Activates NRF2-ARE-Mediated Transcriptional Response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP Kinase Signaling in Pulmonary Epithelial Cells

(2013) Ying Xu et al.   PLoS One

Ginsenoside Rg-1 Protects Retinal Pigment Epithelium (RPE) Cells from Cobalt Chloride (CoCl2) and Hypoxia Assaults

(2013) Ke-ran Li et al.   PLoS One

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

(2012) Tharine Dal-Cim et al.   NEUROCHEMISTRY INTERNATIONAL

Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death

(2012) H. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells

(2011) Yoon-Jin Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Phosphatidylinositol 3-kinase/Akt Signaling Pathway Mediates Acupuncture-Induced Dopaminergic Neuron Protection and Motor Function Improvement in a Mouse Model of Parkinson's Disease

(2011) Seung-Nam Kim et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Transcribe to Survive: Transcriptional Control of Antioxidant Defense Programs for Neuroprotection in Parkinson’s Disease

(2008) Joanne Clark et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons

(2008) Wen Ji Yuan et al.   BMC NEUROSCIENCE