Transcribe to Survive: Transcriptional Control of Antioxidant Defense Programs for Neuroprotection in Parkinson’s Disease

Dynamic regulation of PGC-1α localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response

(2009) Rozalyn M. Anderson et al.   AGING CELL

Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3β signaling pathways and changes in protein expression

(2008) Ana I. Duarte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Potent induction of total cellular GSH and NQO1 as well as mitochondrial GSH by 3H-1,2-dithiole-3-thione in SH-SY5Y neuroblastoma cells and primary human neurons: Protection against neurocytotoxicity elicited by dopamine, 6-hydroxydopamine, 4-hydroxy-2-nonenal, or hydrogen peroxide

(2008) Zhenquan Jia et al.   BRAIN RESEARCH

The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B

(2008) L P Quinn et al.   BRITISH JOURNAL OF PHARMACOLOGY

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

PI3 kinase/Akt activation mediates estrogen and IGF-1 nigral DA neuronal neuroprotection against a unilateral rat model of Parkinson's disease

(2008) Arnulfo Quesada et al.   Developmental Neurobiology

Oxidative stress-inducible lentiviral vectors for gene therapy

(2008) H Hurttila et al.   GENE THERAPY

SCFCdc4 acts antagonistically to the PGC-1  transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis

(2008) B. L. Olson et al.   GENES & DEVELOPMENT

Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

(2008) Patrick L. Apopa et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Phosphorylation and Dephosphorylation of Tyrosine 141 Regulate Stability and Degradation of INrf2

(2008) Abhinav K. Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple Nuclear Localization Signals Function in the Nuclear Import of the Transcription Factor Nrf2

(2008) Melanie Theodore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson’s disease

(2008) Fang Liu et al.   JOURNAL OF NEUROCHEMISTRY

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Dopamine as a Potent Inducer of Cellular Glutathione and NAD(P)H:Quinone Oxidoreductase 1 in PC12 Neuronal Cells: A Potential Adaptive Mechanism for Dopaminergic Neuroprotection

(2008) Zhenquan Jia et al.   NEUROCHEMICAL RESEARCH

Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: Novel cytoprotective mechanism against oxidative damage

(2008) Ju Hee Lim et al.   PHARMACOLOGICAL RESEARCH

Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction

(2008) K. J. Pearson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3  Inactivation

(2008) T. M. Thornton et al.   SCIENCE

Small Maf Proteins in Mammalian Gene Control: Mere Dimerization Partners or Dynamic Transcriptional Regulators?

(2007) Volker Blank   JOURNAL OF MOLECULAR BIOLOGY